FI931474A - Peptider med modifikationer i n-terminalen - Google Patents

Peptider med modifikationer i n-terminalen Download PDF

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Publication number
FI931474A
FI931474A FI931474A FI931474A FI931474A FI 931474 A FI931474 A FI 931474A FI 931474 A FI931474 A FI 931474A FI 931474 A FI931474 A FI 931474A FI 931474 A FI931474 A FI 931474A
Authority
FI
Finland
Prior art keywords
radical
direct linkage
formula
cyclo
hetero
Prior art date
Application number
FI931474A
Other languages
English (en)
Finnish (fi)
Other versions
FI931474A0 (fi
Inventor
Gerhard Breipohl
Stephan Henke
Jochen Knolle
Bernward Schoelkens
Hans-Georg Alpermann
Hermann Gerhards
Klaus Wirth
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI931474A0 publication Critical patent/FI931474A0/fi
Publication of FI931474A publication Critical patent/FI931474A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mobile Radio Communication Systems (AREA)
  • Transceivers (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI931474A 1992-04-04 1993-04-01 Peptider med modifikationer i n-terminalen FI931474A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4211406 1992-04-04

Publications (2)

Publication Number Publication Date
FI931474A0 FI931474A0 (fi) 1993-04-01
FI931474A true FI931474A (fi) 1993-10-05

Family

ID=6456125

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931474A FI931474A (fi) 1992-04-04 1993-04-01 Peptider med modifikationer i n-terminalen

Country Status (25)

Country Link
US (1) US5597803A (el)
EP (1) EP0564972B1 (el)
JP (1) JP3426639B2 (el)
KR (1) KR100273825B1 (el)
CN (1) CN1040330C (el)
AT (1) ATE183197T1 (el)
AU (1) AU667707B2 (el)
BR (1) BR9301436A (el)
CA (1) CA2093305A1 (el)
CZ (1) CZ285698B6 (el)
DE (1) DE59309726D1 (el)
DK (1) DK0564972T3 (el)
ES (1) ES2136626T3 (el)
FI (1) FI931474A (el)
GR (1) GR3031543T3 (el)
HU (1) HU217613B (el)
IL (1) IL105287A (el)
MX (1) MX9301926A (el)
NO (1) NO311941B1 (el)
NZ (1) NZ247317A (el)
PL (1) PL175901B1 (el)
RU (1) RU2109747C1 (el)
SK (1) SK281970B6 (el)
TW (1) TW258739B (el)
ZA (1) ZA932399B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU696429B2 (en) * 1994-03-09 1998-09-10 Cortech, Inc. Bradykinin antagonist peptides incorporating n-substituted glycines
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
FR2790260B1 (fr) 1999-02-26 2001-05-04 Fournier Ind & Sante Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique
US6699486B1 (en) 1999-11-18 2004-03-02 Bolla Corporation Treatment or prevention of photoaging and skin cancer
US7105172B1 (en) 1999-11-18 2006-09-12 Bolla John D Treatment of rosacea
US20040248809A1 (en) * 2003-02-07 2004-12-09 Aventis Pharma Deutschland Gmbh Use of antagonists of the bradykinin B2 receptor for the treatment of osteoarthrosis
US20210238230A1 (en) 2018-04-20 2021-08-05 Fresenius Kabi Ipsum S.R.L. A method for production of high purity icatibant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210584A (en) * 1979-01-15 1980-07-01 Eli Lilly And Company Vindesine synthesis
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
EP0502987B1 (en) * 1989-12-08 1994-08-31 Trustees Of Boston University Acylated bradykinin antagonists and uses therefor
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina

Also Published As

Publication number Publication date
KR930021656A (ko) 1993-11-22
DK0564972T3 (da) 2000-01-24
EP0564972A2 (de) 1993-10-13
ATE183197T1 (de) 1999-08-15
NZ247317A (en) 1995-03-28
HU9300972D0 (en) 1993-06-28
HU217613B (hu) 2000-03-28
US5597803A (en) 1997-01-28
NO931287L (no) 1993-10-05
AU667707B2 (en) 1996-04-04
BR9301436A (pt) 1993-10-13
FI931474A0 (fi) 1993-04-01
NO311941B1 (no) 2002-02-18
IL105287A0 (en) 1993-08-18
MX9301926A (es) 1993-10-01
TW258739B (el) 1995-10-01
CA2093305A1 (en) 1993-10-05
DE59309726D1 (de) 1999-09-16
KR100273825B1 (ko) 2000-12-15
PL175901B1 (pl) 1999-03-31
ZA932399B (en) 1993-10-19
CN1040330C (zh) 1998-10-21
SK281970B6 (sk) 2001-09-11
IL105287A (en) 1999-12-31
CN1077202A (zh) 1993-10-13
EP0564972A3 (en) 1994-10-05
GR3031543T3 (en) 2000-01-31
JP3426639B2 (ja) 2003-07-14
JPH0665289A (ja) 1994-03-08
EP0564972B1 (de) 1999-08-11
CZ285698B6 (cs) 1999-10-13
HUT64775A (en) 1994-02-28
NO931287D0 (no) 1993-04-02
PL298362A1 (en) 1993-10-18
ES2136626T3 (es) 1999-12-01
CZ57293A3 (en) 1994-03-16
SK28993A3 (en) 1993-11-10
RU2109747C1 (ru) 1998-04-27
AU3565193A (en) 1993-10-07

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