ATE71938T1 - 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen. - Google Patents

1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen.

Info

Publication number
ATE71938T1
ATE71938T1 AT88402128T AT88402128T ATE71938T1 AT E71938 T1 ATE71938 T1 AT E71938T1 AT 88402128 T AT88402128 T AT 88402128T AT 88402128 T AT88402128 T AT 88402128T AT E71938 T1 ATE71938 T1 AT E71938T1
Authority
AT
Austria
Prior art keywords
carbon atoms
carboxaldehydoxim
tetrahydropyridine
derivatives
manufacture
Prior art date
Application number
AT88402128T
Other languages
English (en)
Inventor
Giulio Galliani
Fernando Barzaghi
Carla Bonetti
Emilio Toja
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of ATE71938T1 publication Critical patent/ATE71938T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT88402128T 1987-08-21 1988-08-19 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen. ATE71938T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8721687A IT1222526B (it) 1987-08-21 1987-08-21 Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
EP88402128A EP0308283B1 (de) 1987-08-21 1988-08-19 1,2,5,6-Tetrahydropyridin-3-carboxaldehydoxim-Derivate, Verfahren zu deren Herstellung, deren Verwendung als Arzneimittel und diese enthaltende Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE71938T1 true ATE71938T1 (de) 1992-02-15

Family

ID=11185397

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88402128T ATE71938T1 (de) 1987-08-21 1988-08-19 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen.

Country Status (22)

Country Link
US (1) US4921868A (de)
EP (1) EP0308283B1 (de)
JP (1) JPH07107048B2 (de)
KR (1) KR960014998B1 (de)
AT (1) ATE71938T1 (de)
AU (1) AU608643B2 (de)
CA (1) CA1340987C (de)
DE (1) DE3867986D1 (de)
DK (1) DK457388A (de)
ES (1) ES2038776T3 (de)
FI (1) FI90070C (de)
GR (1) GR3004249T3 (de)
HU (2) HU201012B (de)
IE (1) IE61537B1 (de)
IL (1) IL87430A0 (de)
IT (1) IT1222526B (de)
MX (1) MX12707A (de)
NO (1) NO174504B (de)
NZ (1) NZ225902A (de)
PT (1) PT88302B (de)
SU (1) SU1681723A3 (de)
ZA (1) ZA886131B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231107A (en) * 1987-08-21 1993-07-27 Roussel Uclaf Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them
AU3301689A (en) * 1988-04-15 1989-10-26 Beecham Group Plc 1-azabicyclo-alkyl derivatives
SG48315A1 (en) * 1989-04-13 1998-04-17 Beecham Group Plc Novel compounds
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
PT98742A (pt) * 1990-08-24 1992-07-31 Beecham Group Plc Processo para a preparacao de compostos azabicilicos
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
JPH06501933A (ja) * 1990-10-12 1994-03-03 ビーチャム・グループ・パブリック・リミテッド・カンパニー １，２，５，６−テトラヒドロピリジン・オキシム誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Also Published As

Publication number Publication date
EP0308283A1 (de) 1989-03-22
IE61537B1 (en) 1994-11-16
AU2110088A (en) 1989-02-23
FI90070C (fi) 1993-12-27
SU1681723A3 (ru) 1991-09-30
NO174504B (no) 1994-02-07
PT88302B (pt) 1995-03-31
IE882538L (en) 1989-02-21
JPH07107048B2 (ja) 1995-11-15
PT88302A (pt) 1989-09-14
JPS6468356A (en) 1989-03-14
US4921868A (en) 1990-05-01
CA1340987C (fr) 2000-05-09
DK457388D0 (da) 1988-08-16
ES2038776T3 (es) 1993-08-01
NO883521D0 (no) 1988-08-08
KR890003692A (ko) 1989-04-17
IT1222526B (it) 1990-09-05
HU201012B (en) 1990-09-28
ZA886131B (en) 1989-10-25
NO883521L (no) 1989-02-22
GR3004249T3 (de) 1993-03-31
IT8721687A0 (it) 1987-08-21
NZ225902A (en) 1990-06-26
IL87430A0 (en) 1989-01-31
HU211913A9 (en) 1996-01-29
HUT49328A (en) 1989-09-28
DK457388A (da) 1989-02-22
NO174504C (de) 1994-05-18
FI883869A0 (fi) 1988-08-19
MX12707A (es) 1993-10-01
DE3867986D1 (de) 1992-03-05
FI90070B (fi) 1993-09-15
EP0308283B1 (de) 1992-01-22
KR960014998B1 (ko) 1996-10-23
AU608643B2 (en) 1991-04-11
FI883869A (fi) 1989-02-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee