PT88301A - Processo para a preparacao de derivados de oxima de 1,2,5,6-tetraidropiridina e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de oxima de 1,2,5,6-tetraidropiridina e de composicoes farmaceuticas que os contem

Info

Publication number
PT88301A
PT88301A PT88301A PT8830188A PT88301A PT 88301 A PT88301 A PT 88301A PT 88301 A PT88301 A PT 88301A PT 8830188 A PT8830188 A PT 8830188A PT 88301 A PT88301 A PT 88301A
Authority
PT
Portugal
Prior art keywords
carbon atoms
linear
branched
alkynyl
alkenyl
Prior art date
Application number
PT88301A
Other languages
English (en)
Other versions
PT88301B (pt
Inventor
Emilio Toja
Fernando Barzaghi
Giulio Galliani
Carla Bonetti
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT88301A publication Critical patent/PT88301A/pt
Publication of PT88301B publication Critical patent/PT88301B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94Oxygen atom, e.g. piperidine N-oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
PT88301A 1987-08-21 1988-08-19 Processo para a preparacao de derivados de oxima de 1,2,5,6-tetraidropiridina e de composicoes farmaceuticas que os contem PT88301B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21691/87A IT1222529B (it) 1987-08-21 1987-08-21 Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali

Publications (2)

Publication Number Publication Date
PT88301A true PT88301A (pt) 1989-06-30
PT88301B PT88301B (pt) 1995-03-31

Family

ID=11185470

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88301A PT88301B (pt) 1987-08-21 1988-08-19 Processo para a preparacao de derivados de oxima de 1,2,5,6-tetraidropiridina e de composicoes farmaceuticas que os contem

Country Status (11)

Country Link
US (1) US4902699A (pt)
EP (1) EP0308284B1 (pt)
JP (1) JP2660430B2 (pt)
AT (1) ATE73445T1 (pt)
CA (1) CA1338494C (pt)
DE (1) DE3869028D1 (pt)
ES (1) ES2032582T3 (pt)
GR (1) GR3004652T3 (pt)
IT (1) IT1222529B (pt)
MX (1) MX12708A (pt)
PT (1) PT88301B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231107A (en) * 1987-08-21 1993-07-27 Roussel Uclaf Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them
DK177889A (da) * 1988-04-15 1989-10-16 Beecham Group Plc Hidtil ukendte forbindelser
IT1229491B (it) * 1988-12-28 1991-09-03 Roussel Maestretti S P A Ora R Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
EP0392803B1 (en) * 1989-04-13 2004-06-16 Beecham Group p.l.c. Novel compounds
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
JPH06500550A (ja) * 1990-08-24 1994-01-20 ビーチャム・グループ・パブリック・リミテッド・カンパニー アザ二環式化合物、その製造方法および製造用中間体ならびにその化合物含有の医薬組成物
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
JPH06501933A (ja) * 1990-10-12 1994-03-03 ビーチャム・グループ・パブリック・リミテッド・カンパニー 1,2,5,6−テトラヒドロピリジン・オキシム誘導体
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
AU1186300A (en) 1998-11-25 2000-06-13 Daiichi Radioisotope Laboratories, Ltd. Drugs and reagents containing n-acyloxylated cycloalkyl compounds as the active ingredient

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
CA725633A (en) * 1966-01-11 Dr. F. Raschig, G.M.B.H., Chemical Works Ethers of pyridine-aldoxime n-oxides
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents

Also Published As

Publication number Publication date
ATE73445T1 (de) 1992-03-15
IT8721691A0 (it) 1987-08-21
MX12708A (es) 1993-11-01
DE3869028D1 (de) 1992-04-16
JPH01110671A (ja) 1989-04-27
GR3004652T3 (pt) 1993-04-28
IT1222529B (it) 1990-09-05
US4902699A (en) 1990-02-20
EP0308284A1 (fr) 1989-03-22
CA1338494C (fr) 1996-07-30
PT88301B (pt) 1995-03-31
JP2660430B2 (ja) 1997-10-08
ES2032582T3 (es) 1993-02-16
EP0308284B1 (fr) 1992-03-11

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940908

PC3A Transfer or assignment

Free format text: 19991011 HOECHST MARION ROUSSEL FR

PD3A Change of proprietorship

Owner name: ROUSSEL UCLAF

Effective date: 19991011

TE3A Change of address (patent)

Owner name: ROUSSEL UCLAF

Effective date: 19991011

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20020331