FI931826A - Foerfarande foer framstaellning av en virussaeker, hoegt renad faktor viii - Google Patents

Foerfarande foer framstaellning av en virussaeker, hoegt renad faktor viii Download PDF

Info

Publication number
FI931826A
FI931826A FI931826A FI931826A FI931826A FI 931826 A FI931826 A FI 931826A FI 931826 A FI931826 A FI 931826A FI 931826 A FI931826 A FI 931826A FI 931826 A FI931826 A FI 931826A
Authority
FI
Finland
Prior art keywords
factor viii
virussaeker
renad
hoegt
formulation
Prior art date
Application number
FI931826A
Other languages
English (en)
Other versions
FI931826A0 (fi
FI106468B (fi
Inventor
Johann Eibl
Friedrich Elsinger
Herbert Gritsch
Yendra Linnau
Otto Schwarz
Peter Turecek
Guenther Woeber
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3501200&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI931826(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of FI931826A0 publication Critical patent/FI931826A0/fi
Publication of FI931826A publication Critical patent/FI931826A/fi
Application granted granted Critical
Publication of FI106468B publication Critical patent/FI106468B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FI931826A 1992-04-24 1993-04-22 Menetelmä virusturvallisen, erittäin puhtaan tekijä VIII:n valmistamiseksi FI106468B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT84992 1992-04-24
AT0084992A AT399818B (de) 1992-04-24 1992-04-24 Verfahren zur herstellung einer hochgereinigten virussicheren faktor viii-präparation

Publications (3)

Publication Number Publication Date
FI931826A0 FI931826A0 (fi) 1993-04-22
FI931826A true FI931826A (fi) 1993-10-25
FI106468B FI106468B (fi) 2001-02-15

Family

ID=3501200

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931826A FI106468B (fi) 1992-04-24 1993-04-22 Menetelmä virusturvallisen, erittäin puhtaan tekijä VIII:n valmistamiseksi

Country Status (18)

Country Link
US (1) US5410022A (fi)
EP (1) EP0567448B2 (fi)
JP (1) JP2511631B2 (fi)
AT (2) AT399818B (fi)
AU (1) AU659301B2 (fi)
BR (1) BR9301641A (fi)
CA (1) CA2094347C (fi)
CZ (1) CZ279979B6 (fi)
DE (1) DE59308628D1 (fi)
DK (1) DK0567448T4 (fi)
ES (1) ES2117703T5 (fi)
FI (1) FI106468B (fi)
HU (1) HU210632B (fi)
MX (1) MX9302279A (fi)
NO (1) NO307465B1 (fi)
PL (1) PL172462B1 (fi)
SK (1) SK279750B6 (fi)
ZA (1) ZA932843B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6653094A (en) * 1992-12-16 1994-07-04 Immuno Aktiengesellschaft Process for preparing a virus-safe biological composition
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
DE4325872C1 (de) * 1993-08-02 1994-08-04 Immuno Ag Virusinaktivierte Faktor Xa-Präparation
AT402788B (de) * 1993-08-03 1997-08-25 Immuno Ag Virussichere blutgerinnungsfaktor xiii-präparation
DE4337573C1 (de) * 1993-11-04 1995-05-18 Octapharma Ag Verfahren zur Herstellung einer virusinaktivierten Faktor VIII enthaltenden Fraktion mittels chromatographischer Methoden
DE4407837C1 (de) * 1994-03-09 1995-08-17 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem alpha¶1¶-Antitrypsin mittels Anionenaustauscher-Chromatographie
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
DE19623293C2 (de) * 1996-06-11 1998-10-22 Biotest Pharma Gmbh Nicht-immunogene Faktor VIII-enthaltende Zusammensetzung und ein Verfahren zu ihrer Herstellung
AT404358B (de) 1997-02-04 1998-11-25 Immuno Ag Verfahren zur chromatographischen reinigung bzw. fraktionierung von von willebrand-faktor aus einem vwf-hältigen ausgangsmaterial
JP5149470B2 (ja) 1999-02-22 2013-02-20 バクスター・インターナショナル・インコーポレイテッド 新規のアルブミンを含有していない第ｖｉｉｉ因子処方物
US20040117862A1 (en) * 2002-03-11 2004-06-17 Cooper Julian D. Production of high levels of transgenic factor VII with engineered stability and its therapeutic uses
JP2008514240A (ja) * 2004-10-01 2008-05-08 インヴィトロジェン コーポレーション 生体分子のインビトロ合成用の供給バッファー、系、及び方法
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
CN101967188B (zh) * 2010-11-08 2012-11-28 江西博雅生物制药股份有限公司 一种人凝血因子ⅷ的制备工艺
CN107073084B (zh) * 2014-11-05 2022-03-25 雅培制药股份有限公司 用于生产具有改善的安全特性的具有脂肪酶活性的组合物和适用于药物用途的组合物的方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
AT350726B (de) * 1976-08-30 1979-06-11 Immuno Ag Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma
FR2435832A1 (fr) * 1978-07-21 1980-04-04 Alsthom Cgee Dispositif de connexion electrique
US4250139A (en) * 1979-02-01 1981-02-10 Collagen Corporation Microwave sterilization of dry protein
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
EP0035204B2 (en) * 1980-03-05 1991-05-22 Miles Inc. Pasteurized therapeutically active protein compositions
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
DE3173208D1 (en) * 1980-10-06 1986-01-23 Edward Shanbrom Method of reducing undesirable activities of biological and pharmaceutical products
DE3043857A1 (de) * 1980-11-21 1982-07-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ii und vii
DE3045153A1 (de) * 1980-11-29 1982-07-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ix und x
US4495278A (en) * 1981-04-27 1985-01-22 Baxter Travenol Laboratories, Inc. Process for making novel blood clotting enzyme compositions
US4456590B2 (en) * 1981-11-02 1989-05-30 Heat treatment of lyphilized blood clotting factor viii concentrate
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US4379085A (en) * 1982-05-14 1983-04-05 American National Red Cross Heat stabilization of plasma proteins
US4511556A (en) * 1982-06-10 1985-04-16 The United States Of America As Represented By The Department Of Health And Human Services Inactivation of a lipid virus
JPS59134730A (ja) * 1983-01-20 1984-08-02 Green Cross Corp:The 血液凝固第８因子の加熱処理法
CA1213827A (en) * 1983-04-29 1986-11-12 Ricardo H. Landaburu Process for pasteurizing fibronectin
DE3473407D1 (en) * 1983-05-02 1988-09-22 Immuno Ag Method of inactivating pathogens
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
JPS6054287B2 (ja) * 1983-10-19 1985-11-29 株式会社ミドリ十字 血漿蛋白の加熱処理方法
US4490361A (en) * 1983-12-02 1984-12-25 Alpha Therapeutic Corporation Virus inactivating heat treatment of plasma fractions
AT389815B (de) * 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
US5043428A (en) * 1984-08-31 1991-08-27 Behringwerke Aktiengesellschaft Pasteurized, isoagglutinin-free factor VIII preparation and a process for its production
DE3432083A1 (de) * 1984-08-31 1986-03-06 Behringwerke Ag, 3550 Marburg Pasteurisierte, isoagglutininfreie faktor viii-praeparation und verfahren zu ihrer herstellung
JPH0669961B2 (ja) * 1984-09-25 1994-09-07 株式会社ミドリ十字 免疫グロブリンの加熱処理方法
JPH0825902B2 (ja) * 1985-02-21 1996-03-13 株式会社ミドリ十字 γ−グロブリンの加熱処理方法
US4673733A (en) * 1985-04-11 1987-06-16 Sudhish Chandra Treatment of biological and pharmaceutical products adsorbed on a solid phase with virus and pyrogen inactivating agents
AT391808B (de) * 1986-11-03 1990-12-10 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion
AT388501B (de) * 1987-02-12 1989-07-25 Immuno Ag Verfahren zur herstellung von parenteral verabreichbaren blutprodukten
AU2251288A (en) * 1987-05-15 1988-12-06 Alan I. Rubinstein Sequential improved method for treatment of human blood- clotting factor products
IL86417A (en) * 1987-05-22 1992-09-06 Armour Pharma Process for the inactivation of pathogens in biological or pharmaceutical material by mixing with aqueous solution containing a sugar(alcohol)and neutral salts as stabilizers
AT391809B (de) * 1988-01-12 1990-12-10 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutplasmaprodukten
FR2630115B1 (fr) * 1988-04-14 1994-10-28 Merieux Inst Procede de stabilisation des solutions d'albumine humaine et solution obtenue
DE3878227D1 (de) * 1988-05-27 1993-03-18 Centre Regional De Transfusion Verfahren zur herstellung eines hochreinen, virusfreien antihaemophiliefaktors mittels chromatographie.
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
AT390801B (de) * 1988-07-28 1990-07-10 Immuno Ag Verfahren zur herstellung von lys-plasminogen
EP0367840B1 (de) * 1988-11-05 1993-02-03 Octapharma AG Verfahren zur Herstellung eines hochreinen, nicht infektiösen Antihämophiliefaktors mittels Chromatographie
US5156973A (en) * 1988-11-23 1992-10-20 Edward Shanbrom Antiviral blood sampling process and apparatus
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
DE69011136T3 (de) * 1989-01-13 2003-10-23 Mitsubishi Pharma Corp Verfahren zur Herstellung einer Protein enthaltenden Zusammensetzung.
DE69027187T2 (de) * 1989-06-15 1996-10-31 Rorer Int Overseas Verfahren zur inaktivierung von viren in mit viren verunreinigten pharmazeutischen zusammensetzungen
IE73210B1 (en) * 1990-01-24 1997-05-07 Warner Lambert Co Process for the production of thrombin and high purity thrombin preparation thereby obtained
US5217737A (en) * 1991-05-20 1993-06-08 Abbott Laboratories Plastic containers capable of surviving sterilization
AT402891B (de) * 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.
FR2681867B1 (fr) * 1991-09-26 1993-12-31 Pasteur Merieux Serums Vaccins Procede de purification du facteur viii et preparations obtenues.
AT398079B (de) * 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
FR2841484B1 (fr) * 2002-06-26 2004-09-10 Boucq De Beaudignies Ghisla Le Dispositif et procede de filtration de l'air et des gaz avec regeneration des particules captees

Also Published As

Publication number Publication date
HU210632B (en) 1995-06-28
EP0567448B2 (de) 2005-01-05
JPH069694A (ja) 1994-01-18
ZA932843B (en) 1993-11-23
JP2511631B2 (ja) 1996-07-03
DK0567448T3 (da) 1999-03-22
ES2117703T5 (es) 2005-07-16
SK39193A3 (en) 1993-11-10
BR9301641A (pt) 1993-10-26
PL298670A1 (en) 1994-04-05
HUT64777A (en) 1994-02-28
EP0567448A1 (de) 1993-10-27
CZ69293A3 (en) 1993-12-15
NO931476D0 (no) 1993-04-22
SK279750B6 (sk) 1999-03-12
AU3687593A (en) 1993-10-28
ATE166881T1 (de) 1998-06-15
ES2117703T3 (es) 1998-08-16
ATA84992A (de) 1994-12-15
DK0567448T4 (da) 2005-05-02
CA2094347A1 (en) 1993-10-25
FI931826A0 (fi) 1993-04-22
MX9302279A (es) 1994-08-31
FI106468B (fi) 2001-02-15
AT399818B (de) 1995-07-25
US5410022A (en) 1995-04-25
EP0567448B1 (de) 1998-06-03
PL172462B1 (pl) 1997-09-30
HU9301038D0 (en) 1993-06-28
CZ279979B6 (cs) 1995-09-13
CA2094347C (en) 2002-06-25
NO931476L (no) 1993-10-25
NO307465B1 (no) 2000-04-10
AU659301B2 (en) 1995-05-11
DE59308628D1 (de) 1998-07-09

Similar Documents

Publication Publication Date Title
FI931826A0 (fi) Foerfarande foer framstaellning av en virussaeker, hoegt renad faktor viii
FI942573A (fi) Koostumus, joka käsittää hyytymistekijä VIII -formuloinnin, sen valmistusmenetelmä ja pinta-aktiivisen aineen käyttö stabilointiaineena
DK140996A (da) Fremgangsmåde til fremstilling af 2,3,4,5-tetraflour-6-alkyl-benzoesyreforbindelser
FI920023A0 (fi) Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
ZA928162B (en) Antibodies in immunosuppression.
HUT71550A (en) Pharmaceutical agents containing quinuclidine, piperidine or azanorbornane derivatives for treatment of emesis
ATE130009T1 (de) Antitumor-aminosäuren und peptid-derivate von 1,4-bis((aminoalkyl und hydroxyaminoalkyl)amino>5,8- dihydroxyanthraquinonen.
CA2096888A1 (en) Process for the inactivation of viruses in preparations of proteins
ATE308616T1 (de) Rantes mutanten und deren therapeutische verwendungen
ZA932326B (en) Novel cardioprotective agents
AU2629792A (en) Process for the purification of streptolysin 0, intact streptolysin 0 obtained by this process and its use
ATE157959T1 (de) Indanderivate
ATE159756T1 (de) Reinigung von faktor xiii
IL103856A0 (en) Aminoalkyl-substituted 5,6-dihydro-dibenz(b,e)azepin-6,11-dione-11-oximes,their preparation and pharmaceutical compositions containing them
DE69305883D1 (de) Verfahren zur Herstellung von 2,6-Dimethylnaphthalin
DE59307374D1 (de) Verfahren zur Herstellung von 5-Halogen-2-(1-anthrachinonylamino)benzoesäuren und 4'-Halogen-2,1(N)-anthrachinonyl-1',2'(N)-benzacridonen
FI921844A0 (fi) Menetelmä 2,6-di-isopropyylifenolin puhdistamiseksi
RU93050545A (ru) Пиперацин-2,3-дионы как регуляторы роста растений