FI95573B - Förfarande för framställning av terapeutiskt användbara pyrrolidinderivat - Google Patents
Förfarande för framställning av terapeutiskt användbara pyrrolidinderivatInfo
- Publication number
- FI95573B FI95573B FI901333A FI901333A FI95573B FI 95573 B FI95573 B FI 95573B FI 901333 A FI901333 A FI 901333A FI 901333 A FI901333 A FI 901333A FI 95573 B FI95573 B FI 95573B
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- therapeutically useful
- pyrrolidine derivatives
- chem
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8906166 | 1989-03-17 | ||
GB898906166A GB8906166D0 (en) | 1989-03-17 | 1989-03-17 | Therapeutic agents |
Publications (3)
Publication Number | Publication Date |
---|---|
FI901333A0 FI901333A0 (sv) | 1990-03-16 |
FI95573B true FI95573B (sv) | 1995-11-15 |
FI95573C FI95573C (sv) | 1996-02-26 |
Family
ID=10653525
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI901333A FI95573C (sv) | 1989-03-17 | 1990-03-16 | Förfarande för framställning av terapeutiskt användbara pyrrolidinderivat |
Country Status (37)
Country | Link |
---|---|
US (1) | US5096890B1 (sv) |
EP (1) | EP0388054B1 (sv) |
JP (2) | JPH0764809B2 (sv) |
KR (2) | KR920008166B1 (sv) |
CN (1) | CN1023007C (sv) |
AT (1) | ATE96783T1 (sv) |
AU (1) | AU614224B2 (sv) |
BA (1) | BA98300A (sv) |
CA (1) | CA2012295C (sv) |
CL (1) | CL2003002756A1 (sv) |
CY (2) | CY1812A (sv) |
CZ (1) | CZ280053B6 (sv) |
DD (1) | DD292911A5 (sv) |
DE (2) | DE122005000022I2 (sv) |
DK (1) | DK0388054T3 (sv) |
EG (1) | EG18951A (sv) |
ES (1) | ES2060020T3 (sv) |
FI (1) | FI95573C (sv) |
GB (1) | GB8906166D0 (sv) |
HK (1) | HK130294A (sv) |
HU (2) | HU217433B (sv) |
IE (1) | IE62515B1 (sv) |
IL (1) | IL93694A (sv) |
LU (1) | LU91161I2 (sv) |
MX (1) | MX9319890A (sv) |
MY (1) | MY105527A (sv) |
NL (1) | NL300191I2 (sv) |
NO (2) | NO176316C (sv) |
NZ (1) | NZ232958A (sv) |
PL (1) | PL164136B1 (sv) |
PT (1) | PT93443B (sv) |
RU (2) | RU1833374C (sv) |
SG (1) | SG143394G (sv) |
SK (1) | SK129590A3 (sv) |
UA (1) | UA18263A (sv) |
YU (1) | YU47587B (sv) |
ZA (1) | ZA901982B (sv) |
Families Citing this family (68)
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GB8825505D0 (en) * | 1988-11-01 | 1988-12-07 | Pfizer Ltd | Therapeutic agents |
US5932594A (en) * | 1988-11-01 | 1999-08-03 | Pfizer, Inc. | Muscarinic receptor antagonists |
GB8928042D0 (en) * | 1989-12-12 | 1990-02-14 | Pfizer Ltd | Muscarinic receptor antagonists |
US5607950A (en) * | 1990-01-06 | 1997-03-04 | Pfizer Inc. | Muscarinic receptor antagonists |
US5486527A (en) * | 1990-01-06 | 1996-01-23 | Pfizer Inc. | Anticholinergic agents |
ATE201677T1 (de) * | 1992-04-23 | 2001-06-15 | Merrell Pharma Inc | 4-imidomethyl-1-(2'-phenyl-2-oxoethyl)-piperidi e als serotonin-5ht2-antagonisten, ihre herstellung und therapeutische anwendung |
GB9400600D0 (en) * | 1994-01-14 | 1994-03-09 | Pfizer Ltd | Treatment of motion seckness |
US5639763A (en) * | 1994-03-01 | 1997-06-17 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines |
US6017931A (en) * | 1994-03-01 | 2000-01-25 | Fmc Corporation | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines |
US5656661A (en) * | 1994-07-27 | 1997-08-12 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
AU704085B2 (en) * | 1994-07-27 | 1999-04-15 | Vanderbilt University | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
GB9518953D0 (en) * | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
HUP0001118A3 (en) * | 1996-12-02 | 2001-06-28 | Kyorin Seiyaku Kk | N-substituted pyrrolidine derivatives, process for preparing the same and pharmaceutical compositions containing them |
US6131129A (en) * | 1997-07-30 | 2000-10-10 | Sony Corporation Of Japan | Computer system within an AV/C based media changer subunit providing a standarized command set |
US6693202B1 (en) | 1999-02-16 | 2004-02-17 | Theravance, Inc. | Muscarinic receptor antagonists |
IL141235A (en) * | 2000-02-09 | 2012-04-30 | Novartis Int Pharm Ltd | Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia |
US6653339B2 (en) | 2001-08-15 | 2003-11-25 | Pfizer Inc. | Method of treating irritable bowel syndrome |
DK1461306T3 (da) * | 2001-10-26 | 2009-03-09 | Pharmacia & Upjohn Co Llc | Kvaternære ammoniumforbindelser og deres anvendelse som antimuscarin-midler |
SE0103668D0 (sv) * | 2001-11-02 | 2001-11-02 | Astrazeneca Ab | Method for the treatment of overactive blader |
CA2464217A1 (en) * | 2001-11-05 | 2003-05-15 | Pharmacia & Upjohn Company | Antimuscarinic aerosol |
GB0129962D0 (en) * | 2001-12-14 | 2002-02-06 | Pfizer Ltd | Method of treatment |
GB0207104D0 (en) | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
AU2002345266B2 (en) | 2002-07-08 | 2009-07-02 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
WO2004014853A1 (en) | 2002-07-31 | 2004-02-19 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
AU2002321711A1 (en) | 2002-08-09 | 2004-02-25 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives useful as muscarinic receptor antagonist |
US7288562B2 (en) | 2002-08-23 | 2007-10-30 | Ranbaxy Laboratories Limited | Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists |
TW200412945A (en) * | 2002-10-25 | 2004-08-01 | Upjohn Co | Quaternary ammonium compounds |
TW200800953A (en) * | 2002-10-30 | 2008-01-01 | Theravance Inc | Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine |
US7232835B2 (en) | 2002-12-10 | 2007-06-19 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists |
WO2004056811A1 (en) | 2002-12-23 | 2004-07-08 | Ranbaxy Laboratories Limited | Flavaxate derivatives as muscarinic receptor antagonists |
WO2004056767A1 (en) * | 2002-12-23 | 2004-07-08 | Ranbaxy Laboratories Limited | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists |
US7488748B2 (en) | 2003-01-28 | 2009-02-10 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
WO2004089892A2 (en) * | 2003-04-01 | 2004-10-21 | Theravance, Inc. | Diarylmethyl and related compounds having beta2 andrenergic receptor agonist and muscarinic receptor antagonist activity |
WO2004089898A1 (en) | 2003-04-09 | 2004-10-21 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
EP1615634B1 (en) | 2003-04-10 | 2007-05-16 | Ranbaxy Laboratories, Ltd. | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
EP1615887A1 (en) | 2003-04-10 | 2006-01-18 | Ranbaxy Laboratories, Ltd. | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
BRPI0409302A (pt) | 2003-04-11 | 2006-04-11 | Ranbaxy Lab Ltd | derivados azabiciclo como antagonistas de recetores muscarìnicos, método para sua preparação e composição farmacêutica contendo os mesmos |
WO2004091597A2 (en) * | 2003-04-15 | 2004-10-28 | Pharmacia & Upjohn Company Llc | Method of treating irritable bowel syndrome (ibs) |
JP2006523676A (ja) * | 2003-04-15 | 2006-10-19 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 第四級アンモニウム化合物と、その抗ムスカリン性剤としての使用 |
MXPA05011225A (es) * | 2003-04-18 | 2005-12-14 | Pharmacia & Upjohn Co Llc | Politerapias. |
TW200510298A (en) | 2003-06-13 | 2005-03-16 | Theravance Inc | Substituted pyrrolidine and related compounds |
EP1644356A1 (en) | 2003-07-11 | 2006-04-12 | Theravance, Inc. | Substituted 4-amino-1-benzylpiperidine compounds |
US7071224B2 (en) * | 2004-03-11 | 2006-07-04 | Theravance, Inc. | Diphenylmethyl compounds useful as muscarinic receptor antagonists |
JP2007528418A (ja) * | 2004-03-11 | 2007-10-11 | セラヴァンス, インコーポレーテッド | ムスカリンレセプターアンタゴニストとしての有用なジフェニルメチル化合物 |
EP1746998A1 (en) * | 2004-03-22 | 2007-01-31 | Ranbaxy Laboratories, Ltd. | Combination therapy for lower urinary tract symptoms |
BRPI0617674A2 (pt) | 2005-10-19 | 2011-08-02 | Ranbaxy Lab Ltd | composições farmacêuticas e seus usos |
CA2626715A1 (en) * | 2005-12-27 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Processes for preparing darifenacin hydrobromide |
AR062676A1 (es) | 2006-09-07 | 2008-11-26 | Medichem Sa | Procedimiento mejorado para preparar compuestos de pirrolidina 1,3-disustituidas |
WO2008076269A2 (en) * | 2006-12-13 | 2008-06-26 | Gilead Sciences, Inc. | MONOPHOSPHATES AS MUTUAL PRODRUGS OF MUSCARINIC RECEPTOR ANTAGONISTS AND β-AGONISTS FOR THE TREATMENT OF COPD AND CHRONIC BRONCHITIS |
EP2109601A2 (en) * | 2007-01-05 | 2009-10-21 | Dr. Reddy's Laboratories Ltd. | Preparation of darifenacin and its salts |
CN101616893B (zh) * | 2007-02-23 | 2014-01-29 | 施万制药 | 用作毒蕈碱受体拮抗剂的季铵二苯基甲基化合物 |
WO2008126106A2 (en) * | 2007-04-16 | 2008-10-23 | Manne Satyanarayana Reddy | Novel and improved processes for the preparation of intermediates of darifenacin, darifenacin and its pharmaceutically acceptable salts |
US20100204296A1 (en) * | 2007-06-08 | 2010-08-12 | Actavis Group Ptc Ehf | Novel Polymorphs of Darifenacin Free Base and its Hydrobromide Salt |
WO2008152497A1 (en) * | 2007-06-15 | 2008-12-18 | Medichem, S.A. | Method for determining enantiomeric purity of darifenacin and intermediates |
WO2009006413A1 (en) * | 2007-06-30 | 2009-01-08 | Auspex Pharmaceuticals, Inc. | Substituted pyrrolidines |
US20090018346A1 (en) * | 2007-07-13 | 2009-01-15 | Medichem, S.A. | Amorphous Form Of Darifenacin Hydrobromide And Processes For The Preparation Thereof |
CZ200845A3 (cs) * | 2008-01-28 | 2009-09-02 | Zentiva, A. S. | Zpusob prípravy Darifenacinu |
WO2009125430A2 (en) * | 2008-03-17 | 2009-10-15 | Matrix Laboratoires Limited | Improved process for producing darifenacin |
CN101983187A (zh) * | 2008-04-02 | 2011-03-02 | 株式会社钟化 | (s)-3-(1-氰基-1,1-二苯基甲基)吡咯烷的制备方法 |
US20110144354A1 (en) * | 2008-09-22 | 2011-06-16 | Watson Pharma Private Limited | Process for Preparation of Darifenacin and Intermediates Used in the Process |
EP2236509A1 (en) | 2009-04-01 | 2010-10-06 | Ragactives, S.L. | Method for obtaining 1,3-difunctionalized pyrrolidine derivatives |
WO2010131054A1 (en) | 2009-05-15 | 2010-11-18 | Bradford Pharma Limited | Redox drug derivatives |
WO2011070419A1 (en) | 2009-12-10 | 2011-06-16 | Aurobindo Pharma Limited | An improved process for the preparation of darifenacin hydrobromide |
WO2011137054A1 (en) | 2010-04-30 | 2011-11-03 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
CN101857581A (zh) * | 2010-06-22 | 2010-10-13 | 浙江美诺华药物化学有限公司 | 一种制备达非那新中间体5-(2-溴乙基)-2,3-二氢-1-苯并呋喃的方法 |
WO2011161504A1 (en) | 2010-06-23 | 2011-12-29 | Micro Labs Limited | Extended release formulations containing darifenacin or pharmaceutically acceptable salts thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1057145A (en) * | 1963-08-16 | 1967-02-01 | Bellon Labor Sa Roger | Phenylcyclohexylacetonitrile derivatives |
US4002766A (en) * | 1974-12-26 | 1977-01-11 | A. H. Robins Company, Incorporated | Antiarrhythmia methods |
US4242261A (en) * | 1979-07-19 | 1980-12-30 | A. H. Robins Company, Inc. | Production of methylene-cycloamines |
IL76583A (en) * | 1984-10-19 | 1988-08-31 | Robins Co Inc A H | 1-(aminoalkyl)-alpha'alpha-diaryl pyrrolidinyl,piperidino and homopiperidino acetamides and acetonitriles and pharmaceutical compositions containing them |
US4594343A (en) * | 1984-10-19 | 1986-06-10 | Shanklin Jr James R | 1-[(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
EP0235463A3 (en) * | 1985-12-20 | 1990-01-17 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents |
IL78939A (en) * | 1986-01-17 | 1990-04-29 | Robins Co Inc A H | Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds |
-
1989
- 1989-03-17 GB GB898906166A patent/GB8906166D0/en active Pending
-
1990
- 1990-03-02 AT AT90302269T patent/ATE96783T1/de active
- 1990-03-02 DE DE200512000022 patent/DE122005000022I2/de active Active
- 1990-03-02 ES ES90302269T patent/ES2060020T3/es not_active Expired - Lifetime
- 1990-03-02 DK DK90302269.7T patent/DK0388054T3/da active
- 1990-03-02 EP EP90302269A patent/EP0388054B1/en not_active Expired - Lifetime
- 1990-03-02 DE DE90302269T patent/DE69004302T2/de not_active Expired - Lifetime
- 1990-03-09 IL IL9369490A patent/IL93694A/en not_active IP Right Cessation
- 1990-03-13 US US07493068 patent/US5096890B1/en not_active Expired - Lifetime
- 1990-03-14 MX MX1989090A patent/MX9319890A/es unknown
- 1990-03-14 HU HU580/90A patent/HU217433B/hu unknown
- 1990-03-15 CA CA002012295A patent/CA2012295C/en not_active Expired - Lifetime
- 1990-03-15 PT PT93443A patent/PT93443B/pt not_active IP Right Cessation
- 1990-03-15 ZA ZA901982A patent/ZA901982B/xx unknown
- 1990-03-15 JP JP2065521A patent/JPH0764809B2/ja not_active Expired - Lifetime
- 1990-03-15 KR KR1019900003453A patent/KR920008166B1/ko not_active IP Right Cessation
- 1990-03-15 EG EG17090A patent/EG18951A/xx active
- 1990-03-16 MY MYPI90000416A patent/MY105527A/en unknown
- 1990-03-16 DD DD90338829A patent/DD292911A5/de not_active IP Right Cessation
- 1990-03-16 SK SK1295-90A patent/SK129590A3/sk not_active IP Right Cessation
- 1990-03-16 RU SU904743599A patent/RU1833374C/ru active
- 1990-03-16 AU AU51402/90A patent/AU614224B2/en not_active Expired
- 1990-03-16 IE IE95590A patent/IE62515B1/en not_active IP Right Cessation
- 1990-03-16 NZ NZ232958A patent/NZ232958A/en unknown
- 1990-03-16 PL PL90284342A patent/PL164136B1/pl unknown
- 1990-03-16 FI FI901333A patent/FI95573C/sv active Protection Beyond IP Right Term
- 1990-03-16 YU YU52790A patent/YU47587B/sh unknown
- 1990-03-16 NO NO901241A patent/NO176316C/no not_active IP Right Cessation
- 1990-03-16 UA UA4743599A patent/UA18263A/uk unknown
- 1990-03-16 CZ CS901295A patent/CZ280053B6/cs not_active IP Right Cessation
- 1990-03-17 CN CN90101543A patent/CN1023007C/zh not_active Expired - Lifetime
-
1991
- 1991-03-13 RU SU914894696A patent/RU2015965C1/ru active
-
1992
- 1992-08-12 KR KR1019920014485A patent/KR960015142B1/ko not_active IP Right Cessation
-
1994
- 1994-09-26 JP JP6229807A patent/JPH07149640A/ja active Pending
- 1994-10-03 SG SG143394A patent/SG143394G/en unknown
- 1994-11-24 HK HK130294A patent/HK130294A/xx not_active IP Right Cessation
-
1995
- 1995-06-28 HU HU95P/P00505P patent/HU211640A9/hu active Protection Beyond IP Right Term
- 1995-10-20 CY CY181295A patent/CY1812A/xx unknown
-
1998
- 1998-03-30 BA BA980300A patent/BA98300A/bs unknown
-
2003
- 2003-12-26 CL CL200302756A patent/CL2003002756A1/es unknown
-
2005
- 2005-04-01 NO NO2005008C patent/NO2005008I2/no unknown
- 2005-04-04 CY CY2005005C patent/CY2005005I1/el unknown
- 2005-04-08 NL NL300191C patent/NL300191I2/nl unknown
- 2005-04-11 LU LU91161C patent/LU91161I2/fr unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
FG | Patent granted |
Owner name: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD |
|
SPCF | Supplementary protection certificate application filed |
Spc suppl protection certif: L20050008 |
|
SPCG | Supplementary protection certificate granted |
Spc suppl protection certif: NUMBER:224 |