FI920435A - N-(aryloxyalkyl) heteroaryl-8 -azabicyclo/3.2.1./oktaner, mellanprodukter och deras framstaellnings -foerfarande och deras anvaendning som laekemedel. - Google Patents

N-(aryloxyalkyl) heteroaryl-8 -azabicyclo/3.2.1./oktaner, mellanprodukter och deras framstaellnings -foerfarande och deras anvaendning som laekemedel. Download PDF

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Publication number
FI920435A
FI920435A FI920435A FI920435A FI920435A FI 920435 A FI920435 A FI 920435A FI 920435 A FI920435 A FI 920435A FI 920435 A FI920435 A FI 920435A FI 920435 A FI920435 A FI 920435A
Authority
FI
Finland
Prior art keywords
och deras
octaner
framstaellnings
mellanprodukter
aryloxyalkyl
Prior art date
Application number
FI920435A
Other languages
English (en)
Other versions
FI111367B (fi
FI920435A0 (fi
Inventor
Edward J Glamkowski
David M Fink
Barbara E Kurys
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI920435A0 publication Critical patent/FI920435A0/fi
Publication of FI920435A publication Critical patent/FI920435A/fi
Application granted granted Critical
Publication of FI111367B publication Critical patent/FI111367B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
FI920435A 1991-02-04 1992-01-31 Menetelmä terapeuttisesti käyttökelpoisten N-(aryylioksialkyyli)heteroaryyli-8-atsabisyklo[3.2.1]oktaanijohdannaisten valmistamiseksi ja menetelmässä käytetyt välituotteet FI111367B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65014491A 1991-02-04 1991-02-04
US65014491 1991-02-04

Publications (3)

Publication Number Publication Date
FI920435A0 FI920435A0 (fi) 1992-01-31
FI920435A true FI920435A (fi) 1992-08-05
FI111367B FI111367B (fi) 2003-07-15

Family

ID=24607667

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920435A FI111367B (fi) 1991-02-04 1992-01-31 Menetelmä terapeuttisesti käyttökelpoisten N-(aryylioksialkyyli)heteroaryyli-8-atsabisyklo[3.2.1]oktaanijohdannaisten valmistamiseksi ja menetelmässä käytetyt välituotteet

Country Status (21)

Country Link
EP (1) EP0498331B1 (fi)
JP (1) JPH089613B2 (fi)
KR (1) KR100222774B1 (fi)
AT (1) ATE138377T1 (fi)
AU (1) AU641842B2 (fi)
CA (1) CA2060573C (fi)
CZ (1) CZ284754B6 (fi)
DE (1) DE69210849T2 (fi)
DK (1) DK0498331T3 (fi)
ES (1) ES2089255T3 (fi)
FI (1) FI111367B (fi)
GR (1) GR3020094T3 (fi)
HU (2) HU217616B (fi)
IE (1) IE74905B1 (fi)
IL (1) IL100861A (fi)
MX (1) MX9200471A (fi)
NO (1) NO300040B1 (fi)
NZ (1) NZ241481A (fi)
PL (1) PL169092B1 (fi)
RU (1) RU2075479C1 (fi)
ZA (1) ZA92753B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9510459D0 (en) 1995-05-24 1995-07-19 Zeneca Ltd Bicyclic amines
TR199800628T2 (xx) * 1995-10-13 1998-07-21 Neurosearch A/S 8-Azabisiklo$3.2.1]okt-2-en t�revleri, bunlar�n haz�rlanmas� ve kullan�m�.
ES2218676T3 (es) * 1996-05-13 2004-11-16 Syngenta Limited Aminas biciclicas como insecticidas.
GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
GB9624611D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Bicyclic amine compounds
EP0944627B1 (en) 1996-11-26 2004-02-18 Syngenta Limited 8-azabicyclo 3.2.1]octane-, 8-azabicyclo 3.2.1]oct-6-ene-, 9-azabicyclo 3.3.1]nonane-, 9-aza-3-oxabicyclo 3.3.1]nonane- and 9-aza-3-thiabicyclo 3.3.1]nonane derivatives, their preparation and their use as insecticides
CZ298824B6 (cs) 1997-05-30 2008-02-20 Neurosearch A/S Deriváty 8-azabicyklo[3.2.1]okt-2-enu, zpusob jejich prípravy a jejich použití
US6251893B1 (en) * 1998-06-15 2001-06-26 Nps Allelix Corp. Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
AU1930901A (en) * 1999-12-20 2001-07-03 Eli Lilly And Company Azabicyclo(3.2.1)octane derivatives
AU2049501A (en) * 1999-12-20 2001-07-03 Eli Lilly And Company Benzofuran derivatives
WO2002066469A2 (en) * 2001-02-16 2002-08-29 Aventis Pharmaceuticals Inc. Novel heterocyclic amide derivatives and their use as dopamine d3 receptor ligands
US7247643B2 (en) * 2003-02-12 2007-07-24 Neurosearch A/S 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2548666A1 (fr) * 1983-07-08 1985-01-11 Delalande Sa Nouveaux derives du nor-tropane et du granatane, leur procede de preparation et leur application en therapeutique
DE3850742T2 (de) * 1987-11-04 1994-10-27 Beecham Group Plc Neue 4-Oxobenzotriazine und 4-Oxochinazoline.

Also Published As

Publication number Publication date
JPH0559049A (ja) 1993-03-09
IL100861A0 (en) 1992-11-15
NO920438L (no) 1992-08-05
EP0498331B1 (en) 1996-05-22
ZA92753B (en) 1992-10-28
AU1060592A (en) 1992-08-06
NO920438D0 (no) 1992-02-03
ATE138377T1 (de) 1996-06-15
HU207863B (en) 1993-06-28
IL100861A (en) 1997-02-18
HU217616B (hu) 2000-03-28
PL169092B1 (pl) 1996-05-31
DE69210849T2 (de) 1996-12-05
RU2075479C1 (ru) 1997-03-20
CA2060573C (en) 2002-08-13
FI111367B (fi) 2003-07-15
CZ284754B6 (cs) 1999-02-17
IE920349A1 (en) 1992-08-12
GR3020094T3 (en) 1996-08-31
DK0498331T3 (da) 1996-09-09
JPH089613B2 (ja) 1996-01-31
NO300040B1 (no) 1997-03-24
HUT62295A (en) 1993-04-28
NZ241481A (en) 1994-06-27
FI920435A0 (fi) 1992-01-31
CA2060573A1 (en) 1992-08-05
KR100222774B1 (ko) 1999-10-01
CS29792A3 (en) 1992-08-12
AU641842B2 (en) 1993-09-30
HU9200321D0 (en) 1992-04-28
IE74905B1 (en) 1997-08-13
DE69210849D1 (de) 1996-06-27
KR920016452A (ko) 1992-09-24
MX9200471A (es) 1992-08-01
PL293363A1 (en) 1993-03-08
HUT60494A (en) 1992-09-28
EP0498331A1 (en) 1992-08-12
HU9203977D0 (en) 1993-04-28
ES2089255T3 (es) 1996-10-01

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Owner name: HOECHST MARION ROUSSEL, INC.