FI893364A0 - Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin. - Google Patents

Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin.

Info

Publication number
FI893364A0
FI893364A0 FI893364A FI893364A FI893364A0 FI 893364 A0 FI893364 A0 FI 893364A0 FI 893364 A FI893364 A FI 893364A FI 893364 A FI893364 A FI 893364A FI 893364 A0 FI893364 A0 FI 893364A0
Authority
FI
Finland
Prior art keywords
arabinofuranosyl
anhydro
framstaellning
thyme
procedure
Prior art date
Application number
FI893364A
Other languages
English (en)
Other versions
FI893364A (fi
Inventor
Charles William Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI893364A0 publication Critical patent/FI893364A0/fi
Publication of FI893364A publication Critical patent/FI893364A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/09—Pyrimidine radicals with arabinosyl as the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI893364A 1988-07-12 1989-07-11 Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin. FI893364A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/217,906 US5008384A (en) 1988-07-12 1988-07-12 Process for the production of O.sup. 2,2'-anhydro-1-(β-D-arabinofuranosyl)thymine

Publications (2)

Publication Number Publication Date
FI893364A0 true FI893364A0 (fi) 1989-07-11
FI893364A FI893364A (fi) 1990-01-13

Family

ID=22812966

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893364A FI893364A (fi) 1988-07-12 1989-07-11 Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin.

Country Status (21)

Country Link
US (1) US5008384A (fi)
EP (1) EP0351126B1 (fi)
JP (1) JPH075626B2 (fi)
KR (1) KR910008112B1 (fi)
CN (1) CN1039423A (fi)
AT (1) ATE117314T1 (fi)
AU (1) AU603042B2 (fi)
CA (1) CA1315776C (fi)
DD (2) DD284024A5 (fi)
DE (1) DE68920648T2 (fi)
DK (1) DK342189A (fi)
ES (1) ES2066853T3 (fi)
FI (1) FI893364A (fi)
GR (1) GR3015293T3 (fi)
HU (1) HUT50843A (fi)
IE (1) IE65735B1 (fi)
IL (1) IL90884A0 (fi)
NO (1) NO892821L (fi)
PT (1) PT91113B (fi)
YU (1) YU138789A (fi)
ZA (1) ZA895259B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3065350B2 (ja) * 1990-11-30 2000-07-17 ヤマサ醤油株式会社 １―（２，３―ジデオキシ―β―Ｄ―グリセロ―ペント―２―エノフラノシル）チミンの製造法
DE69415506T2 (de) * 1994-05-20 1999-08-12 Council Of Scientific And Industrial Research, New Delhi Verfahren zur Herstellung von Beta-Thymidine
US7125983B2 (en) 2000-11-29 2006-10-24 Mitsui Chemicals, Inc. L-nucleic acid derivatives and process for the synthesis thereof
BR0208517A (pt) * 2001-03-30 2005-02-01 Triangle Pharmaceuticals Inc Processo para a preparação de nucleosìdeos de 2'-halo-sg(b) l-arabinofuranosila
DE10216426A1 (de) * 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Verfahren zur Herstellung von beta-L-2'Deoxy-Thymidin
WO2004096149A2 (en) 2003-04-28 2004-11-11 Idenix (Cayman) Limited Industrially scalable nucleoside synthesis
EP1639121A4 (en) 2003-06-30 2008-04-16 Idenix Cayman Ltd SYNTHESIS OF BETA-L-2-DESOXYNUCLEOSIDES
CA2643748A1 (en) 2006-03-15 2007-09-20 Novartis Ag Process for preparing l-nucleic acid derivatives and intermediates thereof
EP2265274B1 (en) 2008-03-03 2018-11-21 Tosk, Inc. Methotrexate adjuvants to reduce toxicity and methods for using the same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322747A (en) * 1965-04-01 1967-05-30 Merck & Co Inc Thionocarbonate nucleosides
US3463850A (en) * 1967-01-03 1969-08-26 Merck & Co Inc Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof
US3658788A (en) * 1969-06-06 1972-04-25 Salk Inst For Biological Studi Aminooxazolines and products thereof and processes for synthesizing same
US3792040A (en) * 1970-03-19 1974-02-12 Syntex Corp Acyl derivatives of o2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosines and methods of preparing
US3812098A (en) * 1970-03-19 1974-05-21 Syntex Inc O2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosine derivatives and methods of making and related procedures
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
US3920630A (en) * 1970-09-24 1975-11-18 Upjohn Co 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation
SE391183B (sv) * 1971-04-15 1977-02-07 Asahi Chemical Ind 2',3'-0-sulfinylcytidin och syraadditionssalter derav till anvendning som mellanprodukt for framstellning av 2,2'-anhydro-(1-beta-d-arabinofuranosyl) cytosin
US3978042A (en) * 1975-01-31 1976-08-31 The Upjohn Company Process for preparing cyclocytidine derivatives
US4140850A (en) * 1977-08-29 1979-02-20 The Upjohn Company 2,2'-Anhydrotriazine nucleosides and process for preparing the same
JPS5649398A (en) * 1979-09-28 1981-05-02 Yamasa Shoyu Co Ltd Preparation of 1-beta-d-arabinofuranosyl-2,2'-cyclothymine
JPS636557A (ja) * 1986-06-26 1988-01-12 Sharp Corp 微細パタ−ン形成方法

Also Published As

Publication number Publication date
PT91113A (pt) 1990-02-08
ATE117314T1 (de) 1995-02-15
DD284024A5 (de) 1990-10-31
KR910008112B1 (ko) 1991-10-10
DK342189D0 (da) 1989-07-11
HUT50843A (en) 1990-03-28
IE892233L (en) 1990-01-12
EP0351126B1 (en) 1995-01-18
NO892821D0 (no) 1989-07-07
DD292003A5 (de) 1991-07-18
US5008384A (en) 1991-04-16
EP0351126A2 (en) 1990-01-17
PT91113B (pt) 1995-01-31
DK342189A (da) 1990-01-15
CA1315776C (en) 1993-04-06
GR3015293T3 (en) 1995-06-30
IE65735B1 (en) 1995-11-15
AU603042B2 (en) 1990-11-01
DE68920648D1 (de) 1995-03-02
YU138789A (en) 1990-12-31
AU3802089A (en) 1990-04-26
ZA895259B (en) 1991-02-27
KR900001704A (ko) 1990-02-27
ES2066853T3 (es) 1995-03-16
IL90884A0 (en) 1990-02-09
JPH075626B2 (ja) 1995-01-25
FI893364A (fi) 1990-01-13
EP0351126A3 (en) 1990-10-24
DE68920648T2 (de) 1995-05-18
NO892821L (no) 1990-01-15
CN1039423A (zh) 1990-02-07
JPH0259598A (ja) 1990-02-28

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: PFIZER INC.