ATE80387T1 - 1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten. - Google Patents

1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten.

Info

Publication number
ATE80387T1
ATE80387T1 AT88400996T AT88400996T ATE80387T1 AT E80387 T1 ATE80387 T1 AT E80387T1 AT 88400996 T AT88400996 T AT 88400996T AT 88400996 T AT88400996 T AT 88400996T AT E80387 T1 ATE80387 T1 AT E80387T1
Authority
AT
Austria
Prior art keywords
denotes
manufacture
compositions containing
medicinal use
alkyl
Prior art date
Application number
AT88400996T
Other languages
English (en)
Inventor
Giulio Galliani
Fernando Barzaghi
Carla Bonetti
Emilio Toja
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of ATE80387T1 publication Critical patent/ATE80387T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88400996T 1987-04-24 1988-04-22 1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten. ATE80387T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20260/87A IT1203971B (it) 1987-04-24 1987-04-24 Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
EP88400996A EP0288394B1 (de) 1987-04-24 1988-04-22 1,2,5,6-Tetrahydropyridin-Derivate, Verfahren zur Herstellung, Verwendung als Heilmittel und Zusammenstellungen, die sie enthalten

Publications (1)

Publication Number Publication Date
ATE80387T1 true ATE80387T1 (de) 1992-09-15

Family

ID=11165225

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88400996T ATE80387T1 (de) 1987-04-24 1988-04-22 1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten.

Country Status (22)

Country Link
EP (1) EP0288394B1 (de)
JP (1) JP2727192B2 (de)
KR (1) KR960012365B1 (de)
AT (1) ATE80387T1 (de)
AU (1) AU614283B2 (de)
CA (1) CA1340986C (de)
DE (1) DE3874396T2 (de)
DK (1) DK167758B1 (de)
ES (1) ES2043863T3 (de)
FI (1) FI93211C (de)
GR (1) GR3005647T3 (de)
HU (1) HU199795B (de)
IE (1) IE63172B1 (de)
IL (1) IL86157A (de)
IT (1) IT1203971B (de)
MX (1) MX11201A (de)
NZ (1) NZ224357A (de)
OA (1) OA08835A (de)
PH (1) PH25574A (de)
PT (1) PT87290B (de)
SU (1) SU1678203A3 (de)
ZA (1) ZA882595B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
DK177889A (da) * 1988-04-15 1989-10-16 Beecham Group Plc Hidtil ukendte forbindelser
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
EP0392803B1 (de) * 1989-04-13 2004-06-16 Beecham Group p.l.c. Chemische Verbindungen
JPH06500550A (ja) * 1990-08-24 1994-01-20 ビーチャム・グループ・パブリック・リミテッド・カンパニー アザ二環式化合物、その製造方法および製造用中間体ならびにその化合物含有の医薬組成物
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
JPH06501933A (ja) * 1990-10-12 1994-03-03 ビーチャム・グループ・パブリック・リミテッド・カンパニー １，２，５，６−テトラヒドロピリジン・オキシム誘導体
CA2080536A1 (en) * 1991-10-17 1993-04-18 John S. Ward Nicotinic activity of a series of arecolones and isoarecolones
WO1993011767A1 (en) * 1991-12-18 1993-06-24 Warner-Lambert Company Transdermal delivery of (e)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-o-methyloxine hcl and related compounds in the treatment of cognitive disorders and for analgesia
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5362860A (en) * 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
US6250886B1 (en) 1999-09-03 2001-06-26 Chittom International, Inc. Axial flow fan and fan blade

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
JPH0641332B2 (ja) * 1986-09-17 1994-06-01 株式会社共同精機工作所 断裁機へのシ−ト類供給装置
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment

Also Published As

Publication number Publication date
HUT47248A (en) 1989-02-28
AU614283B2 (en) 1991-08-29
GR3005647T3 (de) 1993-06-07
IT8720260A0 (it) 1987-04-24
ZA882595B (en) 1989-07-26
IE881207L (en) 1988-10-24
SU1678203A3 (ru) 1991-09-15
HU199795B (en) 1990-03-28
MX11201A (es) 1993-10-01
JPS63284160A (ja) 1988-11-21
AU1511188A (en) 1988-10-27
DK216388A (da) 1988-10-25
KR890016009A (ko) 1989-11-27
FI93211B (fi) 1994-11-30
DK167758B1 (da) 1993-12-13
CA1340986C (fr) 2000-05-09
DK216388D0 (da) 1988-04-21
KR960012365B1 (ko) 1996-09-20
DE3874396T2 (de) 1993-04-22
ES2043863T3 (es) 1994-01-01
PH25574A (en) 1991-08-08
FI881892A (fi) 1988-10-25
PT87290A (pt) 1988-05-01
OA08835A (fr) 1989-03-31
IL86157A0 (en) 1988-11-15
IE63172B1 (en) 1995-03-22
EP0288394A2 (de) 1988-10-26
FI93211C (fi) 1995-03-10
EP0288394A3 (en) 1989-01-25
JP2727192B2 (ja) 1998-03-11
FI881892A0 (fi) 1988-04-22
PT87290B (pt) 1992-08-31
IT1203971B (it) 1989-02-23
IL86157A (en) 1994-04-12
DE3874396D1 (de) 1992-10-15
EP0288394B1 (de) 1992-09-09
NZ224357A (en) 1992-01-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee