FI881892A - Förfarande för framställning av nya, terapeutiskt användbara 1,2,5,6-tetrahydropyridinderivat - Google Patents

Förfarande för framställning av nya, terapeutiskt användbara 1,2,5,6-tetrahydropyridinderivat Download PDF

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Publication number
FI881892A
FI881892A FI881892A FI881892A FI881892A FI 881892 A FI881892 A FI 881892A FI 881892 A FI881892 A FI 881892A FI 881892 A FI881892 A FI 881892A FI 881892 A FI881892 A FI 881892A
Authority
FI
Finland
Prior art keywords
denotes
preparation
therapeutically useful
tetrahydropyridine derivatives
alkyl
Prior art date
Application number
FI881892A
Other languages
English (en)
Finnish (fi)
Other versions
FI93211B (sv
FI93211C (sv
FI881892A0 (sv
Inventor
Giulio Galliani
Fernando Barzaghi
Carla Bonetti
Emilio Toja
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI881892A0 publication Critical patent/FI881892A0/sv
Publication of FI881892A publication Critical patent/FI881892A/sv
Publication of FI93211B publication Critical patent/FI93211B/sv
Application granted granted Critical
Publication of FI93211C publication Critical patent/FI93211C/sv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI881892A 1987-04-24 1988-04-22 Förfarande för framställning av nya, terapeutiskt användbara 1,2,5,6-tetrahydropyridinderivat FI93211C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2026087 1987-04-24
IT20260/87A IT1203971B (it) 1987-04-24 1987-04-24 Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Publications (4)

Publication Number Publication Date
FI881892A0 FI881892A0 (sv) 1988-04-22
FI881892A true FI881892A (sv) 1988-10-25
FI93211B FI93211B (sv) 1994-11-30
FI93211C FI93211C (sv) 1995-03-10

Family

ID=11165225

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881892A FI93211C (sv) 1987-04-24 1988-04-22 Förfarande för framställning av nya, terapeutiskt användbara 1,2,5,6-tetrahydropyridinderivat

Country Status (22)

Country Link
EP (1) EP0288394B1 (sv)
JP (1) JP2727192B2 (sv)
KR (1) KR960012365B1 (sv)
AT (1) ATE80387T1 (sv)
AU (1) AU614283B2 (sv)
CA (1) CA1340986C (sv)
DE (1) DE3874396T2 (sv)
DK (1) DK167758B1 (sv)
ES (1) ES2043863T3 (sv)
FI (1) FI93211C (sv)
GR (1) GR3005647T3 (sv)
HU (1) HU199795B (sv)
IE (1) IE63172B1 (sv)
IL (1) IL86157A (sv)
IT (1) IT1203971B (sv)
MX (1) MX11201A (sv)
NZ (1) NZ224357A (sv)
OA (1) OA08835A (sv)
PH (1) PH25574A (sv)
PT (1) PT87290B (sv)
SU (1) SU1678203A3 (sv)
ZA (1) ZA882595B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
DK177889A (da) * 1988-04-15 1989-10-16 Beecham Group Plc Hidtil ukendte forbindelser
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
ES2219636T3 (es) * 1989-04-13 2004-12-01 Beecham Group P.L.C. Nuevos compuestos.
AU8436291A (en) * 1990-08-24 1992-03-17 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
US5356914A (en) * 1990-10-12 1994-10-18 Beecham Group P.L.C. 1,2,5,6-tetrahydropyridine oxime derivatives
EP0537993A1 (en) * 1991-10-17 1993-04-21 Eli Lilly And Company Nicotinic activity of a series of arecolones and isoarecolones
AU3142793A (en) * 1991-12-18 1993-07-19 Warner-Lambert Company Transdermal delivery of (E)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-O- methyloxine HCL and related compounds in the treatment of cognitive disorders and for analgesia
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5362860A (en) * 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
US6250886B1 (en) 1999-09-03 2001-06-26 Chittom International, Inc. Axial flow fan and fan blade

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
JPH0641332B2 (ja) * 1986-09-17 1994-06-01 株式会社共同精機工作所 断裁機へのシ−ト類供給装置
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment

Also Published As

Publication number Publication date
HUT47248A (en) 1989-02-28
NZ224357A (en) 1992-01-29
IE881207L (en) 1988-10-24
EP0288394A2 (fr) 1988-10-26
FI93211B (sv) 1994-11-30
EP0288394B1 (fr) 1992-09-09
DK216388A (da) 1988-10-25
DK216388D0 (da) 1988-04-21
PT87290B (pt) 1992-08-31
PH25574A (en) 1991-08-08
PT87290A (pt) 1988-05-01
DE3874396D1 (de) 1992-10-15
KR960012365B1 (ko) 1996-09-20
IE63172B1 (en) 1995-03-22
IT1203971B (it) 1989-02-23
FI93211C (sv) 1995-03-10
ATE80387T1 (de) 1992-09-15
ZA882595B (en) 1989-07-26
SU1678203A3 (ru) 1991-09-15
HU199795B (en) 1990-03-28
AU1511188A (en) 1988-10-27
FI881892A0 (sv) 1988-04-22
EP0288394A3 (en) 1989-01-25
GR3005647T3 (sv) 1993-06-07
AU614283B2 (en) 1991-08-29
CA1340986C (fr) 2000-05-09
KR890016009A (ko) 1989-11-27
IL86157A (en) 1994-04-12
DK167758B1 (da) 1993-12-13
IL86157A0 (en) 1988-11-15
MX11201A (es) 1993-10-01
IT8720260A0 (it) 1987-04-24
OA08835A (fr) 1989-03-31
DE3874396T2 (de) 1993-04-22
JPS63284160A (ja) 1988-11-21
JP2727192B2 (ja) 1998-03-11
ES2043863T3 (es) 1994-01-01

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: HOECHST MARION ROUSSEL

FG Patent granted

Owner name: AVENTIS PHARMA S.A.

MA Patent expired