NO920438D0 - N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, mellomprodukter og en fremgangsmaate for fremstilling deravsamt anvendelse som medikamenter - Google Patents

N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, mellomprodukter og en fremgangsmaate for fremstilling deravsamt anvendelse som medikamenter

Info

Publication number
NO920438D0
NO920438D0 NO920438A NO920438A NO920438D0 NO 920438 D0 NO920438 D0 NO 920438D0 NO 920438 A NO920438 A NO 920438A NO 920438 A NO920438 A NO 920438A NO 920438 D0 NO920438 D0 NO 920438D0
Authority
NO
Norway
Prior art keywords
loweralkoxy
chem
aryloxylkyl
octanes
azabicyclo
Prior art date
Application number
NO920438A
Other languages
English (en)
Other versions
NO920438L (no
NO300040B1 (no
Inventor
Edward J Glamowski
David M Fink
Barbara E Kurys
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO920438D0 publication Critical patent/NO920438D0/no
Publication of NO920438L publication Critical patent/NO920438L/no
Publication of NO300040B1 publication Critical patent/NO300040B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
NO920438A 1991-02-04 1992-02-03 N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, anvendelse av forbindelsene for fremstilling av et medikament og en farmasöytisk sammensetning NO300040B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65014491A 1991-02-04 1991-02-04

Publications (3)

Publication Number Publication Date
NO920438D0 true NO920438D0 (no) 1992-02-03
NO920438L NO920438L (no) 1992-08-05
NO300040B1 NO300040B1 (no) 1997-03-24

Family

ID=24607667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO920438A NO300040B1 (no) 1991-02-04 1992-02-03 N-(aryloksyalkyl)heteroaryl-8-azabicyklo(3.2.1.)oktaner, anvendelse av forbindelsene for fremstilling av et medikament og en farmasöytisk sammensetning

Country Status (21)

Country Link
EP (1) EP0498331B1 (no)
JP (1) JPH089613B2 (no)
KR (1) KR100222774B1 (no)
AT (1) ATE138377T1 (no)
AU (1) AU641842B2 (no)
CA (1) CA2060573C (no)
CZ (1) CZ284754B6 (no)
DE (1) DE69210849T2 (no)
DK (1) DK0498331T3 (no)
ES (1) ES2089255T3 (no)
FI (1) FI111367B (no)
GR (1) GR3020094T3 (no)
HU (2) HU217616B (no)
IE (1) IE74905B1 (no)
IL (1) IL100861A (no)
MX (1) MX9200471A (no)
NO (1) NO300040B1 (no)
NZ (1) NZ241481A (no)
PL (1) PL169092B1 (no)
RU (1) RU2075479C1 (no)
ZA (1) ZA92753B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9510459D0 (en) 1995-05-24 1995-07-19 Zeneca Ltd Bicyclic amines
US6100275A (en) * 1995-10-13 2000-08-08 Neurosearch A/S 8-azabicyclo[3.2.1.]oct-2-ene derivatives, their preparation and use
AU722015B2 (en) * 1996-05-13 2000-07-20 Zeneca Limited Bicyclic amines
GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
GB9624611D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Bicyclic amine compounds
HUP0000582A3 (en) 1996-11-26 2001-10-29 Zeneca Ltd Insecticidal, acaricidal and nematocidal 8-azabicyclo[3.2.1]octane-, 8-azabicyclo[3.2.1]oct-6-ene-, 9-azabicyclo[3.3.1]nonane-, 9-aza-3-oxabicyclo[3.3.1]nonane- and 9-aza-3-thiabicyclo[3.3.1]nonane derivatives, preparation and use thereof
CA2289574C (en) 1997-05-30 2007-04-24 Neurosearch A/S 8-azabicyclo(3,2,1)oct-2-ene and octane derivatives as cholinergic ligands at nicotinic ach receptors
US6251893B1 (en) * 1998-06-15 2001-06-26 Nps Allelix Corp. Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
US6835733B2 (en) 1999-12-20 2004-12-28 Eli Lilly And Company Tropane linked benzofuran derivatives
WO2001046187A1 (en) * 1999-12-20 2001-06-28 Eli Lilly And Company Azabicyclo[3.2.1]octane derivatives
JP4497815B2 (ja) * 2001-02-16 2010-07-07 アベンティス・ファーマスーティカルズ・インコーポレイテツド 新規な複素環式アミド誘導体およびドーパミンｄ３受容体リガンドとしてのその使用
AU2004212166B2 (en) * 2003-02-12 2010-07-29 Neurosearch A/S 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2548666A1 (fr) * 1983-07-08 1985-01-11 Delalande Sa Nouveaux derives du nor-tropane et du granatane, leur procede de preparation et leur application en therapeutique
DE3850742T2 (de) * 1987-11-04 1994-10-27 Beecham Group Plc Neue 4-Oxobenzotriazine und 4-Oxochinazoline.

Also Published As

Publication number Publication date
AU1060592A (en) 1992-08-06
MX9200471A (es) 1992-08-01
KR100222774B1 (ko) 1999-10-01
DK0498331T3 (da) 1996-09-09
HU217616B (hu) 2000-03-28
CA2060573A1 (en) 1992-08-05
RU2075479C1 (ru) 1997-03-20
HU9203977D0 (en) 1993-04-28
IL100861A0 (en) 1992-11-15
IL100861A (en) 1997-02-18
IE920349A1 (en) 1992-08-12
KR920016452A (ko) 1992-09-24
DE69210849D1 (de) 1996-06-27
DE69210849T2 (de) 1996-12-05
PL169092B1 (pl) 1996-05-31
NO920438L (no) 1992-08-05
FI920435A0 (fi) 1992-01-31
IE74905B1 (en) 1997-08-13
ZA92753B (en) 1992-10-28
EP0498331A1 (en) 1992-08-12
NZ241481A (en) 1994-06-27
HUT62295A (en) 1993-04-28
JPH0559049A (ja) 1993-03-09
CS29792A3 (en) 1992-08-12
PL293363A1 (en) 1993-03-08
CA2060573C (en) 2002-08-13
CZ284754B6 (cs) 1999-02-17
GR3020094T3 (en) 1996-08-31
JPH089613B2 (ja) 1996-01-31
HUT60494A (en) 1992-09-28
FI111367B (fi) 2003-07-15
ES2089255T3 (es) 1996-10-01
ATE138377T1 (de) 1996-06-15
FI920435A (fi) 1992-08-05
NO300040B1 (no) 1997-03-24
AU641842B2 (en) 1993-09-30
HU9200321D0 (en) 1992-04-28
HU207863B (en) 1993-06-28
EP0498331B1 (en) 1996-05-22

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