FR2374336A1 - Nouveaux derives acyles de l'hellebrigenine - Google Patents
Nouveaux derives acyles de l'hellebrigenineInfo
- Publication number
- FR2374336A1 FR2374336A1 FR7737795A FR7737795A FR2374336A1 FR 2374336 A1 FR2374336 A1 FR 2374336A1 FR 7737795 A FR7737795 A FR 7737795A FR 7737795 A FR7737795 A FR 7737795A FR 2374336 A1 FR2374336 A1 FR 2374336A1
- Authority
- FR
- France
- Prior art keywords
- hellebrigenin
- acyl derivatives
- new acyl
- new
- forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- TVKPTWJPKVSGJB-XHCIOXAKSA-N (3s,5s,8r,9s,10s,13r,14s,17r)-3,5,14-trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene-10-carbaldehyde Chemical class C=1([C@H]2CC[C@]3(O)[C@H]4[C@@H]([C@]5(CC[C@H](O)C[C@@]5(O)CC4)C=O)CC[C@@]32C)C=CC(=O)OC=1 TVKPTWJPKVSGJB-XHCIOXAKSA-N 0.000 title 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB52759/76A GB1577633A (en) | 1976-12-17 | 1976-12-17 | Acyl derivatives of hellebrigenin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2374336A1 true FR2374336A1 (fr) | 1978-07-13 |
| FR2374336B1 FR2374336B1 (show.php) | 1980-11-07 |
Family
ID=10465185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7737795A Granted FR2374336A1 (fr) | 1976-12-17 | 1977-12-15 | Nouveaux derives acyles de l'hellebrigenine |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS591279B2 (show.php) |
| AT (1) | AT372391B (show.php) |
| BE (1) | BE861968A (show.php) |
| CH (1) | CH639107A5 (show.php) |
| DD (1) | DD133151A5 (show.php) |
| DE (1) | DE2755122C2 (show.php) |
| ES (2) | ES465135A1 (show.php) |
| FI (1) | FI58135C (show.php) |
| FR (1) | FR2374336A1 (show.php) |
| GB (1) | GB1577633A (show.php) |
| HU (1) | HU176767B (show.php) |
| IT (1) | IT1113251B (show.php) |
| PL (1) | PL110178B1 (show.php) |
| SU (2) | SU751328A3 (show.php) |
| ZA (1) | ZA777494B (show.php) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61158784U (show.php) * | 1985-03-25 | 1986-10-01 | ||
| EP1108702A1 (en) * | 1999-12-13 | 2001-06-20 | Kvaerner Process Technology Limited | Process for the co-production of aliphatic diols and cyclic ethers |
| WO2010102673A1 (en) * | 2009-03-13 | 2010-09-16 | Unibioscreen S.A. | Hellebrin and hellebrigenin derivatives |
| WO2011134954A1 (en) * | 2010-04-27 | 2011-11-03 | Pharma Mar, S.A. | Anticancer steroidal lactones unsaturated in position 7 (8) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1901484A1 (de) * | 1969-01-14 | 1970-10-29 | Hoechst Ag | Herzwirksame Oxyester von Steroid-Cardenoliden und -Bufandienoliden und Verfahren zu ihrer Herstellung |
-
1976
- 1976-12-17 GB GB52759/76A patent/GB1577633A/en not_active Expired
-
1977
- 1977-12-10 DE DE2755122A patent/DE2755122C2/de not_active Expired
- 1977-12-13 IT IT52184/77A patent/IT1113251B/it active
- 1977-12-15 SU SU772553849A patent/SU751328A3/ru active
- 1977-12-15 ZA ZA00777494A patent/ZA777494B/xx unknown
- 1977-12-15 FR FR7737795A patent/FR2374336A1/fr active Granted
- 1977-12-16 PL PL1977203030A patent/PL110178B1/pl not_active IP Right Cessation
- 1977-12-16 DD DD7700202719A patent/DD133151A5/xx unknown
- 1977-12-16 HU HU77DE947A patent/HU176767B/hu unknown
- 1977-12-16 JP JP52152295A patent/JPS591279B2/ja not_active Expired
- 1977-12-16 FI FI773814A patent/FI58135C/fi not_active IP Right Cessation
- 1977-12-16 AT AT0903877A patent/AT372391B/de not_active IP Right Cessation
- 1977-12-16 BE BE6046270A patent/BE861968A/xx not_active IP Right Cessation
- 1977-12-16 ES ES465135A patent/ES465135A1/es not_active Expired
- 1977-12-16 ES ES465136A patent/ES465136A1/es not_active Expired
-
1978
- 1978-01-01 CH CH1554377A patent/CH639107A5/de not_active IP Right Cessation
- 1978-12-25 SU SU782701599A patent/SU795487A3/ru active
Non-Patent Citations (1)
| Title |
|---|
| CA1968 * |
Also Published As
| Publication number | Publication date |
|---|---|
| DD133151A5 (de) | 1978-12-13 |
| SU751328A3 (ru) | 1980-07-23 |
| FI58135C (fi) | 1980-12-10 |
| ES465135A1 (es) | 1978-10-01 |
| CH639107A5 (de) | 1983-10-31 |
| ATA903877A (de) | 1983-02-15 |
| DE2755122C2 (de) | 1983-06-30 |
| JPS591279B2 (ja) | 1984-01-11 |
| AT372391B (de) | 1983-09-26 |
| PL203030A1 (pl) | 1979-03-26 |
| ES465136A1 (es) | 1979-01-01 |
| IT1113251B (it) | 1986-01-20 |
| HU176767B (en) | 1981-05-28 |
| PL110178B1 (en) | 1980-07-31 |
| FI58135B (fi) | 1980-08-29 |
| GB1577633A (en) | 1980-10-29 |
| BE861968A (fr) | 1978-06-16 |
| FI773814A7 (fi) | 1978-06-18 |
| FR2374336B1 (show.php) | 1980-11-07 |
| DE2755122A1 (de) | 1978-06-22 |
| SU795487A3 (ru) | 1981-01-07 |
| ZA777494B (en) | 1979-02-28 |
| JPS5395956A (en) | 1978-08-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |