IT1222526B - Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali - Google Patents
Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinaliInfo
- Publication number
- IT1222526B IT1222526B IT8721687A IT2168787A IT1222526B IT 1222526 B IT1222526 B IT 1222526B IT 8721687 A IT8721687 A IT 8721687A IT 2168787 A IT2168787 A IT 2168787A IT 1222526 B IT1222526 B IT 1222526B
- Authority
- IT
- Italy
- Prior art keywords
- carbon atoms
- tetraidropiridin
- oxyme
- carboxaldehyde
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8721687A IT1222526B (it) | 1987-08-21 | 1987-08-21 | Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
NO883521A NO174504B (no) | 1987-08-21 | 1988-08-08 | Analogifremgangsmaate for fremstilling av terapeutisk virksomme derivater av 1,2,5,6-tetrahydropyridin-3-carboxaldehyd-oxim |
IL8887430A IL87430A0 (en) | 1987-08-21 | 1988-08-12 | Novel derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde,the process for their preparation,their use as medicaments and the compositions containing them |
DK457388A DK457388A (da) | 1987-08-21 | 1988-08-16 | Oximet af 1,2,5,6-tetrahydropyridin-3-carboxaldehyd, dets fremstilling samt laegemidler med indhold deraf |
MX1270788A MX12707A (es) | 1987-08-21 | 1988-08-17 | Procedimiento para la preparacion de nuevos derivados de la oxima del 1, 2, 5, 6-tetrahidropiridin-3-carboxaldehido. |
JP63203962A JPH07107048B2 (ja) | 1987-08-21 | 1988-08-18 | 新規の1,2,5,6−テトラヒドロピリジン−3−カルボキサアルデヒドロのオキシムの誘導体、それらの製造方法、それらの薬剤としての使用及びそれらを含有する組成物 |
ZA886131A ZA886131B (en) | 1987-08-21 | 1988-08-18 | Derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde,the process for their preparation,their use as medicaments and the compositions containing them |
CA000575166A CA1340987C (fr) | 1987-08-21 | 1988-08-19 | Derives de l'oxime du 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
AT88402128T ATE71938T1 (de) | 1987-08-21 | 1988-08-19 | 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen. |
AU21100/88A AU608643B2 (en) | 1987-08-21 | 1988-08-19 | Novel derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them |
PT88302A PT88302B (pt) | 1987-08-21 | 1988-08-19 | Processo para a preparacao de novos derivados da oxima de 1,2,5,6-tetraidropidin-3-carboxaldeido |
SU4356622A SU1681723A3 (ru) | 1987-08-21 | 1988-08-19 | Способ получени производных оксимов 1,2,5,6-тетрагидропиридин-3-карбоксальдегида |
EP88402128A EP0308283B1 (fr) | 1987-08-21 | 1988-08-19 | Dérivés de l'oxime du 1,2,5,6-tétrahydropyridin-3-carboxaldéhyde, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant |
DE8888402128T DE3867986D1 (de) | 1987-08-21 | 1988-08-19 | 1,2,5,6-tetrahydropyridin-3-carboxaldehydoxim-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen. |
HU884414A HU201012B (en) | 1987-08-21 | 1988-08-19 | Process for producing 1,2,5,6-tetrahydropyridine-3-carboxaldehydeoxime derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
IE253888A IE61537B1 (en) | 1987-08-21 | 1988-08-19 | Novel derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them |
FI883869A FI90070C (fi) | 1987-08-21 | 1988-08-19 | Foerfarande foer framstaellning av terapeutiskt aktiva derivat av 1,2,5,6-tetrahydropyridin-3-karboxaldehydoxim |
ES198888402128T ES2038776T3 (es) | 1987-08-21 | 1988-08-19 | Procedimiento de preparacion de derivados de la oxima del 1,2,5,6-tetrahidropiridin-3-carboxaldehido. |
KR1019880010676A KR960014998B1 (ko) | 1987-08-21 | 1988-08-22 | 1,2,5,6-테트라히드로피리딘-3-카르복스알데히드의 옥심유도체, 이들의 제조방법, 약제로서의 이들의 용도 및 이들을 함유하는 조성물 |
NZ225902A NZ225902A (en) | 1987-08-21 | 1988-08-22 | Derivatives of 1,2,5,6 tetrahydropyridine-3-carboxaldehyde oxime and medicaments |
US07/234,632 US4921868A (en) | 1987-08-21 | 1988-08-22 | Carbamate derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, their use as medicaments and compositions containing them |
US07/863,466 US5231107A (en) | 1987-08-21 | 1992-04-01 | Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them |
GR910402203T GR3004249T3 (it) | 1987-08-21 | 1992-04-02 | |
HU95P/P00578P HU211913A9 (en) | 1987-08-21 | 1995-06-29 | 1,2,5,6-tetrahydropyridine-3-carboxaldehyde oxime derivatives, process for their preparation, their use as pharmaceutical compounds and compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8721687A IT1222526B (it) | 1987-08-21 | 1987-08-21 | Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8721687A0 IT8721687A0 (it) | 1987-08-21 |
IT1222526B true IT1222526B (it) | 1990-09-05 |
Family
ID=11185397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8721687A IT1222526B (it) | 1987-08-21 | 1987-08-21 | Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
Country Status (22)
Country | Link |
---|---|
US (1) | US4921868A (it) |
EP (1) | EP0308283B1 (it) |
JP (1) | JPH07107048B2 (it) |
KR (1) | KR960014998B1 (it) |
AT (1) | ATE71938T1 (it) |
AU (1) | AU608643B2 (it) |
CA (1) | CA1340987C (it) |
DE (1) | DE3867986D1 (it) |
DK (1) | DK457388A (it) |
ES (1) | ES2038776T3 (it) |
FI (1) | FI90070C (it) |
GR (1) | GR3004249T3 (it) |
HU (2) | HU201012B (it) |
IE (1) | IE61537B1 (it) |
IL (1) | IL87430A0 (it) |
IT (1) | IT1222526B (it) |
MX (1) | MX12707A (it) |
NO (1) | NO174504B (it) |
NZ (1) | NZ225902A (it) |
PT (1) | PT88302B (it) |
SU (1) | SU1681723A3 (it) |
ZA (1) | ZA886131B (it) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5231107A (en) * | 1987-08-21 | 1993-07-27 | Roussel Uclaf | Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them |
EP0338723B1 (en) * | 1988-04-15 | 1993-08-04 | Beecham Group Plc | Novel compounds |
US5278170A (en) * | 1989-04-13 | 1994-01-11 | Beecham Group P.L.C. | Azabicylo oxime compounds |
SG48315A1 (en) * | 1989-04-13 | 1998-04-17 | Beecham Group Plc | Novel compounds |
IT1240603B (it) * | 1990-03-14 | 1993-12-17 | Roussel Maestretti Spa | Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale |
IT1241138B (it) * | 1990-05-15 | 1993-12-29 | Roussel Pharma | Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
JPH06500550A (ja) * | 1990-08-24 | 1994-01-20 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | アザ二環式化合物、その製造方法および製造用中間体ならびにその化合物含有の医薬組成物 |
GB9019095D0 (en) * | 1990-09-01 | 1990-10-17 | Beecham Group Plc | Novel compounds |
US5356914A (en) * | 1990-10-12 | 1994-10-18 | Beecham Group P.L.C. | 1,2,5,6-tetrahydropyridine oxime derivatives |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1258847A (fr) * | 1960-02-12 | 1961-04-21 | Ciba Geigy | Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine |
IL81610A (en) * | 1986-02-27 | 1990-12-23 | Roussel Uclaf | Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them |
US4786648A (en) * | 1986-12-08 | 1988-11-22 | Warner-Lambert Company | O-substituted tetrahydropyridine oxime cholinergic agents |
IT1203971B (it) * | 1987-04-24 | 1989-02-23 | Roussel Maestretti Spa | Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti |
-
1987
- 1987-08-21 IT IT8721687A patent/IT1222526B/it active
-
1988
- 1988-08-08 NO NO883521A patent/NO174504B/no unknown
- 1988-08-12 IL IL8887430A patent/IL87430A0/xx not_active IP Right Cessation
- 1988-08-16 DK DK457388A patent/DK457388A/da not_active Application Discontinuation
- 1988-08-17 MX MX1270788A patent/MX12707A/es unknown
- 1988-08-18 JP JP63203962A patent/JPH07107048B2/ja not_active Expired - Fee Related
- 1988-08-18 ZA ZA886131A patent/ZA886131B/xx unknown
- 1988-08-19 HU HU884414A patent/HU201012B/hu not_active IP Right Cessation
- 1988-08-19 IE IE253888A patent/IE61537B1/en not_active IP Right Cessation
- 1988-08-19 SU SU4356622A patent/SU1681723A3/ru active
- 1988-08-19 DE DE8888402128T patent/DE3867986D1/de not_active Expired - Fee Related
- 1988-08-19 ES ES198888402128T patent/ES2038776T3/es not_active Expired - Lifetime
- 1988-08-19 FI FI883869A patent/FI90070C/fi not_active IP Right Cessation
- 1988-08-19 EP EP88402128A patent/EP0308283B1/fr not_active Expired - Lifetime
- 1988-08-19 AT AT88402128T patent/ATE71938T1/de not_active IP Right Cessation
- 1988-08-19 PT PT88302A patent/PT88302B/pt not_active IP Right Cessation
- 1988-08-19 CA CA000575166A patent/CA1340987C/fr not_active Expired - Fee Related
- 1988-08-19 AU AU21100/88A patent/AU608643B2/en not_active Ceased
- 1988-08-22 KR KR1019880010676A patent/KR960014998B1/ko not_active IP Right Cessation
- 1988-08-22 NZ NZ225902A patent/NZ225902A/xx unknown
- 1988-08-22 US US07/234,632 patent/US4921868A/en not_active Expired - Fee Related
-
1992
- 1992-04-02 GR GR910402203T patent/GR3004249T3/el unknown
-
1995
- 1995-06-29 HU HU95P/P00578P patent/HU211913A9/hu unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960717 |