FI944169A - Menetelmä beta-fenyyli-isoseriinin ja sen analogien valmistamiseksi - Google Patents

Menetelmä beta-fenyyli-isoseriinin ja sen analogien valmistamiseksi Download PDF

Info

Publication number
FI944169A
FI944169A FI944169A FI944169A FI944169A FI 944169 A FI944169 A FI 944169A FI 944169 A FI944169 A FI 944169A FI 944169 A FI944169 A FI 944169A FI 944169 A FI944169 A FI 944169A
Authority
FI
Finland
Prior art keywords
pct
general formula
phenylisoserine
beta
date sep
Prior art date
Application number
FI944169A
Other languages
English (en)
Swedish (sv)
Other versions
FI113640B (fi
FI944169A0 (fi
Inventor
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI944169A0 publication Critical patent/FI944169A0/fi
Publication of FI944169A publication Critical patent/FI944169A/fi
Application granted granted Critical
Publication of FI113640B publication Critical patent/FI113640B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI944169A 1992-03-10 1994-09-09 Menetelmä beta-fenyyli-isoseriinin ja sen analogien valmistamiseksi, menetelmässä käytettävän lähtöaineen valmistus ja lähtöaine FI113640B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9202821A FR2688499B1 (fr) 1992-03-10 1992-03-10 Procede de preparation de la beta-phenylisoserine et de ses analogues.
FR9202821 1992-03-10
FR9300224 1993-03-08
PCT/FR1993/000224 WO1993017997A1 (fr) 1992-03-10 1993-03-08 PROCEDE DE PREPARATION DE LA β-PHENYLISOSERINE ET DE SES ANALOGUES

Publications (3)

Publication Number Publication Date
FI944169A0 FI944169A0 (fi) 1994-09-09
FI944169A true FI944169A (fi) 1994-09-09
FI113640B FI113640B (fi) 2004-05-31

Family

ID=9427518

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944169A FI113640B (fi) 1992-03-10 1994-09-09 Menetelmä beta-fenyyli-isoseriinin ja sen analogien valmistamiseksi, menetelmässä käytettävän lähtöaineen valmistus ja lähtöaine

Country Status (25)

Country Link
US (2) US5608102A (fi)
EP (1) EP0630365B1 (fi)
JP (1) JP3278768B2 (fi)
KR (1) KR100272650B1 (fi)
AT (1) ATE159512T1 (fi)
AU (1) AU667886B2 (fi)
CA (1) CA2130333C (fi)
CZ (1) CZ283613B6 (fi)
DE (1) DE69314779T2 (fi)
DK (1) DK0630365T3 (fi)
ES (1) ES2109509T3 (fi)
FI (1) FI113640B (fi)
FR (1) FR2688499B1 (fi)
GE (1) GEP19981430B (fi)
GR (1) GR3025117T3 (fi)
HU (1) HU213621B (fi)
MX (1) MX9301268A (fi)
NO (1) NO304515B1 (fi)
NZ (1) NZ249899A (fi)
PL (1) PL171551B1 (fi)
RU (1) RU2103258C1 (fi)
SK (1) SK281297B6 (fi)
TW (1) TW252971B (fi)
WO (1) WO1993017997A1 (fi)
ZA (1) ZA931677B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9520078B (sl) * 1994-07-26 1998-12-31 Indena S.P.A. Polsintetski taksani z antitumorsko aktivnostjo
US6765015B2 (en) * 1995-12-13 2004-07-20 Xechem International, Inc. Halogenated paclitaxel derivatives
AU739303B2 (en) 1997-08-21 2001-10-11 Florida State University Method for the synthesis of taxanes
WO1999025334A1 (en) * 1997-11-19 1999-05-27 Xechem International, Inc. Halogenated paclitaxel derivatives
ITMI991483A1 (it) 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
JP2002080435A (ja) * 2000-06-26 2002-03-19 Kanegafuchi Chem Ind Co Ltd ３−アミノ−２−ヒドロキシプロピオン酸誘導体の製造法
JP4142444B2 (ja) 2001-03-07 2008-09-03 第一三共株式会社 ２−アゼチジノン誘導体の製造方法
SI1961735T1 (sl) * 2007-02-22 2010-01-29 Indena Spa Postopek za pripravo acetatne soli (2r,3s)-3-fenilizoserin-metilestra
ES2389518T3 (es) 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
CN102408356A (zh) * 2011-09-28 2012-04-11 北京东方协和医药生物技术有限公司 一种多西他赛手性侧链中间体的制备方法
KR101900584B1 (ko) * 2014-02-03 2018-09-19 콰드리가 바이오사이언시스 인코포레이티드 화학치료제로서의 베타-치환된 베타-아미노산 및 유사체
CN111100026A (zh) * 2019-12-30 2020-05-05 重庆市碚圣医药科技股份有限公司 一种紫杉醇恶唑环侧链中间体的制备方法
CN112574134A (zh) * 2020-12-30 2021-03-30 重庆市碚圣医药科技股份有限公司 一种多西紫杉醇侧链的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5304670A (en) * 1989-08-23 1994-04-19 Centre National De La Recherche Scientifique Process for the enantioselective preparation of phenylisoserine derivatives
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
US5294737A (en) * 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom

Also Published As

Publication number Publication date
NO943280D0 (no) 1994-09-05
DE69314779D1 (de) 1997-11-27
WO1993017997A1 (fr) 1993-09-16
ATE159512T1 (de) 1997-11-15
CZ283613B6 (cs) 1998-05-13
GEP19981430B (en) 1998-10-30
KR950700234A (ko) 1995-01-16
RU2103258C1 (ru) 1998-01-27
DK0630365T3 (da) 1998-03-02
GR3025117T3 (en) 1998-01-30
HU213621B (en) 1997-08-28
FI113640B (fi) 2004-05-31
EP0630365A1 (fr) 1994-12-28
SK281297B6 (sk) 2001-02-12
FR2688499A1 (fr) 1993-09-17
CA2130333A1 (fr) 1993-09-16
EP0630365B1 (fr) 1997-10-22
NO943280L (no) 1994-09-05
FI944169A0 (fi) 1994-09-09
RU94045799A (ru) 1996-07-20
KR100272650B1 (ko) 2000-11-15
FR2688499B1 (fr) 1994-05-06
MX9301268A (es) 1993-09-01
US5608102A (en) 1997-03-04
HUT68540A (en) 1995-06-28
ES2109509T3 (es) 1998-01-16
CA2130333C (fr) 2002-11-26
NO304515B1 (no) 1999-01-04
HU9402590D0 (en) 1994-11-28
AU667886B2 (en) 1996-04-18
JPH07504425A (ja) 1995-05-18
AU3755793A (en) 1993-10-05
NZ249899A (en) 1996-01-26
CZ218594A3 (en) 1995-11-15
TW252971B (fi) 1995-08-01
ZA931677B (en) 1993-10-06
US5763628A (en) 1998-06-09
JP3278768B2 (ja) 2002-04-30
PL171551B1 (pl) 1997-05-30
SK108594A3 (en) 1995-02-08
DE69314779T2 (de) 1998-02-26

Similar Documents

Publication Publication Date Title
FI944169A0 (fi) Menetelmä beta-fenyyli-isoseriinin ja sen analogien valmistamiseksi
EP0339237A3 (en) Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them
ES2010114A6 (es) Procedimiento de preparacion de derivados de los acidos 1,4-dihidro-4-oxoquinolein-3-carboxilicos.
FI954898A0 (fi) Vesiliukoiset kamptotesiinijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineina
AU699480B2 (en) 2,2-Dichloroalkane carboxylic acids, processes for their production and pharmaceutical agents containing these
FI870589A0 (fi) Ny farmaceutisk sammansaettning och foerfarande foer framstaellning av den.
ATE165827T1 (de) Herstellung von n-acetylneuraminsäure-derivaten
ZA952771B (en) Novel compound
ATE246515T1 (de) Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac
AU5644296A (en) Novel heterocyclic chemistry
BR9610175A (pt) Composto processo de preparação do composto composição farmacêutica e utilização do composto
HU886767D0 (en) Process for the preparation of new 20,21-dinor-eburnamenine derivatives, new intermediates thereof, as well as pharmaceutical compositions containing said compounds as active ingredients
BR9306870A (pt) Derivados farmacologicamente ativos de (aminometila terciária) - benzenometanol
ZA937317B (en) Process for the stereoselective preparation of a beta-phenylisoserine derivative and its use for the preparation of taxane derivatives
PT1214315E (pt) Esteres derivados do acido 1,4-di-hidropiridina-5-carboxilico e metodo para a sua preparacao
AU1459192A (en) Aminoacyl derivatives of gem-diphosphonic acids, a process for the preparation thereof and pharmaceutical compositions containing them
IT1247508B (it) Composizioni farmaceutiche contenenti l'estere 4-(2 metilamminoetil)- 1,2- fenilenicodell`acido 2-metilpropanoico per il trattamento della neurootticopatia glaucomatosa

Legal Events

Date Code Title Description
MA Patent expired