FI960280A0 - Uusi fuusioitunut indaanijohdannainen ja sen farmaseuttisesti hyväksyttävä suola - Google Patents
Uusi fuusioitunut indaanijohdannainen ja sen farmaseuttisesti hyväksyttävä suolaInfo
- Publication number
- FI960280A0 FI960280A0 FI960280A FI960280A FI960280A0 FI 960280 A0 FI960280 A0 FI 960280A0 FI 960280 A FI960280 A FI 960280A FI 960280 A FI960280 A FI 960280A FI 960280 A0 FI960280 A0 FI 960280A0
- Authority
- FI
- Finland
- Prior art keywords
- group
- substituted
- optionally substituted
- ring
- nitrogenous heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10719094 | 1994-05-20 | ||
JP10719094 | 1994-05-20 | ||
PCT/JP1995/000944 WO1995032187A1 (fr) | 1994-05-20 | 1995-05-18 | Nouveau derive d'indane fusionne et sel dudit derive acceptable pharmaceutiquement |
JP9500944 | 1995-05-18 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI960280A0 true FI960280A0 (fi) | 1996-01-19 |
FI960280A FI960280A (fi) | 1996-03-18 |
FI111721B FI111721B (fi) | 2003-09-15 |
Family
ID=14452758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI960280A FI111721B (fi) | 1994-05-20 | 1996-01-19 | Uusi kondensoitu indaanijohdannainen ja sen farmaseuttisesti hyväksyttävä suola |
Country Status (21)
Country | Link |
---|---|
US (3) | US5733918A (fi) |
EP (1) | EP0713870B1 (fi) |
KR (1) | KR100190732B1 (fi) |
CN (1) | CN1131216C (fi) |
AT (1) | ATE203236T1 (fi) |
AU (1) | AU685631B2 (fi) |
CA (1) | CA2167382C (fi) |
DE (1) | DE69521770T2 (fi) |
DK (1) | DK0713870T3 (fi) |
ES (1) | ES2158109T3 (fi) |
FI (1) | FI111721B (fi) |
GR (1) | GR3036795T3 (fi) |
HU (1) | HU218308B (fi) |
IL (1) | IL113778A (fi) |
NO (1) | NO305555B1 (fi) |
NZ (1) | NZ285448A (fi) |
PT (1) | PT713870E (fi) |
RU (1) | RU2124017C1 (fi) |
TW (1) | TW440562B (fi) |
WO (1) | WO1995032187A1 (fi) |
ZA (1) | ZA954077B (fi) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3141148B2 (ja) * | 1995-08-08 | 2001-03-05 | 大鵬薬品工業株式会社 | 縮合インダン誘導体及びその塩 |
US20030096833A1 (en) * | 2001-08-31 | 2003-05-22 | Jagtap Prakash G. | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof |
US6956035B2 (en) * | 2001-08-31 | 2005-10-18 | Inotek Pharmaceuticals Corporation | Isoquinoline derivatives and methods of use thereof |
CN1284781C (zh) * | 2001-10-05 | 2006-11-15 | 霍夫曼-拉罗奇有限公司 | 具有抗肿瘤活性的多环化合物 |
US6946472B2 (en) | 2002-04-30 | 2005-09-20 | Hoffman-La Roche Inc. | Polycyclic compounds exhibiting anti-tumor activities |
CL2004000366A1 (es) * | 2003-02-26 | 2005-01-07 | Pharmacia Corp Sa Organizada B | USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA. |
JP2007501857A (ja) * | 2003-02-28 | 2007-02-01 | イノテック ファーマシューティカルズ コーポレーション | 四環系ベンズアミド誘導体およびその使用方法 |
EP1722797A4 (en) * | 2004-02-26 | 2008-03-19 | Inotek Pharmaceuticals Corp | ISOCHINOLINE DERIVATIVES AND METHOD FOR THE APPLICATION THEREOF |
JP2007525526A (ja) * | 2004-02-26 | 2007-09-06 | イノテック ファーマシューティカルズ コーポレイション | 四環系ラクタム誘導体およびその使用 |
AU2005264980A1 (en) * | 2004-06-16 | 2006-01-26 | Inotek Pharmaceuticals Corporation | Methods for treating or preventing erectile dysfunction or urinary incontinence |
WO2006091769A1 (en) * | 2005-02-24 | 2006-08-31 | Janssen Pharmaceutica N.V. | Novel quinoline derivatives as potassium ion channel openers |
RU2007135362A (ru) * | 2005-02-25 | 2009-03-27 | Инотек Фармасьютикалз Корпорейшн (Us) | Тетрациклические амино- и карбоксамидосоединения и способ их применения |
EP1850848A4 (en) * | 2005-02-25 | 2008-02-20 | Inotek Pharmaceuticals Corp | SULFONAMIDE TETRACYCLIC COMPOUNDS AND METHODS OF USING THE SAME |
MX2007010335A (es) * | 2005-02-25 | 2007-11-06 | Inotek Pharmaceuticals Corp | Compuestos de isoquinolina y metodos de uso de los mismos. |
BRPI0615096A2 (pt) * | 2005-08-24 | 2009-07-14 | Inotek Pharmaceuticals Corp | análogos de indenoisoquinolinona e métodos de uso dos mesmos |
US8119654B2 (en) * | 2007-02-28 | 2012-02-21 | Inotek Pharmaceuticals Corporation | Indenoisoquinolinone analogs and methods of use thereof |
CN103102304B (zh) * | 2013-01-19 | 2015-03-11 | 安徽师范大学 | N-磺酰基取代四氢异喹啉衍生物的制备方法 |
MY182891A (en) | 2013-08-22 | 2021-02-05 | Taiho Pharmaceutical Co Ltd | Novel quinoline-substituted compound |
JOP20190073A1 (ar) | 2016-10-31 | 2019-04-07 | Taiho Pharmaceutical Co Ltd | مثبط انتقائي لمستقبل عامل نمو بشروي (egfr) لطافر إدخال exon 20 |
FI3677266T3 (fi) | 2017-09-01 | 2024-03-22 | Taiho Pharmaceutical Co Ltd | Eksoni 18- ja/tai eksoni 21 -egfr-mutantille selektiivinen inhibiittori |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5223506A (en) * | 1991-06-04 | 1993-06-29 | Glaxo Inc. | Cyclic antitumor compounds |
-
1995
- 1995-05-17 TW TW084104882A patent/TW440562B/zh not_active IP Right Cessation
- 1995-05-18 ZA ZA954077A patent/ZA954077B/xx unknown
- 1995-05-18 CN CN95190639A patent/CN1131216C/zh not_active Expired - Fee Related
- 1995-05-18 ES ES95918733T patent/ES2158109T3/es not_active Expired - Lifetime
- 1995-05-18 NZ NZ285448A patent/NZ285448A/en unknown
- 1995-05-18 CA CA002167382A patent/CA2167382C/en not_active Expired - Fee Related
- 1995-05-18 HU HU9600130A patent/HU218308B/hu not_active IP Right Cessation
- 1995-05-18 DK DK95918733T patent/DK0713870T3/da active
- 1995-05-18 WO PCT/JP1995/000944 patent/WO1995032187A1/ja active IP Right Grant
- 1995-05-18 AT AT95918733T patent/ATE203236T1/de not_active IP Right Cessation
- 1995-05-18 EP EP95918733A patent/EP0713870B1/en not_active Expired - Lifetime
- 1995-05-18 KR KR1019960700277A patent/KR100190732B1/ko not_active IP Right Cessation
- 1995-05-18 IL IL11377895A patent/IL113778A/xx not_active IP Right Cessation
- 1995-05-18 US US08/578,542 patent/US5733918A/en not_active Expired - Fee Related
- 1995-05-18 RU RU96105034A patent/RU2124017C1/ru not_active IP Right Cessation
- 1995-05-18 AU AU24542/95A patent/AU685631B2/en not_active Ceased
- 1995-05-18 DE DE69521770T patent/DE69521770T2/de not_active Expired - Fee Related
- 1995-05-18 PT PT95918733T patent/PT713870E/pt unknown
-
1996
- 1996-01-19 NO NO960239A patent/NO305555B1/no unknown
- 1996-01-19 FI FI960280A patent/FI111721B/fi active
- 1996-09-12 US US08/713,224 patent/US5710162A/en not_active Expired - Fee Related
-
1997
- 1997-08-12 US US08/909,934 patent/US6028079A/en not_active Expired - Fee Related
-
2001
- 2001-10-04 GR GR20010401657T patent/GR3036795T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2167382A1 (en) | 1995-11-30 |
IL113778A (en) | 1999-09-22 |
NO960239L (no) | 1996-03-18 |
FI960280A (fi) | 1996-03-18 |
FI111721B (fi) | 2003-09-15 |
US5710162A (en) | 1998-01-20 |
KR960703864A (ko) | 1996-08-31 |
RU2124017C1 (ru) | 1998-12-27 |
CA2167382C (en) | 1999-08-31 |
ATE203236T1 (de) | 2001-08-15 |
WO1995032187A1 (fr) | 1995-11-30 |
NO960239D0 (no) | 1996-01-19 |
DK0713870T3 (da) | 2001-09-24 |
NZ285448A (en) | 1997-11-24 |
CN1131216C (zh) | 2003-12-17 |
EP0713870B1 (en) | 2001-07-18 |
EP0713870A4 (en) | 1996-12-18 |
DE69521770D1 (de) | 2001-08-23 |
AU685631B2 (en) | 1998-01-22 |
IL113778A0 (en) | 1995-08-31 |
KR100190732B1 (ko) | 1999-06-01 |
NO305555B1 (no) | 1999-06-21 |
EP0713870A1 (en) | 1996-05-29 |
TW440562B (en) | 2001-06-16 |
ZA954077B (en) | 1996-01-19 |
DE69521770T2 (de) | 2002-05-23 |
ES2158109T3 (es) | 2001-09-01 |
GR3036795T3 (en) | 2002-01-31 |
PT713870E (pt) | 2001-11-30 |
HUT75651A (en) | 1997-05-28 |
HU218308B (en) | 2000-07-28 |
CN1130903A (zh) | 1996-09-11 |
AU2454295A (en) | 1995-12-18 |
US5733918A (en) | 1998-03-31 |
US6028079A (en) | 2000-02-22 |
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