PT1003724E - Derivados substituidos com accao antiviral - Google Patents
Derivados substituidos com accao antiviralInfo
- Publication number
- PT1003724E PT1003724E PT97915425T PT97915425T PT1003724E PT 1003724 E PT1003724 E PT 1003724E PT 97915425 T PT97915425 T PT 97915425T PT 97915425 T PT97915425 T PT 97915425T PT 1003724 E PT1003724 E PT 1003724E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- substituted derivatives
- antiviral action
- date
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19613591A DE19613591A1 (de) | 1996-04-04 | 1996-04-04 | Substituierte-Chinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1003724E true PT1003724E (pt) | 2003-06-30 |
Family
ID=7790532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97915425T PT1003724E (pt) | 1996-04-04 | 1997-03-25 | Derivados substituidos com accao antiviral |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6114349A (pt) |
| EP (1) | EP1003724B1 (pt) |
| JP (1) | JP4231107B2 (pt) |
| AT (1) | ATE232519T1 (pt) |
| AU (1) | AU2291297A (pt) |
| DE (2) | DE19613591A1 (pt) |
| DK (1) | DK1003724T3 (pt) |
| ES (1) | ES2192675T3 (pt) |
| PT (1) | PT1003724E (pt) |
| WO (1) | WO1997037977A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
| GB9930061D0 (en) * | 1999-12-20 | 2000-02-09 | Glaxo Group Ltd | Quinolone compounds for use in treating viral infections |
| WO2002024650A2 (en) * | 2000-09-19 | 2002-03-28 | Centre National De La Recherche Scientifique (Cnrs) | Pyridinone and pyridinethione derivatives having hiv inhibiting properties |
| US7348433B2 (en) | 2001-12-14 | 2008-03-25 | Merck Frosst Canada & Co. | Quinolinones as prostaglandin receptor ligands |
| CA2537325A1 (en) * | 2003-09-19 | 2005-03-31 | Gilead Sciences, Inc. | Aza-quinolinol phosphonate integrase inhibitor compounds |
| AU2005249363A1 (en) * | 2004-04-14 | 2005-12-15 | Zhenhong R. Cai | Phosphonate analogs of HIV integrase inhibitor compounds |
| WO2007022946A1 (de) | 2005-08-21 | 2007-03-01 | Abbott Gmbh & Co. Kg | Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| TW200829554A (en) * | 2006-09-29 | 2008-07-16 | Tibotec Pharm Ltd | Quinolinone derivatives |
| CN113087664B (zh) * | 2021-03-22 | 2022-03-11 | 云南中烟工业有限责任公司 | 一种喹啉生物碱类化合物及其制备方法与应用 |
| US20240325374A1 (en) * | 2021-07-23 | 2024-10-03 | The Research Institute At Nationwide Children's Hospital | Inhibiting intracellular pathogens |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2164639T3 (es) * | 1991-04-15 | 2002-03-01 | Aventis Pharma Gmbh | Quinoxalinas, procedimiento para su preparacion y su empleo. |
| GB9125515D0 (en) * | 1991-11-29 | 1992-01-29 | Merck Sharp & Dohme | Therapeutic agents |
| TW304945B (pt) * | 1992-06-27 | 1997-05-11 | Hoechst Ag | |
| JPH0692939A (ja) * | 1992-09-16 | 1994-04-05 | Kyowa Hakko Kogyo Co Ltd | イミダゾール誘導体 |
-
1996
- 1996-04-04 DE DE19613591A patent/DE19613591A1/de not_active Withdrawn
-
1997
- 1997-03-25 PT PT97915425T patent/PT1003724E/pt unknown
- 1997-03-25 DK DK97915425T patent/DK1003724T3/da active
- 1997-03-25 WO PCT/EP1997/001496 patent/WO1997037977A1/de active IP Right Grant
- 1997-03-25 DE DE59709321T patent/DE59709321D1/de not_active Expired - Lifetime
- 1997-03-25 JP JP53578997A patent/JP4231107B2/ja not_active Expired - Fee Related
- 1997-03-25 ES ES97915425T patent/ES2192675T3/es not_active Expired - Lifetime
- 1997-03-25 AT AT97915425T patent/ATE232519T1/de not_active IP Right Cessation
- 1997-03-25 AU AU22912/97A patent/AU2291297A/en not_active Abandoned
- 1997-03-25 EP EP97915425A patent/EP1003724B1/de not_active Expired - Lifetime
- 1997-03-25 US US09/155,647 patent/US6114349A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE59709321D1 (de) | 2003-03-20 |
| DE19613591A1 (de) | 1997-10-09 |
| WO1997037977A1 (de) | 1997-10-16 |
| US6114349A (en) | 2000-09-05 |
| DK1003724T3 (da) | 2003-05-05 |
| ES2192675T3 (es) | 2003-10-16 |
| EP1003724A1 (de) | 2000-05-31 |
| JP2000508299A (ja) | 2000-07-04 |
| ATE232519T1 (de) | 2003-02-15 |
| AU2291297A (en) | 1997-10-29 |
| EP1003724B1 (de) | 2003-02-12 |
| JP4231107B2 (ja) | 2009-02-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY2509B1 (en) | New thiazole derivatives with phosphodiesterase-inhibitting effect | |
| DK1070056T3 (da) | Phthalazinon-PDE III/IV-inhibitorer | |
| DE59703471D1 (de) | Betain-geminitenside auf der basis von aminen | |
| HRP20080664A2 (en) | Substituted pyridine herbicides | |
| ATE248175T1 (de) | Epothilonderivate und ihre verwendung als antitumormittel | |
| ES2083595T3 (es) | Derivados de indol que inhiben la biosintesis de leucotrienos. | |
| NO971766D0 (no) | Anvendelsen av dioksomorfoliner for bekjempning av endoparasitter, nye dioksomorfoliner samt deres fremstilling | |
| DK0889886T3 (da) | Hidtil ukendte, i 6-stilling substituerede phenanthridiner | |
| PT941221E (pt) | Dihidrobenzofuranos substituidos como inibidores de fosfodiesterase (pde) | |
| ATE234300T1 (de) | Benzonaphthyridine als bronchialtherapeutika | |
| PT998460E (pt) | Novos derivados de tetrazole | |
| PT1003724E (pt) | Derivados substituidos com accao antiviral | |
| ES2165052T3 (es) | Procedimiento para la preparacion de derivados de pirimidina. | |
| MX9306995A (es) | Derivados de acido orto-etenilfenilacetico sustituidos. | |
| SE9402241L (sv) | Inhibitor | |
| ATE154601T1 (de) | 4-amino-2-(hetero)aryl-butanamide verwenbar als 5-ht1a-antagonisten |