FI960280A0 - Nytt kondenserat indanderivat och farmaceutiskt acceptabelt salt därav - Google Patents

Nytt kondenserat indanderivat och farmaceutiskt acceptabelt salt därav

Info

Publication number
FI960280A0
FI960280A0 FI960280A FI960280A FI960280A0 FI 960280 A0 FI960280 A0 FI 960280A0 FI 960280 A FI960280 A FI 960280A FI 960280 A FI960280 A FI 960280A FI 960280 A0 FI960280 A0 FI 960280A0
Authority
FI
Finland
Prior art keywords
group
substituted
optionally substituted
ring
nitrogenous heterocyclic
Prior art date
Application number
FI960280A
Other languages
English (en)
Finnish (fi)
Other versions
FI960280A (sv
FI111721B (sv
Inventor
Shinji Okazaki
Tetsuji Asao
Motoji Wakida
Keisuke Ishida
Masato Washinosu
Teruhiro Utsugi
Yuji Yamada
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of FI960280A0 publication Critical patent/FI960280A0/sv
Publication of FI960280A publication Critical patent/FI960280A/sv
Application granted granted Critical
Publication of FI111721B publication Critical patent/FI111721B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI960280A 1994-05-20 1996-01-19 Nytt kondenserat indanderivat och farmaceutiskt acceptabelt salt därav FI111721B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10719094 1994-05-20
JP10719094 1994-05-20
JP9500944 1995-05-18
PCT/JP1995/000944 WO1995032187A1 (fr) 1994-05-20 1995-05-18 Nouveau derive d'indane fusionne et sel dudit derive acceptable pharmaceutiquement

Publications (3)

Publication Number Publication Date
FI960280A0 true FI960280A0 (sv) 1996-01-19
FI960280A FI960280A (sv) 1996-03-18
FI111721B FI111721B (sv) 2003-09-15

Family

ID=14452758

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960280A FI111721B (sv) 1994-05-20 1996-01-19 Nytt kondenserat indanderivat och farmaceutiskt acceptabelt salt därav

Country Status (21)

Country Link
US (3) US5733918A (sv)
EP (1) EP0713870B1 (sv)
KR (1) KR100190732B1 (sv)
CN (1) CN1131216C (sv)
AT (1) ATE203236T1 (sv)
AU (1) AU685631B2 (sv)
CA (1) CA2167382C (sv)
DE (1) DE69521770T2 (sv)
DK (1) DK0713870T3 (sv)
ES (1) ES2158109T3 (sv)
FI (1) FI111721B (sv)
GR (1) GR3036795T3 (sv)
HU (1) HU218308B (sv)
IL (1) IL113778A (sv)
NO (1) NO305555B1 (sv)
NZ (1) NZ285448A (sv)
PT (1) PT713870E (sv)
RU (1) RU2124017C1 (sv)
TW (1) TW440562B (sv)
WO (1) WO1995032187A1 (sv)
ZA (1) ZA954077B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
US6956035B2 (en) * 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) * 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
EP1436293B1 (en) * 2001-10-05 2006-02-01 F. Hoffmann-La Roche Ag Polycyclic compounds having anti-tumor activity
US6946472B2 (en) * 2002-04-30 2005-09-20 Hoffman-La Roche Inc. Polycyclic compounds exhibiting anti-tumor activities
CL2004000366A1 (es) * 2003-02-26 2005-01-07 Pharmacia Corp Sa Organizada B USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.
EP1603567A4 (en) * 2003-02-28 2006-10-18 Inotek Pharmaceuticals Corp TETRACYCLIC BENZAMIDE DERIVATIVES AND METHOD OF USE THEREOF
EP1722796A4 (en) * 2004-02-26 2008-01-23 Inotek Pharmaceuticals Corp TETRACYCLIC LACTAM DERIVATIVES AND USES THEREOF
CA2557547A1 (en) * 2004-02-26 2005-09-09 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
CA2571001A1 (en) * 2004-06-16 2006-01-26 Inotek Pharmaceuticals Corporation Methods for treating or preventing erectile dysfunction or urinary incontinence
CA2599151A1 (en) * 2005-02-24 2006-08-31 Janssen Pharmaceutica N.V. Novel quinoline derivatives as potassium ion channel openers
JP2008531562A (ja) * 2005-02-25 2008-08-14 イノテック ファーマシューティカルズ コーポレイション 四環アミノ化合物および四環カルボキサミド化合物およびこれらの使用法
MX2007010335A (es) * 2005-02-25 2007-11-06 Inotek Pharmaceuticals Corp Compuestos de isoquinolina y metodos de uso de los mismos.
EP1850848A4 (en) * 2005-02-25 2008-02-20 Inotek Pharmaceuticals Corp SULFONAMIDE TETRACYCLIC COMPOUNDS AND METHODS OF USING THE SAME
EP1937268A4 (en) * 2005-08-24 2009-07-22 Inotek Pharmaceuticals Corp INDENOISOQUINOLINONE ANALOGUES AND METHODS OF USE
JP2010520220A (ja) * 2007-02-28 2010-06-10 イノテック ファーマシューティカルズ コーポレイション インデノイソキノリノン類似体およびその使用方法
CN103102304B (zh) * 2013-01-19 2015-03-11 安徽师范大学 N-磺酰基取代四氢异喹啉衍生物的制备方法
WO2015025936A1 (ja) 2013-08-22 2015-02-26 大鵬薬品工業株式会社 新規キノリン置換化合物
JOP20190073A1 (ar) 2016-10-31 2019-04-07 Taiho Pharmaceutical Co Ltd مثبط انتقائي لمستقبل عامل نمو بشروي (egfr) لطافر إدخال exon 20
JP7065103B2 (ja) 2017-09-01 2022-05-11 大鵬薬品工業株式会社 エクソン１８及び／又はエクソン２１変異型ｅｇｆｒ選択的阻害剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223506A (en) * 1991-06-04 1993-06-29 Glaxo Inc. Cyclic antitumor compounds

Also Published As

Publication number Publication date
DK0713870T3 (da) 2001-09-24
KR960703864A (ko) 1996-08-31
CA2167382A1 (en) 1995-11-30
GR3036795T3 (en) 2002-01-31
WO1995032187A1 (fr) 1995-11-30
HUT75651A (en) 1997-05-28
DE69521770T2 (de) 2002-05-23
HU218308B (en) 2000-07-28
CN1131216C (zh) 2003-12-17
DE69521770D1 (de) 2001-08-23
IL113778A0 (en) 1995-08-31
CN1130903A (zh) 1996-09-11
NO305555B1 (no) 1999-06-21
EP0713870B1 (en) 2001-07-18
ZA954077B (en) 1996-01-19
US6028079A (en) 2000-02-22
US5710162A (en) 1998-01-20
EP0713870A1 (en) 1996-05-29
AU2454295A (en) 1995-12-18
NZ285448A (en) 1997-11-24
FI960280A (sv) 1996-03-18
KR100190732B1 (ko) 1999-06-01
NO960239L (no) 1996-03-18
RU2124017C1 (ru) 1998-12-27
TW440562B (en) 2001-06-16
IL113778A (en) 1999-09-22
ATE203236T1 (de) 2001-08-15
EP0713870A4 (en) 1996-12-18
FI111721B (sv) 2003-09-15
ES2158109T3 (es) 2001-09-01
AU685631B2 (en) 1998-01-22
PT713870E (pt) 2001-11-30
US5733918A (en) 1998-03-31
CA2167382C (en) 1999-08-31
NO960239D0 (no) 1996-01-19

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