FI960173A - Menetelmä sakkaridikoostumusten syntetisoimiseksi - Google Patents

Menetelmä sakkaridikoostumusten syntetisoimiseksi Download PDF

Info

Publication number
FI960173A
FI960173A FI960173A FI960173A FI960173A FI 960173 A FI960173 A FI 960173A FI 960173 A FI960173 A FI 960173A FI 960173 A FI960173 A FI 960173A FI 960173 A FI960173 A FI 960173A
Authority
FI
Finland
Prior art keywords
saccharide compositions
synthesizing
synthesizing saccharide
compositions
saccharide
Prior art date
Application number
FI960173A
Other languages
English (en)
Swedish (sv)
Other versions
FI960173A0 (fi
Inventor
Stephen Roth
Original Assignee
Neose Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neose Pharm Inc filed Critical Neose Pharm Inc
Publication of FI960173A0 publication Critical patent/FI960173A0/fi
Publication of FI960173A publication Critical patent/FI960173A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI960173A 1993-07-15 1996-01-15 Menetelmä sakkaridikoostumusten syntetisoimiseksi FI960173A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9137293A 1993-07-15 1993-07-15
PCT/US1994/007807 WO1995002683A1 (en) 1993-07-15 1994-07-15 Method of synthesizing saccharide compositions

Publications (2)

Publication Number Publication Date
FI960173A0 FI960173A0 (fi) 1996-01-15
FI960173A true FI960173A (fi) 1996-03-15

Family

ID=22227422

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960173A FI960173A (fi) 1993-07-15 1996-01-15 Menetelmä sakkaridikoostumusten syntetisoimiseksi

Country Status (9)

Country Link
US (2) US5879912A (fi)
EP (1) EP0785988A1 (fi)
JP (1) JPH09503905A (fi)
CN (1) CN1129953A (fi)
AU (1) AU691510B2 (fi)
CA (1) CA2167157A1 (fi)
FI (1) FI960173A (fi)
NO (1) NO960177L (fi)
WO (1) WO1995002683A1 (fi)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4220297A (en) * 1996-09-13 1998-04-02 Kyowa Hakko Kogyo Co. Ltd. Processes for producing sugar nucleotides and complex carbohydrates
US6821756B2 (en) * 1996-09-17 2004-11-23 Kyowa Hakko Kogyo Co., Ltd. Processes for reproducing sugar nucleotides and complex carbohydrates
IL129363A (en) 1996-10-10 2003-02-12 Neose Technologies Inc Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
US6045854A (en) * 1997-03-31 2000-04-04 Abbott Laboraties Nutritional formulations containing oligosaccharides
DE19716731A1 (de) * 1997-04-14 1998-10-15 Biopract Gmbh Verfahren zur enzymatischen Herstellung von Fructosylverbindungen
US7060469B2 (en) * 1998-04-02 2006-06-13 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
WO2000027437A2 (en) * 1998-11-11 2000-05-18 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
US20060105431A1 (en) * 1998-11-11 2006-05-18 Deangelis Paul L Polymer grafting by polysaccharide synthases using artificial sugar acceptors
IL143641A0 (en) * 1998-12-09 2002-04-21 A method for manufacturing glycoproteins having human-type glycosylation
US6699705B2 (en) * 1999-02-01 2004-03-02 National Research Council Of Canada Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
AU5407300A (en) * 1999-06-30 2001-01-22 Novartis Ag Ophthalmic molding
FR2796082B1 (fr) * 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
CA2925231A1 (en) 1999-10-26 2001-05-03 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in transgenic plants expressing galactosyltransferase and sialyl transferase
US7534589B2 (en) * 1999-11-10 2009-05-19 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
US20020132320A1 (en) * 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
CA2434364C (en) 2001-01-19 2013-03-19 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
IL157736A0 (en) * 2001-03-06 2004-03-28 Dow Chemical Co Plant cell having animal-type sugar chain adding function
US7842677B2 (en) 2001-08-29 2010-11-30 Seneb Biosciences, Inc. Synthetic ganglioside derivatives and compositions thereof
EP1438387A4 (en) * 2001-09-14 2004-10-13 Momenta Pharmaceuticals Inc METHODS OF MAKING GLYCOMOLECULES WITH IMPROVED ACTIVITY, AND USES THEREOF
US20040214228A9 (en) * 2001-09-14 2004-10-28 Ganesh Venkataraman Methods of evaluating glycomolecules for enhanced activities
EP2292271A3 (en) * 2001-10-10 2011-09-14 BioGeneriX AG Remodelling and glycoconjugation of an antibody
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
KR100527437B1 (ko) * 2001-11-20 2005-11-09 한국생명공학연구원 β-1,4-갈락토실트랜스퍼라제의 생산방법
US20030166866A1 (en) * 2002-01-28 2003-09-04 Land O' Lakes, Inc. Method of processing a proteinaceous material to recover K-casein macropeptide and polymers of a-lactalbumin and B-lactoglobulin
JP4048289B2 (ja) * 2002-02-26 2008-02-20 独立行政法人科学技術振興機構 微細自己集合体
JP4052553B2 (ja) * 2002-03-07 2008-02-27 独立行政法人科学技術振興機構 微細自己集合体の製法
EP1485492B1 (en) 2002-03-19 2011-12-21 Stichting Dienst Landbouwkundig Onderzoek Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants
JP4532118B2 (ja) 2002-03-19 2010-08-25 スティヒティング ディーンスト ランドバウクンディフ オンデルズーク 植物体内のグリカンプロセシングの最適化
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
EP1587408A4 (en) * 2002-12-20 2007-09-05 Momenta Pharmaceuticals Inc GLYCAN MARKER FOR DIAGNOSIS AND MONITORING OF DISEASES
JP4405736B2 (ja) 2003-01-31 2010-01-27 コニカミノルタホールディングス株式会社 データベースシステム
JP2004261885A (ja) * 2003-02-18 2004-09-24 Japan Science & Technology Agency 有機ナノチューブへ機能性物質を導入する方法
MXPA05009480A (es) 2003-03-06 2006-02-22 Neose Technologies Inc Metodos y composiciones para la sintesis enzimatica de gangliosidos.
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
EP1814573B1 (en) 2004-10-29 2016-03-09 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
CA2593682C (en) 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
JP2006143723A (ja) * 2005-11-16 2006-06-08 Japan Science & Technology Agency 微細自己集合体
JP2009544327A (ja) 2006-07-21 2009-12-17 ノヴォ ノルディスク アー／エス Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
EP2054521A4 (en) 2006-10-03 2012-12-19 Novo Nordisk As METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
KR20150064246A (ko) 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
US20100113294A1 (en) * 2007-04-16 2010-05-06 Momenta Pharmaceuticals, Inc. Defined glycoprotein products and related methods
MX341988B (es) 2007-04-17 2016-09-08 Stichting Dienst Landbouwkunding Onderzoek Glicosilacion tipo mamifera en plantas para la expresion de glicosil-transferasas no mamiferas.
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
WO2010111530A1 (en) 2009-03-25 2010-09-30 Seneb Biosciences, Inc. Glycolipids as treatment for disease
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
MX349121B (es) 2010-06-02 2017-07-12 Evolva Inc Produccion recombinante de esteviol glucosidos.
US9170249B2 (en) 2011-03-12 2015-10-27 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing N-glycans in glycoprotein products
ES2671555T3 (es) 2011-06-07 2018-06-07 Hero Ag Obtención de oligosacáridos mediante un proceso biotecnológico
WO2013022989A2 (en) 2011-08-08 2013-02-14 Evolva Sa Recombinant production of steviol glycosides
US9695244B2 (en) 2012-06-01 2017-07-04 Momenta Pharmaceuticals, Inc. Methods related to denosumab
MX369525B (es) 2013-02-06 2019-11-11 Evolva Sa Métodos para mejorar la produccion de rebaudiosido d y rebaudiosido m.
WO2014122328A1 (en) 2013-02-11 2014-08-14 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
EP2855533A4 (en) 2013-03-15 2015-11-25 Momenta Pharmaceuticals Inc METHODS RELATING TO CTLA4-FC FUSION PROTEINS
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
SG11201700651RA (en) 2014-08-11 2017-02-27 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3190905A2 (en) 2014-09-09 2017-07-19 Evolva SA Production of steviol glycosides in recombinant hosts
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
SG11201705606PA (en) 2015-01-30 2017-08-30 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3862426A3 (en) 2015-03-16 2021-11-17 DSM IP Assets B.V. Udp-glycosyltransferases
CN108271391A (zh) 2015-08-07 2018-07-10 埃沃尔瓦公司 重组宿主中的甜菊醇糖苷的产生
JP2019513392A (ja) 2016-04-13 2019-05-30 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組み換え宿主におけるステビオールグリコシドの産生
US11312741B2 (en) 2016-04-19 2022-04-26 Glycom A/S Separation of oligosaccharides from fermentation broth
CN109312378A (zh) 2016-05-16 2019-02-05 埃沃尔瓦公司 在重组宿主中产生甜菊醇糖苷
WO2018083338A1 (en) 2016-11-07 2018-05-11 Evolva Sa Production of steviol glycosides in recombinant hosts
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58149697A (ja) * 1982-02-27 1983-09-06 Dainippon Ink & Chem Inc β−１，３グリコシルステビオシドの製造方法
US5135854A (en) * 1987-10-29 1992-08-04 Zymogenetics, Inc. Methods of regulating protein glycosylation
FR2626583B1 (fr) * 1988-01-29 1991-03-15 Bioeurope Procede de preparation enzymatique d'oligodextranes utiles dans la fabrication de substituts du sucre, et nouveaux oligodextranes
US5047335A (en) * 1988-12-21 1991-09-10 The Regents Of The University Of Calif. Process for controlling intracellular glycosylation of proteins
US5149640A (en) * 1988-12-22 1992-09-22 Ajinomoto Co., Inc. Method for producing galactose transfer products
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
US5324663A (en) * 1990-02-14 1994-06-28 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
WO1991016449A1 (en) * 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
US5348867A (en) * 1991-11-15 1994-09-20 George Georgiou Expression of proteins on bacterial surface
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them

Also Published As

Publication number Publication date
FI960173A0 (fi) 1996-01-15
NO960177D0 (no) 1996-01-15
CA2167157A1 (en) 1995-01-26
AU691510B2 (en) 1998-05-21
WO1995002683A1 (en) 1995-01-26
NO960177L (no) 1996-03-07
CN1129953A (zh) 1996-08-28
AU7329994A (en) 1995-02-13
US6284493B1 (en) 2001-09-04
EP0785988A4 (fi) 1997-07-30
EP0785988A1 (en) 1997-07-30
US5879912A (en) 1999-03-09
JPH09503905A (ja) 1997-04-22

Similar Documents

Publication Publication Date Title
FI960173A0 (fi) Menetelmä sakkaridikoostumusten syntetisoimiseksi
FI974241A0 (fi) BPM-15 -koostumukset
DE69614819T2 (de) Herstellungsverfahren von gefrorenen zusammensetzungen
DE69618854D1 (de) Fotopolymerisierbare Zusammensetzung
BR9610346A (pt) Composições de confeito
FI102967B1 (fi) Parannettu synteesimenetelmä
NO953043D0 (no) Fremgangsmåte for syntetisere acetotriglyceridfett
NO981568D0 (no) Randtennings-tennsatssammensetninger
BR9607058A (pt) Composição
DE69400062D1 (de) Photopolymerisierbare Zusammensetzung
DE69609242D1 (de) Fotopolymerisierbare Zusammensetzungen
BR9606809A (pt) Composição inseticidamente ativa
KR970001365A (ko) 알킬하이드로겐클로로실란의 제조방법
NO953961D0 (no) Antihypertriglyseridemisk sammensetning
DE69617029D1 (de) Organoton-zusammensetzungen
DE69604601D1 (de) Fotopolymerisierbare Zusammensetzung
NO974169D0 (no) Fremgangsmåte for tetra-azacykloalkan-fremstilling
PT728814E (pt) Composicao betuminosa
DE69616374D1 (de) Germizide zusammensetzung
FI971035A (fi) Biokonversioprosessi trans-hydroksisulfonin syntetisoimiseksi
ID18917A (id) Proses untuk sintesis benzotiofena
DE69603228D1 (de) Aluminoxanate-Zusammensetzungen
EE9800168A (et) Tahked kompositsioonid
DE69605584T2 (de) Fotopolymerisierbare Zusammensetzung
NO970747D0 (no) Sammensetninger