FI956143A - Positiva inotropiska och lusitropiska pyrrolokinolinonderivat - Google Patents

Positiva inotropiska och lusitropiska pyrrolokinolinonderivat Download PDF

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Publication number
FI956143A
FI956143A FI956143A FI956143A FI956143A FI 956143 A FI956143 A FI 956143A FI 956143 A FI956143 A FI 956143A FI 956143 A FI956143 A FI 956143A FI 956143 A FI956143 A FI 956143A
Authority
FI
Finland
Prior art keywords
pct
lusitropic
positive inotropic
pyrroloquinolinone
derivatives
Prior art date
Application number
FI956143A
Other languages
English (en)
Finnish (fi)
Other versions
FI956143A0 (sv
FI109124B (sv
Inventor
Eddy Jean Edgard Freyne
Alfons Herman Marg Raeymaekers
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI956143A0 publication Critical patent/FI956143A0/sv
Publication of FI956143A publication Critical patent/FI956143A/sv
Application granted granted Critical
Publication of FI109124B publication Critical patent/FI109124B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI956143A 1993-06-21 1995-12-20 Förfarande för framställning av positiv inotrop och lusitrop effekt åstadkommande 1,3-dihydro-2H-pyrrolo [2,3-b] kinolin-2-on derivat och mellanprodukt vid förfarande FI109124B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP93201771 1993-06-21
EP93201771 1993-06-21
PCT/EP1994/001960 WO1995000512A1 (en) 1993-06-21 1994-06-15 Positive inotropic and lusitropic pyrroloquinolinone derivatives
EP9401960 1994-06-15

Publications (3)

Publication Number Publication Date
FI956143A0 FI956143A0 (sv) 1995-12-20
FI956143A true FI956143A (sv) 1995-12-20
FI109124B FI109124B (sv) 2002-05-31

Family

ID=8213908

Family Applications (1)

Application Number Title Priority Date Filing Date
FI956143A FI109124B (sv) 1993-06-21 1995-12-20 Förfarande för framställning av positiv inotrop och lusitrop effekt åstadkommande 1,3-dihydro-2H-pyrrolo [2,3-b] kinolin-2-on derivat och mellanprodukt vid förfarande

Country Status (29)

Country Link
US (1) US5602134A (sv)
EP (1) EP0707586B1 (sv)
JP (1) JP2812804B2 (sv)
KR (1) KR0181560B1 (sv)
CN (1) CN1043765C (sv)
AT (1) ATE171179T1 (sv)
AU (1) AU679077B2 (sv)
BG (1) BG62171B1 (sv)
BR (1) BR9406899A (sv)
CA (1) CA2163122C (sv)
CZ (1) CZ284350B6 (sv)
DE (1) DE69413398T2 (sv)
FI (1) FI109124B (sv)
HU (1) HU220670B1 (sv)
IL (1) IL110055A (sv)
LT (1) LT3447B (sv)
LV (1) LV11545B (sv)
MY (1) MY110751A (sv)
NO (1) NO305366B1 (sv)
OA (1) OA10202A (sv)
PH (1) PH31308A (sv)
PL (1) PL176783B1 (sv)
RU (1) RU2129554C1 (sv)
SG (1) SG49717A1 (sv)
SI (1) SI9420041A (sv)
SK (1) SK280400B6 (sv)
TW (1) TW593317B (sv)
WO (1) WO1995000512A1 (sv)
ZA (1) ZA944382B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208497B2 (en) 2001-07-02 2007-04-24 Novo Nordisk A/S Substituted piperazines and diazepanes
EP1434765B1 (en) * 2001-09-14 2009-12-02 High Point Pharmaceuticals, LLC Substituted piperidines with selective binding to histamine h3-receptor
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
GB0808953D0 (en) * 2008-05-16 2008-06-25 Shire Llc substituted quinazolines
GB0808944D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
RU2457208C2 (ru) * 2009-07-06 2012-07-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "ПГФА Росздрава") 1H-ПИРРОЛО[3,4-b]ХИНОЛИН-3,9(2H,4H)-ДИОНЫ, ОБЛАДАЮЩИЕ ПРОТИВОТУБЕРКУЛЕЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ
WO2024149378A1 (zh) * 2023-01-13 2024-07-18 上海超阳药业有限公司 喹啉酮化合物和萘啶酮化合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
CN1030196C (zh) * 1989-07-07 1995-11-01 詹森药业有限公司 增强收缩力和舒张力的-二氢咪唑并喹唑啉酮衍生物的制备方法
NZ234186A (en) * 1989-07-07 1991-10-25 Janssen Pharmaceutica Nv Imidazo quinazolin-one derivatives and pharmaceutical compositions
US5220023A (en) * 1989-07-18 1993-06-15 Janssen Pharmaceutica N.V. Glycine derivatives
US4943573A (en) 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas

Also Published As

Publication number Publication date
AU7000894A (en) 1995-01-17
EP0707586B1 (en) 1998-09-16
NO955028D0 (no) 1995-12-12
WO1995000512A1 (en) 1995-01-05
HUT72090A (en) 1996-03-28
CA2163122C (en) 2005-06-14
FI956143A0 (sv) 1995-12-20
NO305366B1 (no) 1999-05-18
MY110751A (en) 1999-02-27
PH31308A (en) 1998-07-06
LV11545B (en) 1997-08-20
ZA944382B (en) 1995-12-20
HU220670B1 (hu) 2002-04-29
IL110055A0 (en) 1994-10-07
HU9501970D0 (en) 1995-09-28
PL176783B1 (pl) 1999-07-30
IL110055A (en) 1997-09-30
TW593317B (en) 2004-06-21
KR0181560B1 (ko) 1999-05-01
LT3447B (en) 1995-10-25
SK159695A3 (en) 1997-01-08
AU679077B2 (en) 1997-06-19
CN1043765C (zh) 1999-06-23
BG100209A (bg) 1996-07-31
LTIP1960A (en) 1995-01-31
NO955028L (no) 1995-12-12
DE69413398T2 (de) 1999-04-15
US5602134A (en) 1997-02-11
EP0707586A1 (en) 1996-04-24
CN1125945A (zh) 1996-07-03
DE69413398D1 (de) 1998-10-22
JPH09500108A (ja) 1997-01-07
RU2129554C1 (ru) 1999-04-27
JP2812804B2 (ja) 1998-10-22
CA2163122A1 (en) 1995-01-05
ATE171179T1 (de) 1998-10-15
CZ284350B6 (cs) 1998-10-14
FI109124B (sv) 2002-05-31
PL312252A1 (en) 1996-04-01
SG49717A1 (en) 1998-06-15
SI9420041A (en) 1996-08-31
CZ336695A3 (en) 1996-03-13
SK280400B6 (sk) 2000-01-18
BR9406899A (pt) 1996-04-09
OA10202A (en) 1996-12-18
LV11545A (lv) 1996-10-20
BG62171B1 (bg) 1999-04-30

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