DE3260150D1 - Process for the preparation of 4-amino-chloroquinolines - Google Patents
Process for the preparation of 4-amino-chloroquinolinesInfo
- Publication number
- DE3260150D1 DE3260150D1 DE8282400080T DE3260150T DE3260150D1 DE 3260150 D1 DE3260150 D1 DE 3260150D1 DE 8282400080 T DE8282400080 T DE 8282400080T DE 3260150 T DE3260150 T DE 3260150T DE 3260150 D1 DE3260150 D1 DE 3260150D1
- Authority
- DE
- Germany
- Prior art keywords
- amino
- formula
- image
- optionally substituted
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8100765A FR2498187A1 (fr) | 1981-01-16 | 1981-01-16 | Procede de preparation d'amino-4 chloro-7 quinoleines |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3260150D1 true DE3260150D1 (en) | 1984-06-20 |
Family
ID=9254223
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8282400080T Expired DE3260150D1 (en) | 1981-01-16 | 1982-01-15 | Process for the preparation of 4-amino-chloroquinolines |
Country Status (13)
Country | Link |
---|---|
US (1) | US4421920A (de) |
EP (1) | EP0056766B1 (de) |
JP (1) | JPS57171973A (de) |
KR (1) | KR870001921B1 (de) |
AT (1) | ATE7492T1 (de) |
CA (1) | CA1171861A (de) |
DE (1) | DE3260150D1 (de) |
DK (1) | DK148805C (de) |
FR (1) | FR2498187A1 (de) |
HU (1) | HU184985B (de) |
IE (1) | IE51957B1 (de) |
IN (1) | IN158327B (de) |
ZA (1) | ZA82277B (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2892298A (en) * | 1957-08-05 | 1959-06-30 | Earl J Chaney | Pickup device |
GB8426584D0 (en) * | 1984-10-19 | 1984-11-28 | Beecham Group Plc | Compounds |
EP0222839A4 (de) * | 1985-05-17 | 1988-11-09 | Univ Australian | Antimalariaverbindungen. |
US4789678A (en) * | 1986-08-25 | 1988-12-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds |
CA1340821C (en) * | 1988-10-06 | 1999-11-16 | Nobuyuki Fukazawa | Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components |
PT100905A (pt) * | 1991-09-30 | 1994-02-28 | Eisai Co Ltd | Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem |
CA2133620A1 (en) * | 1993-10-28 | 1995-04-29 | Werner Hofheinz | Aminoquinoline derivatives |
AU6168296A (en) * | 1995-06-07 | 1996-12-30 | The Administrators Of The Tulane Eductional Fund | Chloroquine analogs and methods of preventing and treating p lasmodial disease |
NZ331191A (en) | 1996-03-05 | 2000-03-27 | Zeneca Ltd | 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof |
DE69733825T2 (de) * | 1996-09-25 | 2006-06-08 | Astrazeneca Ab | Chinolin-derivate die den effekt von wachstumsfaktoren wie vegf vezögern |
GB9910579D0 (en) | 1999-05-08 | 1999-07-07 | Zeneca Ltd | Chemical compounds |
GB9910580D0 (en) | 1999-05-08 | 1999-07-07 | Zeneca Ltd | Chemical compounds |
US20040229908A1 (en) * | 1999-07-13 | 2004-11-18 | Jodi Nelson | Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias |
EP1261340B1 (de) | 1999-07-13 | 2009-05-13 | Alpha Research Group, LLC | Zusammensetzungen und verfahren zur behandlung der parkinson-krankheit |
AU779695B2 (en) * | 2000-04-07 | 2005-02-10 | Astrazeneca Ab | Quinazoline compounds |
WO2002044166A1 (en) * | 2000-11-02 | 2002-06-06 | Astrazeneca Ab | Substituted quinolines as antitumor agents |
WO2002036570A1 (en) * | 2000-11-02 | 2002-05-10 | Astrazeneca Ab | 4-substituted quinolines as antitumor agents |
US7084157B2 (en) * | 2002-05-17 | 2006-08-01 | Rajeev Raut | Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation |
US20040002451A1 (en) * | 2002-06-20 | 2004-01-01 | Bruce Kerwin | Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing |
GB0215823D0 (en) * | 2002-07-09 | 2002-08-14 | Astrazeneca Ab | Quinazoline derivatives |
GB0225579D0 (en) * | 2002-11-02 | 2002-12-11 | Astrazeneca Ab | Chemical compounds |
US7108992B2 (en) * | 2002-11-27 | 2006-09-19 | St. Jude Children's Research Hospital | ATM kinase compositions and methods |
US6916627B2 (en) * | 2002-11-27 | 2005-07-12 | St. Jude Children's Research Hospital | ATM kinase compositions and methods |
US8309562B2 (en) * | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
AU2004253967B2 (en) | 2003-07-03 | 2010-02-18 | Cytovia, Inc. | 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis |
JP4503022B2 (ja) * | 2003-12-23 | 2010-07-14 | ファイザー・インク | 新規キノリン誘導体 |
US8586613B2 (en) | 2004-01-14 | 2013-11-19 | Universidad De Granada | Pyridinium and quinolinium derivatives |
ES2237332B1 (es) * | 2004-01-14 | 2006-11-01 | Consejo Sup. Investig. Cientificas | Derivados de piridinio y quinolinio. |
US8258145B2 (en) * | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
US8440695B2 (en) * | 2005-11-09 | 2013-05-14 | St Jude Children's Research Hospital | Use of chloroquine to treat metabolic syndrome |
CN105693606B (zh) * | 2016-03-09 | 2017-12-05 | 西安科技大学 | 一种光学纯(r)/(s)‑羟氯喹的不对称合成方法 |
CN105693605B (zh) * | 2016-03-09 | 2017-12-22 | 西安科技大学 | 一种光学纯(r)/(s)‑氯喹的不对称合成方法 |
EP4251746A1 (de) | 2020-11-30 | 2023-10-04 | Cellectis SA | Verwendung von aminochinolinverbindungen zur höheren genintegration |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2653940A (en) * | 1951-01-27 | 1953-09-29 | William S Johnson | Process for preparing 4-quinolyl secondary amines |
-
1981
- 1981-01-16 FR FR8100765A patent/FR2498187A1/fr active Granted
-
1982
- 1982-01-14 JP JP57003535A patent/JPS57171973A/ja active Pending
- 1982-01-15 IE IE75/82A patent/IE51957B1/en unknown
- 1982-01-15 IN IN36/DEL/82A patent/IN158327B/en unknown
- 1982-01-15 AT AT82400080T patent/ATE7492T1/de active
- 1982-01-15 DK DK16582A patent/DK148805C/da not_active IP Right Cessation
- 1982-01-15 ZA ZA82277A patent/ZA82277B/xx unknown
- 1982-01-15 KR KR8200161A patent/KR870001921B1/ko active
- 1982-01-15 CA CA000394273A patent/CA1171861A/fr not_active Expired
- 1982-01-15 US US06/339,722 patent/US4421920A/en not_active Expired - Fee Related
- 1982-01-15 HU HU82121A patent/HU184985B/hu not_active IP Right Cessation
- 1982-01-15 EP EP82400080A patent/EP0056766B1/de not_active Expired
- 1982-01-15 DE DE8282400080T patent/DE3260150D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
KR830009038A (ko) | 1983-12-17 |
JPS57171973A (en) | 1982-10-22 |
ATE7492T1 (de) | 1984-06-15 |
ZA82277B (en) | 1982-11-24 |
CA1171861A (fr) | 1984-07-31 |
IN158327B (de) | 1986-10-18 |
FR2498187A1 (fr) | 1982-07-23 |
EP0056766B1 (de) | 1984-05-16 |
HU184985B (en) | 1984-11-28 |
DK148805B (da) | 1985-10-07 |
DK16582A (da) | 1982-07-17 |
DK148805C (da) | 1986-04-01 |
US4421920A (en) | 1983-12-20 |
IE51957B1 (en) | 1987-04-29 |
KR870001921B1 (ko) | 1987-10-22 |
IE820075L (en) | 1982-07-16 |
FR2498187B1 (de) | 1983-09-30 |
EP0056766A1 (de) | 1982-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |