CA2096888A1 - Process for the inactivation of viruses in preparations of proteins - Google Patents

Process for the inactivation of viruses in preparations of proteins

Info

Publication number
CA2096888A1
CA2096888A1 CA002096888A CA2096888A CA2096888A1 CA 2096888 A1 CA2096888 A1 CA 2096888A1 CA 002096888 A CA002096888 A CA 002096888A CA 2096888 A CA2096888 A CA 2096888A CA 2096888 A1 CA2096888 A1 CA 2096888A1
Authority
CA
Canada
Prior art keywords
inactivation
viruses
proteins
preparations
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002096888A
Other languages
French (fr)
Other versions
CA2096888C (en
Inventor
Herman Keuper
Walter Matzmorr
Wilfried Freudenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Herman Keuper
Walter Matzmorr
Wilfried Freudenberg
Behringwerke Aktiengesellschaft
Behring Diagnostics Gmbh
Dade Behring Marburg Gmbh
Siemens Healthcare Diagnostics Products Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25915149&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2096888(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Herman Keuper, Walter Matzmorr, Wilfried Freudenberg, Behringwerke Aktiengesellschaft, Behring Diagnostics Gmbh, Dade Behring Marburg Gmbh, Siemens Healthcare Diagnostics Products Gmbh filed Critical Herman Keuper
Publication of CA2096888A1 publication Critical patent/CA2096888A1/en
Application granted granted Critical
Publication of CA2096888C publication Critical patent/CA2096888C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16661—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32661—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to a process for the inactivation of viruses in a solution of proteins by brief heating.
CA002096888A 1992-05-26 1993-05-25 Process for the inactivation of viruses in preparations of proteins Expired - Fee Related CA2096888C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEP4217355.8 1992-05-26
DE4217355 1992-05-26
DE4240103A DE4240103A1 (en) 1992-05-26 1992-11-28 Process for inactivating viruses in protein preparations
DEP4240103.8 1992-11-28

Publications (2)

Publication Number Publication Date
CA2096888A1 true CA2096888A1 (en) 1993-11-27
CA2096888C CA2096888C (en) 2004-04-27

Family

ID=25915149

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002096888A Expired - Fee Related CA2096888C (en) 1992-05-26 1993-05-25 Process for the inactivation of viruses in preparations of proteins

Country Status (8)

Country Link
EP (1) EP0571771B2 (en)
JP (1) JP3650410B2 (en)
KR (1) KR940005805A (en)
AT (1) ATE194648T1 (en)
AU (1) AU3876793A (en)
CA (1) CA2096888C (en)
DE (2) DE4240103A1 (en)
ES (1) ES2149791T5 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376209B2 (en) * 1997-05-17 2002-04-23 Dade Behring Marburg Gmbh Increasing the FVII sensitivity of a thromboplastin reagent
US10047596B2 (en) 2015-07-23 2018-08-14 General Electric Company System and method for disposal of water produced from a plurality of wells of a well-pad
US10077646B2 (en) 2015-07-23 2018-09-18 General Electric Company Closed loop hydrocarbon extraction system and a method for operating the same
US10323494B2 (en) 2015-07-23 2019-06-18 General Electric Company Hydrocarbon production system and an associated method thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1016029C2 (en) * 2000-08-28 2002-03-01 Gelatine Smits Beheer B V Method of eliminating disease causing agents by applying heating.
BR0115584A (en) * 2000-11-24 2003-09-23 Breath Ltd Sterilization of pharmaceuticals
JP6723563B2 (en) * 2015-04-20 2020-07-15 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー Virus inactivation
US11052165B2 (en) 2015-04-20 2021-07-06 Global Life Sciences Solutions Usa Llc Method for virus clearance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124506B1 (en) * 1983-05-02 1988-08-17 IMMUNO Aktiengesellschaft für chemisch-medizinische Produkte Method of inactivating pathogens
US4695454A (en) * 1985-04-01 1987-09-22 New York Blood Center, Inc. Process for preparing hepatitis B surface antigen containing particles in novel forms which are highly immunogenic
IE81149B1 (en) * 1987-02-12 2000-05-03 Genentech Inc Methods and deoxyribonucleic acid for the preparation of tissue factor protein
DE3905066A1 (en) * 1989-02-18 1990-08-23 Behringwerke Ag HEAT EXCHANGER MODULE
FR2664165B1 (en) * 1990-07-03 1992-10-16 Lille Transfusion Sanguine COMPOSITION FOR STABILIZING BLOOD PLASMA DURING PASTEURIZATION.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376209B2 (en) * 1997-05-17 2002-04-23 Dade Behring Marburg Gmbh Increasing the FVII sensitivity of a thromboplastin reagent
US10047596B2 (en) 2015-07-23 2018-08-14 General Electric Company System and method for disposal of water produced from a plurality of wells of a well-pad
US10077646B2 (en) 2015-07-23 2018-09-18 General Electric Company Closed loop hydrocarbon extraction system and a method for operating the same
US10323494B2 (en) 2015-07-23 2019-06-18 General Electric Company Hydrocarbon production system and an associated method thereof

Also Published As

Publication number Publication date
EP0571771A2 (en) 1993-12-01
CA2096888C (en) 2004-04-27
JPH0665091A (en) 1994-03-08
JP3650410B2 (en) 2005-05-18
EP0571771B2 (en) 2004-10-20
ES2149791T5 (en) 2005-05-16
EP0571771B1 (en) 2000-07-12
ATE194648T1 (en) 2000-07-15
KR940005805A (en) 1994-03-22
ES2149791T3 (en) 2000-11-16
EP0571771A3 (en) 1994-07-06
DE4240103A1 (en) 1993-12-02
AU3876793A (en) 1993-12-02
DE59310073D1 (en) 2000-08-17

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed