DK16582A - Fremgangsmaade til fremstilling af 4-aminochlorquinoliner - Google Patents

Fremgangsmaade til fremstilling af 4-aminochlorquinoliner Download PDF

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Publication number
DK16582A
DK16582A DK16582A DK16582A DK16582A DK 16582 A DK16582 A DK 16582A DK 16582 A DK16582 A DK 16582A DK 16582 A DK16582 A DK 16582A DK 16582 A DK16582 A DK 16582A
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DK
Denmark
Prior art keywords
formula
image
optionally substituted
carbon atoms
amino
Prior art date
Application number
DK16582A
Other languages
English (en)
Other versions
DK148805C (da
DK148805B (da
Inventor
M Baudouin
D Michelet
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of DK16582A publication Critical patent/DK16582A/da
Publication of DK148805B publication Critical patent/DK148805B/da
Application granted granted Critical
Publication of DK148805C publication Critical patent/DK148805C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/46Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK16582A 1981-01-16 1982-01-15 Fremgangsmaade til fremstilling af 4-aminochlorquinoliner DK148805C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8100765A FR2498187A1 (fr) 1981-01-16 1981-01-16 Procede de preparation d'amino-4 chloro-7 quinoleines
FR8100765 1981-01-16

Publications (3)

Publication Number Publication Date
DK16582A true DK16582A (da) 1982-07-17
DK148805B DK148805B (da) 1985-10-07
DK148805C DK148805C (da) 1986-04-01

Family

ID=9254223

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16582A DK148805C (da) 1981-01-16 1982-01-15 Fremgangsmaade til fremstilling af 4-aminochlorquinoliner

Country Status (13)

Country Link
US (1) US4421920A (da)
EP (1) EP0056766B1 (da)
JP (1) JPS57171973A (da)
KR (1) KR870001921B1 (da)
AT (1) ATE7492T1 (da)
CA (1) CA1171861A (da)
DE (1) DE3260150D1 (da)
DK (1) DK148805C (da)
FR (1) FR2498187A1 (da)
HU (1) HU184985B (da)
IE (1) IE51957B1 (da)
IN (1) IN158327B (da)
ZA (1) ZA82277B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2892298A (en) * 1957-08-05 1959-06-30 Earl J Chaney Pickup device

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
WO1986006718A1 (en) * 1985-05-17 1986-11-20 The Australian National University Antimalarial compounds
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
CA1340821C (en) * 1988-10-06 1999-11-16 Nobuyuki Fukazawa Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
CA2133620A1 (en) * 1993-10-28 1995-04-29 Werner Hofheinz Aminoquinoline derivatives
AU6168296A (en) * 1995-06-07 1996-12-30 The Administrators Of The Tulane Eductional Fund Chloroquine analogs and methods of preventing and treating p lasmodial disease
KR100489174B1 (ko) 1996-03-05 2005-09-30 제네카-파마 소시에떼아노님 4-아닐리노퀴나졸린유도체
KR100567649B1 (ko) * 1996-09-25 2006-04-05 아스트라제네카 유케이 리미티드 혈관 내피 성장 인자와 같은 성장 인자의 효과를 억제하는 퀴놀린 유도체
GB9910579D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910580D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
US20040229908A1 (en) * 1999-07-13 2004-11-18 Jodi Nelson Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias
ATE431141T1 (de) 1999-07-13 2009-05-15 Alpha Res Group Llc Zusammensetzungen und verfahren zur behandlung der parkinson-krankheit
MXPA02009891A (es) * 2000-04-07 2003-03-27 Astrazeneca Ab Compuestos de quinazolina.
WO2002036570A1 (en) * 2000-11-02 2002-05-10 Astrazeneca Ab 4-substituted quinolines as antitumor agents
US7067532B2 (en) * 2000-11-02 2006-06-27 Astrazeneca Substituted quinolines as antitumor agents
US7084157B2 (en) * 2002-05-17 2006-08-01 Rajeev Raut Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation
US20040002451A1 (en) * 2002-06-20 2004-01-01 Bruce Kerwin Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
GB0215823D0 (en) * 2002-07-09 2002-08-14 Astrazeneca Ab Quinazoline derivatives
GB0225579D0 (en) * 2002-11-02 2002-12-11 Astrazeneca Ab Chemical compounds
US7108992B2 (en) * 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
US7618975B2 (en) 2003-07-03 2009-11-17 Myriad Pharmaceuticals, Inc. 4-arylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
CN1890234A (zh) * 2003-12-23 2007-01-03 辉瑞大药厂 新颖的喹啉衍生物
ES2237332B1 (es) * 2004-01-14 2006-11-01 Consejo Sup. Investig. Cientificas Derivados de piridinio y quinolinio.
US8586613B2 (en) 2004-01-14 2013-11-19 Universidad De Granada Pyridinium and quinolinium derivatives
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
CA2592900A1 (en) 2005-01-03 2006-07-13 Myriad Genetics Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
WO2007059372A2 (en) * 2005-11-09 2007-05-24 St. Jude Children's Research Hospital Use of chloroquine to treat metabolic syndrome
CN105693606B (zh) * 2016-03-09 2017-12-05 西安科技大学 一种光学纯(r)/(s)‑羟氯喹的不对称合成方法
CN105693605B (zh) * 2016-03-09 2017-12-22 西安科技大学 一种光学纯(r)/(s)‑氯喹的不对称合成方法
EP4251746A1 (en) 2020-11-30 2023-10-04 Cellectis SA Use of aminoquinoline compounds for higher gene integration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653940A (en) * 1951-01-27 1953-09-29 William S Johnson Process for preparing 4-quinolyl secondary amines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2892298A (en) * 1957-08-05 1959-06-30 Earl J Chaney Pickup device

Also Published As

Publication number Publication date
FR2498187B1 (da) 1983-09-30
DE3260150D1 (en) 1984-06-20
ZA82277B (en) 1982-11-24
DK148805C (da) 1986-04-01
DK148805B (da) 1985-10-07
CA1171861A (fr) 1984-07-31
IE51957B1 (en) 1987-04-29
FR2498187A1 (fr) 1982-07-23
IN158327B (da) 1986-10-18
JPS57171973A (en) 1982-10-22
HU184985B (en) 1984-11-28
KR870001921B1 (ko) 1987-10-22
KR830009038A (ko) 1983-12-17
ATE7492T1 (de) 1984-06-15
IE820075L (en) 1982-07-16
EP0056766A1 (fr) 1982-07-28
US4421920A (en) 1983-12-20
EP0056766B1 (fr) 1984-05-16

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