FI960173A0 - Menetelmä sakkaridikoostumusten syntetisoimiseksi - Google Patents

Menetelmä sakkaridikoostumusten syntetisoimiseksi

Info

Publication number
FI960173A0
FI960173A0 FI960173A FI960173A FI960173A0 FI 960173 A0 FI960173 A0 FI 960173A0 FI 960173 A FI960173 A FI 960173A FI 960173 A FI960173 A FI 960173A FI 960173 A0 FI960173 A0 FI 960173A0
Authority
FI
Finland
Prior art keywords
saccharide compositions
synthesizing
synthesizing saccharide
compositions
saccharide
Prior art date
Application number
FI960173A
Other languages
English (en)
Swedish (sv)
Other versions
FI960173A (fi
Inventor
Stephen Roth
Original Assignee
Neose Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neose Pharm Inc filed Critical Neose Pharm Inc
Publication of FI960173A0 publication Critical patent/FI960173A0/fi
Publication of FI960173A publication Critical patent/FI960173A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI960173A 1993-07-15 1996-01-15 Menetelmä sakkaridikoostumusten syntetisoimiseksi FI960173A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9137293A 1993-07-15 1993-07-15
PCT/US1994/007807 WO1995002683A1 (en) 1993-07-15 1994-07-15 Method of synthesizing saccharide compositions

Publications (2)

Publication Number Publication Date
FI960173A0 true FI960173A0 (fi) 1996-01-15
FI960173A FI960173A (fi) 1996-03-15

Family

ID=22227422

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960173A FI960173A (fi) 1993-07-15 1996-01-15 Menetelmä sakkaridikoostumusten syntetisoimiseksi

Country Status (9)

Country Link
US (2) US5879912A (fi)
EP (1) EP0785988A1 (fi)
JP (1) JPH09503905A (fi)
CN (1) CN1129953A (fi)
AU (1) AU691510B2 (fi)
CA (1) CA2167157A1 (fi)
FI (1) FI960173A (fi)
NO (1) NO960177L (fi)
WO (1) WO1995002683A1 (fi)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2237586A1 (en) * 1996-09-13 1998-03-19 Kyowa Hakko Kogyo Co., Ltd. Processes for producing sugar nucleotides and complex carbohydrates
AU4220397A (en) * 1996-09-17 1998-04-14 Kyowa Hakko Kogyo Co. Ltd. Processes for producing sugar nucleotides and complex carbohydrates
HUP0001634A2 (hu) 1996-10-10 2000-09-28 Cytel Corporation Szénhidrátok tisztítása ultraszűréssel, fordított ozmózissal és nanoszűréssel
US6045854A (en) * 1997-03-31 2000-04-04 Abbott Laboraties Nutritional formulations containing oligosaccharides
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
DE19716731A1 (de) * 1997-04-14 1998-10-15 Biopract Gmbh Verfahren zur enzymatischen Herstellung von Fructosylverbindungen
US7060469B2 (en) * 1998-04-02 2006-06-13 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
DE69940353D1 (en) * 1998-11-11 2009-03-12 Univ Oklahoma Polymerpfropfung mittels polysaccharide-synthase
US20060105431A1 (en) * 1998-11-11 2006-05-18 Deangelis Paul L Polymer grafting by polysaccharide synthases using artificial sugar acceptors
ES2558160T3 (es) 1998-12-09 2016-02-02 Phyton Holdings, Llc Glicoproteínas que tienen glicosilación de tipo humano
US6699705B2 (en) * 1999-02-01 2004-03-02 National Research Council Of Canada Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
AU5407300A (en) * 1999-06-30 2001-01-22 Novartis Ag Ophthalmic molding
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
DE60044858D1 (de) 1999-10-26 2010-09-30 Stichting Dienst Landbouwkundi Säugetierartige Glykosylierung in Pflanzen
US7534589B2 (en) * 1999-11-10 2009-05-19 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
US20020132320A1 (en) * 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
BRPI0206546B1 (pt) 2001-01-19 2015-07-21 Phyton Holdings Llc Método para a produção secretória de glicoproteína que tem cadeia de açúcar do tipo humana, usando célula vegetal
WO2002070672A2 (en) * 2001-03-06 2002-09-12 The Dow Chemical Company Plant cell having animal-type sugar chain adding function
WO2003017949A2 (en) 2001-08-29 2003-03-06 Neose Technologies, Inc. Novel synthetic ganglioside derivatives and compositions thereof
WO2003025133A2 (en) * 2001-09-14 2003-03-27 Mimeon, Inc. Methods of making glycolmolecules with enhanced activities and uses thereof
US20040214228A9 (en) * 2001-09-14 2004-10-28 Ganesh Venkataraman Methods of evaluating glycomolecules for enhanced activities
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
DK1578771T3 (da) * 2001-10-10 2013-06-10 Novo Nordisk As Remodellering og glycokonjugering af peptider
KR100527437B1 (ko) * 2001-11-20 2005-11-09 한국생명공학연구원 β-1,4-갈락토실트랜스퍼라제의 생산방법
US20030166866A1 (en) * 2002-01-28 2003-09-04 Land O' Lakes, Inc. Method of processing a proteinaceous material to recover K-casein macropeptide and polymers of a-lactalbumin and B-lactoglobulin
JP4048289B2 (ja) * 2002-02-26 2008-02-20 独立行政法人科学技術振興機構 微細自己集合体
JP4052553B2 (ja) * 2002-03-07 2008-02-27 独立行政法人科学技術振興機構 微細自己集合体の製法
CN101613705A (zh) 2002-03-19 2009-12-30 国际植物研究所 在植物中优化聚糖生成
EP2319934B1 (en) 2002-03-19 2015-09-02 Stichting Dienst Landbouwkundig Onderzoek GnTIII (UDP-N-acetylglucosamine:Beta -D mannoside Beta (1,4)-N-acetylglucosaminyltransferase III) expression in plants.
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
US20040147033A1 (en) * 2002-12-20 2004-07-29 Zachary Shriver Glycan markers for diagnosing and monitoring disease
JP4405736B2 (ja) 2003-01-31 2010-01-27 コニカミノルタホールディングス株式会社 データベースシステム
JP2004261885A (ja) * 2003-02-18 2004-09-24 Japan Science & Technology Agency 有機ナノチューブへ機能性物質を導入する方法
NZ567841A (en) 2003-03-06 2010-01-29 Seneb Biosciences Inc Methods and compositions for the enzymatic synthesis of gangliosides
CA2522345A1 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
WO2006010143A2 (en) 2004-07-13 2006-01-26 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
EP3061461A1 (en) 2004-10-29 2016-08-31 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
NZ556436A (en) 2005-01-10 2010-11-26 Biogenerix Ag Glycopegylated granulocyte colony stimulating factor
EP2386571B1 (en) 2005-04-08 2016-06-01 ratiopharm GmbH Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
JP2006143723A (ja) * 2005-11-16 2006-06-08 Japan Science & Technology Agency 微細自己集合体
US20080248959A1 (en) 2006-07-21 2008-10-09 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
JP2010505874A (ja) 2006-10-03 2010-02-25 ノヴォ ノルディスク アー／エス ポリペプチドコンジュゲートの精製方法
NZ580030A (en) 2007-04-03 2012-06-29 Biogenerix Ag Methods of treatment using glycopegylated g-csf
EP2137655B1 (en) * 2007-04-16 2012-07-11 Momenta Pharmaceuticals, Inc. Defined glycoprotein products and related methods
CA2684370C (en) 2007-04-17 2017-10-17 Plant Research International B.V. Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
EP2170919B8 (en) 2007-06-12 2016-01-20 ratiopharm GmbH Improved process for the production of nucleotide sugars
US20120035120A1 (en) 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
SG10201709458QA (en) 2010-06-02 2017-12-28 Evolva Inc Recombinant production of steviol glycosides
WO2012125553A2 (en) 2011-03-12 2012-09-20 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing n-glycans in glycoprotein products
EP2722394B1 (en) 2011-06-07 2018-03-21 Hero AG Obtaining oligosaccharides by means of a biotechnological process
SG10201606565XA (en) 2011-08-08 2016-10-28 Evolva Sa Recombinant production of steviol glycosides
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
US9957540B2 (en) 2013-02-06 2018-05-01 Evolva Sa Methods for improved production of Rebaudioside D and Rebaudioside M
SG10201705993YA (en) 2013-02-11 2017-08-30 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
WO2014149067A1 (en) 2013-03-15 2014-09-25 Momenta Pharmaceuticals, Inc. Methods related to ctla4-fc fusion proteins
US10464996B2 (en) 2013-05-13 2019-11-05 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
EP3058084A4 (en) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
CA2957331A1 (en) 2014-08-11 2016-02-18 Evolva Sa Production of steviol glycosides in recombinant hosts
CA2960693A1 (en) 2014-09-09 2016-03-17 Evolva Sa Production of steviol glycosides in recombinant hosts
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
SG11201705606PA (en) 2015-01-30 2017-08-30 Evolva Sa Production of steviol glycosides in recombinant hosts
CA2979931A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
CA2995067A1 (en) 2015-08-07 2017-02-16 Evolva Sa Production of steviol glycosides in recombinant hosts
CN109195457A (zh) 2016-04-13 2019-01-11 埃沃尔瓦公司 在重组宿主中产生甜菊醇糖苷
US11312741B2 (en) 2016-04-19 2022-04-26 Glycom A/S Separation of oligosaccharides from fermentation broth
EP3458599A1 (en) 2016-05-16 2019-03-27 Evolva SA Production of steviol glycosides in recombinant hosts
CN110100006A (zh) 2016-11-07 2019-08-06 埃沃尔瓦公司 重组宿主中甜菊糖苷的生产
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58149697A (ja) * 1982-02-27 1983-09-06 Dainippon Ink & Chem Inc β−１，３グリコシルステビオシドの製造方法
US5135854A (en) * 1987-10-29 1992-08-04 Zymogenetics, Inc. Methods of regulating protein glycosylation
FR2626583B1 (fr) * 1988-01-29 1991-03-15 Bioeurope Procede de preparation enzymatique d'oligodextranes utiles dans la fabrication de substituts du sucre, et nouveaux oligodextranes
US5047335A (en) * 1988-12-21 1991-09-10 The Regents Of The University Of Calif. Process for controlling intracellular glycosylation of proteins
US5149640A (en) * 1988-12-22 1992-09-22 Ajinomoto Co., Inc. Method for producing galactose transfer products
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
US5324663A (en) * 1990-02-14 1994-06-28 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
EP0481038B1 (en) * 1990-04-16 2002-10-02 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
US5348867A (en) * 1991-11-15 1994-09-20 George Georgiou Expression of proteins on bacterial surface
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them

Also Published As

Publication number Publication date
AU7329994A (en) 1995-02-13
NO960177D0 (no) 1996-01-15
AU691510B2 (en) 1998-05-21
EP0785988A4 (fi) 1997-07-30
CN1129953A (zh) 1996-08-28
NO960177L (no) 1996-03-07
JPH09503905A (ja) 1997-04-22
EP0785988A1 (en) 1997-07-30
US6284493B1 (en) 2001-09-04
WO1995002683A1 (en) 1995-01-26
US5879912A (en) 1999-03-09
CA2167157A1 (en) 1995-01-26
FI960173A (fi) 1996-03-15

Similar Documents

Publication Publication Date Title
FI960173A0 (fi) Menetelmä sakkaridikoostumusten syntetisoimiseksi
FI974241A0 (fi) BPM-15 -koostumukset
IT1276979B1 (it) Composizioni fluoroelastomeriche
DE69614819T2 (de) Herstellungsverfahren von gefrorenen zusammensetzungen
DE69618854D1 (de) Fotopolymerisierbare Zusammensetzung
BR9610346A (pt) Composições de confeito
DK0533752T3 (da) Forbedret syntesefremgangsmåde
NO953043D0 (no) Fremgangsmåte for syntetisere acetotriglyceridfett
NO981568D0 (no) Randtennings-tennsatssammensetninger
DE69400062D1 (de) Photopolymerisierbare Zusammensetzung
DE69609242T2 (de) Fotopolymerisierbare Zusammensetzungen
KR970001365A (ko) 알킬하이드로겐클로로실란의 제조방법
NO953961L (no) Antihypertriglyseridemisk sammensetning
DE69604601T2 (de) Fotopolymerisierbare Zusammensetzung
DE69503738D1 (de) Fotopolymerisierbare Zusammensetzung
BR9609903A (pt) ComposiçÃo inseticidamente ativa
DE69616374D1 (de) Germizide zusammensetzung
FI971035A (fi) Biokonversioprosessi trans-hydroksisulfonin syntetisoimiseksi
ID18917A (id) Proses untuk sintesis benzotiofena
DE69603228T2 (de) Aluminoxanate-Zusammensetzungen
ATE206150T1 (de) Farbstoffstabilisierte zusammensetzungen
MA23731A1 (fr) Compositions detegentes
DE69605584T2 (de) Fotopolymerisierbare Zusammensetzung
BA98312A (bs) Cvrsta kompozicija
NO970747D0 (no) Sammensetninger