ATE7492T1 - Verfahren zur herstellung von 4-aminochlorchinolinen. - Google Patents

Verfahren zur herstellung von 4-aminochlorchinolinen.

Info

Publication number
ATE7492T1
ATE7492T1 AT82400080T AT82400080T ATE7492T1 AT E7492 T1 ATE7492 T1 AT E7492T1 AT 82400080 T AT82400080 T AT 82400080T AT 82400080 T AT82400080 T AT 82400080T AT E7492 T1 ATE7492 T1 AT E7492T1
Authority
AT
Austria
Prior art keywords
formula
image
optionally substituted
carbon atoms
amino
Prior art date
Application number
AT82400080T
Other languages
English (en)
Inventor
Michel Baudouin
Daniel Michelet
Original Assignee
Rhone-Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone-Poulenc Sante filed Critical Rhone-Poulenc Sante
Application granted granted Critical
Publication of ATE7492T1 publication Critical patent/ATE7492T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/46Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT82400080T 1981-01-16 1982-01-15 Verfahren zur herstellung von 4-aminochlorchinolinen. ATE7492T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8100765A FR2498187A1 (fr) 1981-01-16 1981-01-16 Procede de preparation d'amino-4 chloro-7 quinoleines
EP82400080A EP0056766B1 (de) 1981-01-16 1982-01-15 Verfahren zur Herstellung von 4-Amino-chlorchinolinen

Publications (1)

Publication Number Publication Date
ATE7492T1 true ATE7492T1 (de) 1984-06-15

Family

ID=9254223

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82400080T ATE7492T1 (de) 1981-01-16 1982-01-15 Verfahren zur herstellung von 4-aminochlorchinolinen.

Country Status (13)

Country Link
US (1) US4421920A (de)
EP (1) EP0056766B1 (de)
JP (1) JPS57171973A (de)
KR (1) KR870001921B1 (de)
AT (1) ATE7492T1 (de)
CA (1) CA1171861A (de)
DE (1) DE3260150D1 (de)
DK (1) DK148805C (de)
FR (1) FR2498187A1 (de)
HU (1) HU184985B (de)
IE (1) IE51957B1 (de)
IN (1) IN158327B (de)
ZA (1) ZA82277B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2892298A (en) * 1957-08-05 1959-06-30 Earl J Chaney Pickup device
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
WO1986006718A1 (en) * 1985-05-17 1986-11-20 The Australian National University Antimalarial compounds
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
CA1340821C (en) * 1988-10-06 1999-11-16 Nobuyuki Fukazawa Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
CA2133620A1 (en) * 1993-10-28 1995-04-29 Werner Hofheinz Aminoquinoline derivatives
WO1996040138A1 (en) * 1995-06-07 1996-12-19 The Administrators Of The Tulane Educational Fund Chloroquine analogs and methods of preventing and treating plasmodial disease
DE69709319T2 (de) 1996-03-05 2002-08-14 Astrazeneca Ab 4-anilinochinazolin derivate
JP2001500890A (ja) * 1996-09-25 2001-01-23 ゼネカ リミテッド Vegfのような成長因子の作用を阻害するキノリン誘導体
GB9910579D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910580D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
CA2416233A1 (en) 1999-07-13 2001-01-18 Alpha Research Group, Llc Compositions and methods for the treatment of parkinson's disease
US20040229908A1 (en) * 1999-07-13 2004-11-18 Jodi Nelson Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias
AU779695B2 (en) * 2000-04-07 2005-02-10 Astrazeneca Ab Quinazoline compounds
WO2002044166A1 (en) * 2000-11-02 2002-06-06 Astrazeneca Ab Substituted quinolines as antitumor agents
JP2004517059A (ja) * 2000-11-02 2004-06-10 アストラゼネカ アクチボラグ 抗腫瘍剤用の4−置換キノリン類
US7084157B2 (en) * 2002-05-17 2006-08-01 Rajeev Raut Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation
US20040002451A1 (en) * 2002-06-20 2004-01-01 Bruce Kerwin Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
GB0215823D0 (en) * 2002-07-09 2002-08-14 Astrazeneca Ab Quinazoline derivatives
GB0225579D0 (en) * 2002-11-02 2002-12-11 Astrazeneca Ab Chemical compounds
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US7108992B2 (en) * 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
WO2005003100A2 (en) 2003-07-03 2005-01-13 Myriad Genetics, Inc. 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
WO2006074147A2 (en) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
BRPI0418102A (pt) * 2003-12-23 2007-04-27 Pfizer derivados de quinolina
ES2237332B1 (es) * 2004-01-14 2006-11-01 Consejo Sup. Investig. Cientificas Derivados de piridinio y quinolinio.
US8586613B2 (en) 2004-01-14 2013-11-19 Universidad De Granada Pyridinium and quinolinium derivatives
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US8440695B2 (en) * 2005-11-09 2013-05-14 St Jude Children's Research Hospital Use of chloroquine to treat metabolic syndrome
CN105693606B (zh) * 2016-03-09 2017-12-05 西安科技大学 一种光学纯(r)/(s)‑羟氯喹的不对称合成方法
CN105693605B (zh) * 2016-03-09 2017-12-22 西安科技大学 一种光学纯(r)/(s)‑氯喹的不对称合成方法
WO2022112596A1 (en) 2020-11-30 2022-06-02 Cellectis Sa Use of aminoquinoline compounds for higher gene integration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653940A (en) * 1951-01-27 1953-09-29 William S Johnson Process for preparing 4-quinolyl secondary amines

Also Published As

Publication number Publication date
HU184985B (en) 1984-11-28
ZA82277B (en) 1982-11-24
KR870001921B1 (ko) 1987-10-22
IE820075L (en) 1982-07-16
IN158327B (de) 1986-10-18
DK16582A (da) 1982-07-17
IE51957B1 (en) 1987-04-29
DK148805C (da) 1986-04-01
DE3260150D1 (en) 1984-06-20
EP0056766B1 (de) 1984-05-16
EP0056766A1 (de) 1982-07-28
JPS57171973A (en) 1982-10-22
FR2498187B1 (de) 1983-09-30
KR830009038A (ko) 1983-12-17
DK148805B (da) 1985-10-07
FR2498187A1 (fr) 1982-07-23
US4421920A (en) 1983-12-20
CA1171861A (fr) 1984-07-31

Similar Documents

Publication Publication Date Title
ATE7492T1 (de) Verfahren zur herstellung von 4-aminochlorchinolinen.
KR830009094A (ko) 9-[2-(3-인돌일)에틸]-1-옥사-4.9-디아자스피로[5.5]운데칸-3-온류의 제조방법
KR850004492A (ko) 옥시캄의 엔올 에테르 유도체의 제조방법
DE3575715D1 (de) Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel.
DE59509910D1 (de) Verfahren zur Herstellung von Alkylhydrogenchlorsilanen
ATE9469T1 (de) Reaktive derivate des 3-oxa-bicyclo(4.3.0)-non-1- en-9-ons, verfahren zu ihrer herstellung und deren verwendung.
PT74470B (de) Chemische verbindungen verfahren zu ihrer herstellung und ihre verwendungen als antigene oder immunadsorbentien
GR77667B (de)
DK50383A (da) Fremgangsmaade til fremstilling af 4-piperazinyl-4-phenyl-quinazolin-derivater
ES2045282T3 (es) Un procedimiento para la preparacion de antraciclinona 4-sustituida.
RO87991A (ro) Procedeu pentru prepararea unor esteri tiazolidinici substituiti ai unor acizi minerali
ES538896A0 (es) Procedimiento de preparar derivados de fenilalanina
EP0481370A3 (en) Use of phosphonic acid diglycidylesters as cross-linking agent in hydrogels
DE69839732D1 (de) Verfahren zur herstellung von 3,4-dihydroxy-3cyclobuten-1,2-dion
FI873443A (fi) Norfloxacinmellanprodukt.
GB2020659B (en) Derivatives of 1,5-dimethylbicyclo (3.2.1) octane
KR840002821A (ko) N-(2,3-에폭시프로필렌)-n-아르알킬술폰아미드 유도체의 제조방법
ATE16696T1 (de) Verfahren zur herstellung von 3-alkyl-6-methylbeta-resorcylsaeureestern.
ES481486A1 (es) Procedimientos para preparar derivados de acidos 1-pirrol- carboxilixos
PT87819A (pt) Procede de preparation de nouveaux derives de la 1-benzoyl 2-oxo 5-alcoxy pyrrolidine
IL65666A (en) Derivatives of 4-aminomethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones and process for their preparation
JPS6483032A (en) Manufacture of diene-1-ol, 9-hydroxydodecene- (10)-yl-1 tertiary butyl ether and use
IL65667A (en) 4-(4-phenyl-1-piperidinyl)methyl-5-benzoyl-1,3-dihydro-2h-imidazol-2-one derivatives and process for their preparation
ATE29253T1 (de) Verfahren zur herstellung von 4-chinolinonen.
DE68926016D1 (de) Halogeno-4-Methylpyrazole und Verfahren zu ihrer Herstellung