FR2374336A1 - NEW ACYL DERIVATIVES OF HELLEBRIGENIN - Google Patents

NEW ACYL DERIVATIVES OF HELLEBRIGENIN

Info

Publication number
FR2374336A1
FR2374336A1 FR7737795A FR7737795A FR2374336A1 FR 2374336 A1 FR2374336 A1 FR 2374336A1 FR 7737795 A FR7737795 A FR 7737795A FR 7737795 A FR7737795 A FR 7737795A FR 2374336 A1 FR2374336 A1 FR 2374336A1
Authority
FR
France
Prior art keywords
hellebrigenin
acyl derivatives
new acyl
new
forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7737795A
Other languages
French (fr)
Other versions
FR2374336B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH, Deutsche Gold und Silber Scheideanstalt filed Critical Degussa GmbH
Publication of FR2374336A1 publication Critical patent/FR2374336A1/en
Application granted granted Critical
Publication of FR2374336B1 publication Critical patent/FR2374336B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Ce sont les composés de la formule I ci-après ainsi que leurs formes optiquement actives et leurs sels. Indications : tous les degrés et formes d'insuffisance cardiaque et de coeur sénile.These are the compounds of formula I below as well as their optically active forms and their salts. Indications: all degrees and forms of heart failure and senile heart.

FR7737795A 1976-12-17 1977-12-15 NEW ACYL DERIVATIVES OF HELLEBRIGENIN Granted FR2374336A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB52759/76A GB1577633A (en) 1976-12-17 1976-12-17 Acyl derivatives of hellebrigenin

Publications (2)

Publication Number Publication Date
FR2374336A1 true FR2374336A1 (en) 1978-07-13
FR2374336B1 FR2374336B1 (en) 1980-11-07

Family

ID=10465185

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7737795A Granted FR2374336A1 (en) 1976-12-17 1977-12-15 NEW ACYL DERIVATIVES OF HELLEBRIGENIN

Country Status (15)

Country Link
JP (1) JPS591279B2 (en)
AT (1) AT372391B (en)
BE (1) BE861968A (en)
CH (1) CH639107A5 (en)
DD (1) DD133151A5 (en)
DE (1) DE2755122C2 (en)
ES (2) ES465136A1 (en)
FI (1) FI58135C (en)
FR (1) FR2374336A1 (en)
GB (1) GB1577633A (en)
HU (1) HU176767B (en)
IT (1) IT1113251B (en)
PL (1) PL110178B1 (en)
SU (2) SU751328A3 (en)
ZA (1) ZA777494B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61158784U (en) * 1985-03-25 1986-10-01
EP1108702A1 (en) * 1999-12-13 2001-06-20 Kvaerner Process Technology Limited Process for the co-production of aliphatic diols and cyclic ethers
WO2010102673A1 (en) * 2009-03-13 2010-09-16 Unibioscreen S.A. Hellebrin and hellebrigenin derivatives
PL2563803T3 (en) * 2010-04-27 2016-08-31 Pharma Mar Sa Anticancer steroidal lactones unsaturated in position 7(8)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1901484A1 (en) * 1969-01-14 1970-10-29 Hoechst Ag Cardiac active oxyesters of steroid cardenolides and steroid bufandienolides and processes for their preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1968 *

Also Published As

Publication number Publication date
PL110178B1 (en) 1980-07-31
FI58135B (en) 1980-08-29
SU751328A3 (en) 1980-07-23
BE861968A (en) 1978-06-16
PL203030A1 (en) 1979-03-26
DD133151A5 (en) 1978-12-13
CH639107A5 (en) 1983-10-31
ES465135A1 (en) 1978-10-01
GB1577633A (en) 1980-10-29
AT372391B (en) 1983-09-26
JPS5395956A (en) 1978-08-22
DE2755122C2 (en) 1983-06-30
HU176767B (en) 1981-05-28
DE2755122A1 (en) 1978-06-22
JPS591279B2 (en) 1984-01-11
FR2374336B1 (en) 1980-11-07
FI58135C (en) 1980-12-10
FI773814A (en) 1978-06-18
SU795487A3 (en) 1981-01-07
ES465136A1 (en) 1979-01-01
IT1113251B (en) 1986-01-20
ZA777494B (en) 1979-02-28
ATA903877A (en) 1983-02-15

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Legal Events

Date Code Title Description
ST Notification of lapse