PT88302A - Processo para a preparacao de novos derivados da oxima de 1,2,5,6-tetraidropidin-3-carboxaldeido - Google Patents

Processo para a preparacao de novos derivados da oxima de 1,2,5,6-tetraidropidin-3-carboxaldeido

Info

Publication number
PT88302A
PT88302A PT88302A PT8830288A PT88302A PT 88302 A PT88302 A PT 88302A PT 88302 A PT88302 A PT 88302A PT 8830288 A PT8830288 A PT 8830288A PT 88302 A PT88302 A PT 88302A
Authority
PT
Portugal
Prior art keywords
carbon atoms
tetraidropidin
carboxaldeido
oxima
possibly substituted
Prior art date
Application number
PT88302A
Other languages
English (en)
Other versions
PT88302B (pt
Inventor
Emilio Toja
Fernando Barzaghi
Giulio Galliani
Carla Bonetti
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT88302A publication Critical patent/PT88302A/pt
Publication of PT88302B publication Critical patent/PT88302B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT88302A 1987-08-21 1988-08-19 Processo para a preparacao de novos derivados da oxima de 1,2,5,6-tetraidropidin-3-carboxaldeido PT88302B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8721687A IT1222526B (it) 1987-08-21 1987-08-21 Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali

Publications (2)

Publication Number Publication Date
PT88302A true PT88302A (pt) 1989-09-14
PT88302B PT88302B (pt) 1995-03-31

Family

ID=11185397

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88302A PT88302B (pt) 1987-08-21 1988-08-19 Processo para a preparacao de novos derivados da oxima de 1,2,5,6-tetraidropidin-3-carboxaldeido

Country Status (22)

Country Link
US (1) US4921868A (pt)
EP (1) EP0308283B1 (pt)
JP (1) JPH07107048B2 (pt)
KR (1) KR960014998B1 (pt)
AT (1) ATE71938T1 (pt)
AU (1) AU608643B2 (pt)
CA (1) CA1340987C (pt)
DE (1) DE3867986D1 (pt)
DK (1) DK457388A (pt)
ES (1) ES2038776T3 (pt)
FI (1) FI90070C (pt)
GR (1) GR3004249T3 (pt)
HU (2) HU201012B (pt)
IE (1) IE61537B1 (pt)
IL (1) IL87430A0 (pt)
IT (1) IT1222526B (pt)
MX (1) MX12707A (pt)
NO (1) NO174504B (pt)
NZ (1) NZ225902A (pt)
PT (1) PT88302B (pt)
SU (1) SU1681723A3 (pt)
ZA (1) ZA886131B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231107A (en) * 1987-08-21 1993-07-27 Roussel Uclaf Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them
AU3301689A (en) * 1988-04-15 1989-10-26 Beecham Group Plc 1-azabicyclo-alkyl derivatives
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
ATE269330T1 (de) * 1989-04-13 2004-07-15 Beecham Group Plc Chemische verbindungen
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
EP0544773B1 (en) * 1990-08-24 1998-03-18 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
WO1992006959A1 (en) * 1990-10-12 1992-04-30 Beecham Group Plc 1,2,5,6-tetrahydropyridine oxime derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Also Published As

Publication number Publication date
IT1222526B (it) 1990-09-05
NO174504B (no) 1994-02-07
DE3867986D1 (de) 1992-03-05
ZA886131B (en) 1989-10-25
AU2110088A (en) 1989-02-23
IL87430A0 (en) 1989-01-31
PT88302B (pt) 1995-03-31
US4921868A (en) 1990-05-01
AU608643B2 (en) 1991-04-11
FI883869A (fi) 1989-02-22
ATE71938T1 (de) 1992-02-15
NO174504C (pt) 1994-05-18
FI883869A0 (fi) 1988-08-19
IE882538L (en) 1989-02-21
ES2038776T3 (es) 1993-08-01
IE61537B1 (en) 1994-11-16
IT8721687A0 (it) 1987-08-21
FI90070B (fi) 1993-09-15
SU1681723A3 (ru) 1991-09-30
KR960014998B1 (ko) 1996-10-23
KR890003692A (ko) 1989-04-17
FI90070C (fi) 1993-12-27
MX12707A (es) 1993-10-01
HU201012B (en) 1990-09-28
DK457388D0 (da) 1988-08-16
CA1340987C (fr) 2000-05-09
HU211913A9 (en) 1996-01-29
NZ225902A (en) 1990-06-26
NO883521L (no) 1989-02-22
NO883521D0 (no) 1988-08-08
JPH07107048B2 (ja) 1995-11-15
HUT49328A (en) 1989-09-28
EP0308283A1 (fr) 1989-03-22
EP0308283B1 (fr) 1992-01-22
DK457388A (da) 1989-02-22
JPS6468356A (en) 1989-03-14
GR3004249T3 (pt) 1993-03-31

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940908

PC3A Transfer or assignment

Free format text: 19991011 HOECHST MARION ROUSSEL FR

PD3A Change of proprietorship

Owner name: ROUSSEL UCLAF

Effective date: 19991011

TE3A Change of address (patent)

Owner name: ROUSSEL UCLAF

Effective date: 19991011

PC3A Transfer or assignment

Free format text: AVENTIS PHARMA S.A. FR

Effective date: 20030110

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040331