FI925820A0 - Bisbenso- eller bensopyrodcykloheptapiperiden-, piperidyliden och pieratzinfoereningar och -kompositioner - Google Patents

Bisbenso- eller bensopyrodcykloheptapiperiden-, piperidyliden och pieratzinfoereningar och -kompositioner

Info

Publication number
FI925820A0
FI925820A0 FI925820A FI925820A FI925820A0 FI 925820 A0 FI925820 A0 FI 925820A0 FI 925820 A FI925820 A FI 925820A FI 925820 A FI925820 A FI 925820A FI 925820 A0 FI925820 A0 FI 925820A0
Authority
FI
Finland
Prior art keywords
och
pieratzinfoereningar
cospositioner
bisbenso
bensopyrodcykloheptapiperiden
Prior art date
Application number
FI925820A
Other languages
English (en)
Finnish (fi)
Other versions
FI925820L (fi
FI925820A7 (fi
Inventor
John J Piwinski
Michael J Green
Jesse Wong
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI925820L publication Critical patent/FI925820L/fi
Publication of FI925820A7 publication Critical patent/FI925820A7/fi
Publication of FI925820A0 publication Critical patent/FI925820A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
FI925820A 1990-06-22 1991-06-21 Bisbenso- eller bensopyrodcykloheptapiperiden-, piperidyliden och pieratzinfoereningar och -kompositioner FI925820A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54228090A 1990-06-22 1990-06-22
PCT/US1991/004162 WO1992000293A1 (en) 1990-06-22 1991-06-21 Bis-benzo or benzopyrido cyclo hepta piperidene, piperidylidene and piperazine compounds and compositions

Publications (3)

Publication Number Publication Date
FI925820L FI925820L (fi) 1992-12-22
FI925820A7 FI925820A7 (fi) 1992-12-22
FI925820A0 true FI925820A0 (fi) 1992-12-22

Family

ID=24163110

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925820A FI925820A0 (fi) 1990-06-22 1991-06-21 Bisbenso- eller bensopyrodcykloheptapiperiden-, piperidyliden och pieratzinfoereningar och -kompositioner

Country Status (26)

Country Link
US (1) US5422351A (cs)
EP (1) EP0535152B1 (cs)
JP (1) JPH0761998B2 (cs)
KR (1) KR960012368B1 (cs)
AT (1) ATE126226T1 (cs)
AU (1) AU646878B2 (cs)
CA (1) CA2085878C (cs)
CZ (1) CZ284610B6 (cs)
DE (2) DE122008000047I2 (cs)
DK (1) DK0535152T3 (cs)
ES (1) ES2096657T3 (cs)
FI (1) FI925820A0 (cs)
GR (1) GR3017924T3 (cs)
HK (1) HK186496A (cs)
HU (1) HU220622B1 (cs)
IE (1) IE68935B1 (cs)
IL (1) IL98572A (cs)
NL (1) NL300378I2 (cs)
NO (1) NO303223B1 (cs)
NZ (1) NZ238629A (cs)
OA (1) OA10032A (cs)
PL (1) PL173224B1 (cs)
RU (1) RU2086549C1 (cs)
SK (1) SK374892A3 (cs)
WO (1) WO1992000293A1 (cs)
ZA (1) ZA914764B (cs)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8854091A (en) * 1990-10-10 1992-05-20 Schering Corporation Bis-benzo cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use
AU2028892A (en) * 1991-05-23 1992-12-30 Schering Corporation Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use
CA2114009A1 (en) * 1991-07-23 1993-02-04 Jesse K. Wong Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use
JP2974529B2 (ja) * 1992-02-20 1999-11-10 北陸製薬株式会社 両性型三環系化合物
WO1993018744A1 (en) * 1992-03-23 1993-09-30 Janssen Pharmaceutica N.V. Agent for use as an anti-irritant
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
US5721236A (en) 1993-10-15 1998-02-24 Schering Corporation Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US6075025A (en) 1993-10-15 2000-06-13 Schering Corporation Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US5719148A (en) * 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5661152A (en) * 1993-10-15 1997-08-26 Schering Corporation Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US6365588B1 (en) 1993-10-15 2002-04-02 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
ES2087818B1 (es) * 1993-11-24 1997-03-16 Uriach & Cia Sa J 8-cloro-11-(1-((5-metil-3-piridil)metil)-4-piperidiliden)-6,11-dihidro-5h-benzo-(5,6)cicloheptal(1,2-b)piridina, fumarato.
ES2087026B1 (es) * 1994-07-28 1997-03-16 Uriach & Cia Sa J Nuevo derivado de la benzo(5,6)ciclohepta- (1.2-b) piridina.
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
US7214683B1 (en) 1994-12-30 2007-05-08 Sepracor Inc. Compositions of descarboethoxyloratadine
US7211582B1 (en) 1994-12-30 2007-05-01 Sepracor Inc. Methods for treating urticaria using descarboethoxyloratadine
US5684013A (en) * 1995-03-24 1997-11-04 Schering Corporation Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5700806A (en) * 1995-03-24 1997-12-23 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US5801175A (en) * 1995-04-07 1998-09-01 Schering Corporation Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US5891872A (en) * 1995-04-07 1999-04-06 Schering Corporation Tricyclic compounds
US5712280A (en) * 1995-04-07 1998-01-27 Schering Corporation Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
IL117798A (en) * 1995-04-07 2001-11-25 Schering Plough Corp Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
US5874442A (en) * 1995-12-22 1999-02-23 Schering-Plough Corporation Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
CA2265763A1 (en) * 1996-09-13 1998-03-19 Alan B. Cooper Tricyclic piperidinyl compounds useful as inhibitors of farnesyl-protein transferase
AU4337597A (en) * 1996-09-13 1998-04-02 Schering Corporation Substituted benzocycloheptapyridine useful as inhibitors of farnesyl-protein tr ansferase
US5965570A (en) * 1996-09-13 1999-10-12 Schering Corporation Tricyclic piperidinyl compounds useful as inhibitors of farnesyl-protein transferase
DK0934312T3 (da) * 1996-10-04 2003-07-21 Novo Nordisk As 1,4-disubstituerede piperaziner
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
UA62976C2 (en) * 1997-07-02 2004-01-15 Schering Corp Polymorphs of 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridine
US5958940A (en) * 1997-09-11 1999-09-28 Schering Corporation Tricyclic compounds useful as inhibitors of farnesyl-protein transferase
WO1999019322A1 (en) * 1997-10-10 1999-04-22 Schering Corporation ETHYL 4-(8-CHLORO-5, 6-DIHYDRO-11H- BENZO[5,6]CYCLOHEPTA [1,2-b]PYRIDIN -11-YLIDENE)-1- PIPERIDENE CARBOXYLATE POLYMORPH
US6100274A (en) * 1999-07-07 2000-08-08 Schering Corporation 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
US6114346A (en) 1999-10-22 2000-09-05 Schering Corporation Treating sleep disorders using desloratadine
SK287684B6 (sk) 1999-12-20 2011-06-06 Schering Corporation Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním
SK287105B6 (sk) 1999-12-20 2009-12-07 Schering Corporation Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions
AR033680A1 (es) * 2000-08-30 2004-01-07 Schering Corp Compuestos triciclicos utiles como inhibidores de la farnesil proteino transferasa y su uso para la manufactura de medicamentos como agentes antitumorales
KR20110117731A (ko) * 2003-05-30 2011-10-27 랜박시 래보러터리스 리미티드 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도
WO2006010202A1 (en) * 2004-07-28 2006-02-02 Ian Gray Pump control system
HRP20110804T1 (hr) 2005-06-23 2011-11-30 Merck Sharp & Dohme Corp. Benzocikloheptapiridini kao inhibitori receptora tirozin kinaze met
EP1948599A1 (en) * 2005-11-08 2008-07-30 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
CL2007000667A1 (es) * 2006-03-14 2008-03-14 Ranbaxi Lab Ltd Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
TW200813021A (en) 2006-07-10 2008-03-16 Merck & Co Inc Tyrosine kinase inhibitors
WO2008010087A2 (en) * 2006-07-14 2008-01-24 Ranbaxy Laboratories Limited Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof
US9296731B2 (en) * 2011-06-28 2016-03-29 Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. Anti-allergy benzocycloheptathiophene derivatives
CN103113348B (zh) * 2013-02-18 2015-03-25 扬子江药业集团江苏海慈生物药业有限公司 枸地氯雷他定的假多晶型及其制备方法
CN106588761B (zh) * 2016-11-22 2018-12-14 宜昌东阳光药业股份有限公司 一种氯雷他定中间体的合成方法
CN109608438A (zh) * 2018-12-05 2019-04-12 杭州澳医保灵药业有限公司 中间体化合物、其制备方法和应用、以及富马酸卢帕他定杂质j的制备方法
CN113004245B (zh) * 2019-12-20 2022-04-15 南京亿华药业有限公司 一种地氯雷他定制备方法
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途
CN113880808B (zh) * 2020-07-03 2024-12-31 合肥医工医药股份有限公司 一类三唑类化合物、制备方法及其医药用途
CN115433123B (zh) * 2022-10-08 2024-06-28 上海壮铭生物医药有限公司 一种氯雷他定中间体的制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA780443A (en) * 1968-03-12 Sandoz Patents Limited 10 h-(1) benzothiopyrano (3,2-b) pyridine derivatives
US3267094A (en) * 1962-09-12 1966-08-16 Colgate Palmolive Co Morphanthridine derivatives
GB1046543A (en) * 1963-02-22 1966-10-26 Sandoz Ag Improvements in or relating to azathiaxanthene derivatives
US3419565A (en) * 1963-04-24 1968-12-31 Schering Corp Aza-dibenzocycloheptenes
NL132137C (cs) * 1963-04-24
US3381000A (en) * 1963-10-16 1968-04-30 Colgate Palmolive Co Certain 11-basic substituted-5, 6-dihydromorphanthridine compounds
BE638971A (cs) * 1963-10-21
US3325501A (en) * 1964-02-18 1967-06-13 Sandoz Ltd 9-[piperidylidene(4')]-1-aza-thiaxanthene-10-oxides and derivatives
US3336303A (en) * 1965-08-11 1967-08-15 Searle & Co Dibenzo-azacycloalkane-n-carboxylic acid hydrazides
US3409621A (en) * 1966-04-01 1968-11-05 Schering Corp Piperazino-aza-dibenzo-[a, d]-cycloheptenes
US3391143A (en) * 1966-05-16 1968-07-02 Smith Kline French Lab 9-piperidyl and 9-piperidylidene derivatives of acridan
US3504088A (en) * 1966-12-05 1970-03-31 Ciba Geigy Corp Pharmaceutical composition containing 11-amino-6-morphanthridones
US3803154A (en) * 1969-08-07 1974-04-09 Colgate Palmolive Co 11-cyclicaminoalkylidenemorphanthridines
US3803153A (en) * 1970-11-16 1974-04-09 Schering Corp Benzopyrano pyridines
US3717647A (en) * 1971-04-09 1973-02-20 Schering Corp Alpha-nicotinoyl phenylacetonitriles
US4072756A (en) * 1973-05-17 1978-02-07 Sandoz Ltd. Tricyclo piperidino ketones and soporific compositions thereof
US4086350A (en) * 1974-11-06 1978-04-25 Smithkline Corporation Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms
US3966944A (en) * 1975-05-19 1976-06-29 Abbott Laboratories 10 (N-methyl-4-piperidylidene)-10H[1]-benzopyrano[3,2-b]-pyridine as an analgesic, anti-inflammatory and agent against type III hypersensitivity disease
US4021561A (en) * 1975-12-22 1977-05-03 Merck & Co., Inc. Trifluoromethylthio- and trifluoromethylsulfonyl-thioxanthen-9-ylidenepiperidines
DE2704934A1 (de) * 1976-02-17 1977-08-18 Sandoz Ag Organische verbindungen, ihre herstellung und verwendung
US4356184A (en) * 1980-06-04 1982-10-26 G. D. Searle & Co. Anti-allergic or antihypertensive 1-piperidinylmethyl benzenamines
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
US4355036A (en) * 1980-06-19 1982-10-19 Schering Corporation Tricyclic-substituted piperidine antihistamines
DE3170504D1 (en) * 1980-09-02 1985-06-20 Sandoz Ag Piperidylidene derivatives, their production and pharmaceutical compositions containing them
WO1985003707A1 (en) * 1984-02-15 1985-08-29 Schering Corporation 8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO AD5,6 BDCYCLOHEPTA AD1,2-b BDPYRIDINE AND ITS SALTS, PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
US4616023A (en) * 1984-04-05 1986-10-07 Merck & Co., Inc. Pharmaceutical compositions of 4-(dibenzo-[a,d]cycloalkenyl)piperazine compounds and methods
JPH0560831B1 (cs) * 1986-06-17 1993-09-03 Dainippon Pharmaceutical Co
US4826853A (en) * 1986-10-31 1989-05-02 Schering Corporation 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
JP2852659B2 (ja) * 1988-03-03 1999-02-03 富山化学工業株式会社 ピペラジン誘導体およびその塩
EP0411048A1 (en) * 1988-04-28 1991-02-06 Schering Corporation Novel benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use
CA2004211A1 (en) * 1988-11-30 1990-05-31 Masataka Syoji Piperidine derivatives and hyportensives containing the same

Also Published As

Publication number Publication date
HU9204079D0 (en) 1993-03-29
FI925820L (fi) 1992-12-22
HU220622B1 (hu) 2002-03-28
NL300378I1 (nl) 2009-05-06
NO303223B1 (no) 1998-06-15
IL98572A0 (en) 1992-07-15
CZ374892A3 (en) 1993-10-13
KR960012368B1 (ko) 1996-09-20
RU2086549C1 (ru) 1997-08-10
DE69112061T2 (de) 1995-12-14
OA10032A (en) 1996-10-14
NL300378I2 (nl) 2009-09-01
CA2085878A1 (en) 1991-12-23
ES2096657T3 (es) 1997-03-16
FI925820A7 (fi) 1992-12-22
NO924955D0 (no) 1992-12-21
AU646878B2 (en) 1994-03-10
CZ284610B6 (cs) 1999-01-13
SK280717B6 (sk) 2000-06-12
DK0535152T3 (da) 1995-09-25
IL98572A (en) 1995-07-31
CA2085878C (en) 2000-06-13
DE122008000047I2 (de) 2011-06-16
HK186496A (en) 1996-10-11
SK374892A3 (en) 2000-06-12
US5422351A (en) 1995-06-06
EP0535152A1 (en) 1993-04-07
PL297300A1 (cs) 1992-07-13
DE69112061D1 (de) 1995-09-14
PL173224B1 (pl) 1998-02-27
GR3017924T3 (en) 1996-01-31
JPH0761998B2 (ja) 1995-07-05
NO924955L (no) 1993-02-22
IE912124A1 (en) 1992-01-01
EP0535152B1 (en) 1995-08-09
JPH05507092A (ja) 1993-10-14
HUT63161A (en) 1993-07-28
IE68935B1 (en) 1996-07-24
ZA914764B (en) 1992-03-25
ATE126226T1 (de) 1995-08-15
WO1992000293A1 (en) 1992-01-09
AU8225291A (en) 1992-01-23
NZ238629A (en) 1993-09-27

Similar Documents

Publication Publication Date Title
FI925820A0 (fi) Bisbenso- eller bensopyrodcykloheptapiperiden-, piperidyliden och pieratzinfoereningar och -kompositioner
DE69115280D1 (de) Indolderivate, die die leukotrienbiosynthese hemmen.
FI925069A0 (fi) Nervskyddande indolon och naera anslutande derivat
NO853699L (no) Tetralinderivater, fremstilling og anvendelse derav.
PT937074E (pt) Benzonaftiridinas como terapeutica bronquica
ATE29255T1 (de) Succinimid-derivate und deren herstellung.
DK0623121T3 (da) Fremstilling af N-acetylneuraminsyrederivater
FI853624A0 (fi) 1-substituerade tetralinderivat, deras framstaellning och anvaendning.
ATE244222T1 (de) N-substituierte azabicycloheptan-derivate und ihre verwendung, z.b., als neuroleptika
IT1243801B (it) Intermedi per agenti chelanti con simmetria prefissata, e procedimentoper la loro preparazione
PT1003724E (pt) Derivados substituidos com accao antiviral
DK0775143T3 (da) 3-substituerede 3H-2,3-benzodiazepinderivater, deres fremstilling og anvendelse som lægdemidler
ES2118817T3 (es) 2-amino-5-mercaptotiadiazoles aminoalquil-substituidos, su obtencion y empleo.
ATE163402T1 (de) Substituierte ortho- ethenylphenylessigsäurederivate
DK0589903T3 (da) Aminoalkylsubstituerede 5-mercaptothiazoler, deres fremstilling og anvendelse
PT1104419E (pt) Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao
ES2125893T3 (es) 2-amino-1,3,4-tiadiazoles aminoalquilsubstituidos, su obtencion y su empleo.
FI102972B1 (fi) 20-metyyli-5,7-pregneadieeni-3b,21-diolijohdannaisia
NO974687L (no) Kondenserte <beta>-carboliner
MY115291A (en) New substituted pyrazole derivatives, processes for their preparation nad their use as herbicides