PL110178B1 - Method of producing new acyl derivatives of hellebrigenine - Google Patents

Method of producing new acyl derivatives of hellebrigenine Download PDF

Info

Publication number
PL110178B1
PL110178B1 PL1977203030A PL20303077A PL110178B1 PL 110178 B1 PL110178 B1 PL 110178B1 PL 1977203030 A PL1977203030 A PL 1977203030A PL 20303077 A PL20303077 A PL 20303077A PL 110178 B1 PL110178 B1 PL 110178B1
Authority
PL
Poland
Prior art keywords
group
carbon atoms
acid
solution
preparation
Prior art date
Application number
PL1977203030A
Other languages
English (en)
Polish (pl)
Other versions
PL203030A1 (pl
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of PL203030A1 publication Critical patent/PL203030A1/xx
Publication of PL110178B1 publication Critical patent/PL110178B1/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J19/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL1977203030A 1976-12-17 1977-12-16 Method of producing new acyl derivatives of hellebrigenine PL110178B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB52759/76A GB1577633A (en) 1976-12-17 1976-12-17 Acyl derivatives of hellebrigenin

Publications (2)

Publication Number Publication Date
PL203030A1 PL203030A1 (pl) 1979-03-26
PL110178B1 true PL110178B1 (en) 1980-07-31

Family

ID=10465185

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1977203030A PL110178B1 (en) 1976-12-17 1977-12-16 Method of producing new acyl derivatives of hellebrigenine

Country Status (15)

Country Link
JP (1) JPS591279B2 (show.php)
AT (1) AT372391B (show.php)
BE (1) BE861968A (show.php)
CH (1) CH639107A5 (show.php)
DD (1) DD133151A5 (show.php)
DE (1) DE2755122C2 (show.php)
ES (2) ES465135A1 (show.php)
FI (1) FI58135C (show.php)
FR (1) FR2374336A1 (show.php)
GB (1) GB1577633A (show.php)
HU (1) HU176767B (show.php)
IT (1) IT1113251B (show.php)
PL (1) PL110178B1 (show.php)
SU (2) SU751328A3 (show.php)
ZA (1) ZA777494B (show.php)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61158784U (show.php) * 1985-03-25 1986-10-01
EP1108702A1 (en) * 1999-12-13 2001-06-20 Kvaerner Process Technology Limited Process for the co-production of aliphatic diols and cyclic ethers
WO2010102673A1 (en) * 2009-03-13 2010-09-16 Unibioscreen S.A. Hellebrin and hellebrigenin derivatives
WO2011134954A1 (en) * 2010-04-27 2011-11-03 Pharma Mar, S.A. Anticancer steroidal lactones unsaturated in position 7 (8)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1901484A1 (de) * 1969-01-14 1970-10-29 Hoechst Ag Herzwirksame Oxyester von Steroid-Cardenoliden und -Bufandienoliden und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
DD133151A5 (de) 1978-12-13
SU751328A3 (ru) 1980-07-23
FI58135C (fi) 1980-12-10
ES465135A1 (es) 1978-10-01
CH639107A5 (de) 1983-10-31
ATA903877A (de) 1983-02-15
DE2755122C2 (de) 1983-06-30
JPS591279B2 (ja) 1984-01-11
AT372391B (de) 1983-09-26
PL203030A1 (pl) 1979-03-26
ES465136A1 (es) 1979-01-01
IT1113251B (it) 1986-01-20
HU176767B (en) 1981-05-28
FI58135B (fi) 1980-08-29
GB1577633A (en) 1980-10-29
BE861968A (fr) 1978-06-16
FI773814A7 (fi) 1978-06-18
FR2374336B1 (show.php) 1980-11-07
DE2755122A1 (de) 1978-06-22
SU795487A3 (ru) 1981-01-07
ZA777494B (en) 1979-02-28
FR2374336A1 (fr) 1978-07-13
JPS5395956A (en) 1978-08-22

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20050130