FR2407929A1 - Nouveaux derives de 4-amino-2-(piperazin-1-yl ou homopiperazin-1-yl)-quinazoline, leur procede de production et composition pharmaceutique les contenant - Google Patents

Nouveaux derives de 4-amino-2-(piperazin-1-yl ou homopiperazin-1-yl)-quinazoline, leur procede de production et composition pharmaceutique les contenant

Info

Publication number
FR2407929A1
FR2407929A1 FR7831126A FR7831126A FR2407929A1 FR 2407929 A1 FR2407929 A1 FR 2407929A1 FR 7831126 A FR7831126 A FR 7831126A FR 7831126 A FR7831126 A FR 7831126A FR 2407929 A1 FR2407929 A1 FR 2407929A1
Authority
FR
France
Prior art keywords
homopiperazin
quinazoline
piperazin
amino
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7831126A
Other languages
English (en)
French (fr)
Other versions
FR2407929B1 (enrdf_load_stackoverflow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Publication of FR2407929A1 publication Critical patent/FR2407929A1/fr
Application granted granted Critical
Publication of FR2407929B1 publication Critical patent/FR2407929B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR7831126A 1977-11-05 1978-11-03 Nouveaux derives de 4-amino-2-(piperazin-1-yl ou homopiperazin-1-yl)-quinazoline, leur procede de production et composition pharmaceutique les contenant Granted FR2407929A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05

Publications (2)

Publication Number Publication Date
FR2407929A1 true FR2407929A1 (fr) 1979-06-01
FR2407929B1 FR2407929B1 (enrdf_load_stackoverflow) 1981-02-27

Family

ID=10439957

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7831126A Granted FR2407929A1 (fr) 1977-11-05 1978-11-03 Nouveaux derives de 4-amino-2-(piperazin-1-yl ou homopiperazin-1-yl)-quinazoline, leur procede de production et composition pharmaceutique les contenant

Country Status (36)

Country Link
JP (1) JPS5498792A (enrdf_load_stackoverflow)
AR (2) AR219562A1 (enrdf_load_stackoverflow)
AT (1) AT365186B (enrdf_load_stackoverflow)
AU (1) AU509329B2 (enrdf_load_stackoverflow)
BE (1) BE871771A (enrdf_load_stackoverflow)
CA (1) CA1088059A (enrdf_load_stackoverflow)
CH (1) CH643255A5 (enrdf_load_stackoverflow)
CS (2) CS207671B2 (enrdf_load_stackoverflow)
DD (1) DD139850A5 (enrdf_load_stackoverflow)
DE (1) DE2847623C2 (enrdf_load_stackoverflow)
DK (1) DK154082C (enrdf_load_stackoverflow)
EG (1) EG13594A (enrdf_load_stackoverflow)
ES (2) ES474805A1 (enrdf_load_stackoverflow)
FI (1) FI64366C (enrdf_load_stackoverflow)
FR (1) FR2407929A1 (enrdf_load_stackoverflow)
GR (1) GR81514B (enrdf_load_stackoverflow)
HK (1) HK94284A (enrdf_load_stackoverflow)
HU (1) HU176306B (enrdf_load_stackoverflow)
IE (1) IE47888B1 (enrdf_load_stackoverflow)
IL (1) IL55857A (enrdf_load_stackoverflow)
IN (1) IN148828B (enrdf_load_stackoverflow)
IT (1) IT1100919B (enrdf_load_stackoverflow)
KE (1) KE3350A (enrdf_load_stackoverflow)
LU (2) LU80470A1 (enrdf_load_stackoverflow)
MY (1) MY8500286A (enrdf_load_stackoverflow)
NL (2) NL174549C (enrdf_load_stackoverflow)
NO (1) NO150158C (enrdf_load_stackoverflow)
NZ (1) NZ188813A (enrdf_load_stackoverflow)
PH (1) PH13966A (enrdf_load_stackoverflow)
PL (2) PL119419B1 (enrdf_load_stackoverflow)
PT (1) PT68735A (enrdf_load_stackoverflow)
SE (1) SE437518B (enrdf_load_stackoverflow)
SU (1) SU816403A3 (enrdf_load_stackoverflow)
UA (1) UA8324A1 (enrdf_load_stackoverflow)
YU (2) YU40204B (enrdf_load_stackoverflow)
ZA (1) ZA786184B (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1403263A1 (en) * 2002-09-27 2004-03-31 Council of Scientific and Industrial Research Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985002617A1 (en) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1985004658A1 (en) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepine derivatives and their preparation
WO1986002644A1 (en) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
DE59611417D1 (de) * 1996-12-20 2007-03-29 Heumann Pharma Gmbh & Co Neue polymorphe Form von Doxazosinmesylat (Form III)
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
EP0849264A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1403263A1 (en) * 2002-09-27 2004-03-31 Council of Scientific and Industrial Research Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Also Published As

Publication number Publication date
DK154082C (da) 1989-02-27
KE3350A (en) 1983-12-16
YU40204B (en) 1985-08-31
PL119419B1 (en) 1981-12-31
NL174549B (nl) 1984-02-01
ES474805A1 (es) 1980-01-16
NZ188813A (en) 1980-10-08
IE782179L (en) 1979-05-05
MY8500286A (en) 1985-12-31
LU80470A1 (fr) 1980-06-05
AR219562A1 (es) 1980-08-29
FR2407929B1 (enrdf_load_stackoverflow) 1981-02-27
YU40419B (en) 1985-12-31
AT365186B (de) 1981-12-28
IL55857A0 (en) 1979-01-31
DD139850A5 (de) 1980-01-23
SE7811382L (sv) 1979-05-06
AR223015A1 (es) 1981-07-15
CH643255A5 (en) 1984-05-30
IT1100919B (it) 1985-09-28
UA8324A1 (uk) 1996-03-29
NL174549C (nl) 1984-07-02
AU509329B2 (en) 1980-05-08
PL119586B1 (en) 1982-01-30
ES8308559A1 (es) 1980-07-16
JPS5498792A (en) 1979-08-03
AU4132278A (en) 1979-05-17
ATA784378A (de) 1981-05-15
DE2847623A1 (de) 1979-05-23
IL55857A (en) 1982-07-30
PT68735A (en) 1978-12-01
JPS5625233B2 (enrdf_load_stackoverflow) 1981-06-11
SU816403A3 (ru) 1981-03-23
YU38683A (en) 1983-06-30
NO150158B (no) 1984-05-21
PH13966A (en) 1980-11-12
SE437518B (sv) 1985-03-04
IT7829434A0 (it) 1978-11-03
PL210681A1 (enrdf_load_stackoverflow) 1979-11-05
NL930062I2 (nl) 1993-11-16
DK154082B (da) 1988-10-10
CS207671B2 (en) 1981-08-31
IE47888B1 (en) 1984-07-11
DK428678A (da) 1979-05-06
ES480121A0 (es) 1980-07-16
NL7810909A (nl) 1979-05-08
FI64366B (fi) 1983-07-29
NO150158C (no) 1984-08-29
HU176306B (en) 1981-01-28
CA1088059A (en) 1980-10-21
NL930062I1 (nl) 1993-09-01
GR81514B (enrdf_load_stackoverflow) 1984-12-11
YU255378A (en) 1983-06-30
DE2847623C2 (de) 1983-06-01
LU88331I2 (fr) 1994-05-04
HK94284A (en) 1984-12-07
EG13594A (en) 1982-03-31
NO783705L (no) 1979-05-08
FI783347A7 (fi) 1979-05-06
ZA786184B (en) 1979-10-31
IN148828B (enrdf_load_stackoverflow) 1981-06-27
BE871771A (fr) 1979-05-03
CS354491A3 (en) 1992-06-17
FI64366C (fi) 1983-11-10

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0342, 920527

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0342, 781103

CL Concession to grant licences