DE3874396D1 - 1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten. - Google Patents

1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten.

Info

Publication number
DE3874396D1
DE3874396D1 DE8888400996T DE3874396T DE3874396D1 DE 3874396 D1 DE3874396 D1 DE 3874396D1 DE 8888400996 T DE8888400996 T DE 8888400996T DE 3874396 T DE3874396 T DE 3874396T DE 3874396 D1 DE3874396 D1 DE 3874396D1
Authority
DE
Germany
Prior art keywords
denotes
compositions
production
medicinal product
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888400996T
Other languages
English (en)
Other versions
DE3874396T2 (de
Inventor
Giulio Galliani
Fernando Barzaghi
Carla Bonetti
Emilio Toja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of DE3874396D1 publication Critical patent/DE3874396D1/de
Application granted granted Critical
Publication of DE3874396T2 publication Critical patent/DE3874396T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide
DE8888400996T 1987-04-24 1988-04-22 1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten. Expired - Fee Related DE3874396T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20260/87A IT1203971B (it) 1987-04-24 1987-04-24 Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Publications (2)

Publication Number Publication Date
DE3874396D1 true DE3874396D1 (de) 1992-10-15
DE3874396T2 DE3874396T2 (de) 1993-04-22

Family

ID=11165225

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888400996T Expired - Fee Related DE3874396T2 (de) 1987-04-24 1988-04-22 1,2,5,6-tetrahydropyridin-derivate, verfahren zur herstellung, verwendung als heilmittel und zusammenstellungen, die sie enthalten.

Country Status (22)

Country Link
EP (1) EP0288394B1 (de)
JP (1) JP2727192B2 (de)
KR (1) KR960012365B1 (de)
AT (1) ATE80387T1 (de)
AU (1) AU614283B2 (de)
CA (1) CA1340986C (de)
DE (1) DE3874396T2 (de)
DK (1) DK167758B1 (de)
ES (1) ES2043863T3 (de)
FI (1) FI93211C (de)
GR (1) GR3005647T3 (de)
HU (1) HU199795B (de)
IE (1) IE63172B1 (de)
IL (1) IL86157A (de)
IT (1) IT1203971B (de)
MX (1) MX11201A (de)
NZ (1) NZ224357A (de)
OA (1) OA08835A (de)
PH (1) PH25574A (de)
PT (1) PT87290B (de)
SU (1) SU1678203A3 (de)
ZA (1) ZA882595B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
DK177889A (da) * 1988-04-15 1989-10-16 Beecham Group Plc Hidtil ukendte forbindelser
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
ES2219636T3 (es) * 1989-04-13 2004-12-01 Beecham Group P.L.C. Nuevos compuestos.
AU8436291A (en) * 1990-08-24 1992-03-17 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
US5356914A (en) * 1990-10-12 1994-10-18 Beecham Group P.L.C. 1,2,5,6-tetrahydropyridine oxime derivatives
EP0537993A1 (de) * 1991-10-17 1993-04-21 Eli Lilly And Company Nikotina-Rezeptoraktivität eine Reihe von Arecolonen und Isoarecolonen
AU3142793A (en) * 1991-12-18 1993-07-19 Warner-Lambert Company Transdermal delivery of (E)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-O- methyloxine HCL and related compounds in the treatment of cognitive disorders and for analgesia
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5362860A (en) * 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
US6250886B1 (en) 1999-09-03 2001-06-26 Chittom International, Inc. Axial flow fan and fan blade

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
JPH0641332B2 (ja) * 1986-09-17 1994-06-01 株式会社共同精機工作所 断裁機へのシ−ト類供給装置
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment

Also Published As

Publication number Publication date
HUT47248A (en) 1989-02-28
NZ224357A (en) 1992-01-29
IE881207L (en) 1988-10-24
EP0288394A2 (de) 1988-10-26
FI93211B (fi) 1994-11-30
EP0288394B1 (de) 1992-09-09
DK216388A (da) 1988-10-25
DK216388D0 (da) 1988-04-21
PT87290B (pt) 1992-08-31
PH25574A (en) 1991-08-08
PT87290A (pt) 1988-05-01
KR960012365B1 (ko) 1996-09-20
IE63172B1 (en) 1995-03-22
IT1203971B (it) 1989-02-23
FI93211C (fi) 1995-03-10
ATE80387T1 (de) 1992-09-15
ZA882595B (en) 1989-07-26
SU1678203A3 (ru) 1991-09-15
HU199795B (en) 1990-03-28
AU1511188A (en) 1988-10-27
FI881892A0 (fi) 1988-04-22
EP0288394A3 (en) 1989-01-25
FI881892A (fi) 1988-10-25
GR3005647T3 (de) 1993-06-07
AU614283B2 (en) 1991-08-29
CA1340986C (fr) 2000-05-09
KR890016009A (ko) 1989-11-27
IL86157A (en) 1994-04-12
DK167758B1 (da) 1993-12-13
IL86157A0 (en) 1988-11-15
MX11201A (es) 1993-10-01
IT8720260A0 (it) 1987-04-24
OA08835A (fr) 1989-03-31
DE3874396T2 (de) 1993-04-22
JPS63284160A (ja) 1988-11-21
JP2727192B2 (ja) 1998-03-11
ES2043863T3 (es) 1994-01-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HOECHST MARION ROUSSEL, PUTEAUX, FR

8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMA S.A., ANTONY CEDEX, FR

8339 Ceased/non-payment of the annual fee