JPS56110693A - Allylcarboxylic acid derivative - Google Patents
Allylcarboxylic acid derivativeInfo
- Publication number
- JPS56110693A JPS56110693A JP1417080A JP1417080A JPS56110693A JP S56110693 A JPS56110693 A JP S56110693A JP 1417080 A JP1417080 A JP 1417080A JP 1417080 A JP1417080 A JP 1417080A JP S56110693 A JPS56110693 A JP S56110693A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- give
- reacted
- acid derivative
- synthesizing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- GSLDEZOOOSBFGP-UHFFFAOYSA-N alpha-methylene gamma-butyrolactone Chemical compound C=C1CCOC1=O GSLDEZOOOSBFGP-UHFFFAOYSA-N 0.000 abstract 2
- 230000002194 synthesizing effect Effects 0.000 abstract 2
- 101710112752 Cytotoxin Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005336 allyloxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 239000002619 cytotoxin Substances 0.000 abstract 1
- FJBFPHVGVWTDIP-UHFFFAOYSA-N dibromomethane Chemical compound BrCBr FJBFPHVGVWTDIP-UHFFFAOYSA-N 0.000 abstract 1
- BEPAFCGSDWSTEL-UHFFFAOYSA-N dimethyl malonate Chemical compound COC(=O)CC(=O)OC BEPAFCGSDWSTEL-UHFFFAOYSA-N 0.000 abstract 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229930004725 sesquiterpene Natural products 0.000 abstract 1
- 150000004354 sesquiterpene derivatives Chemical class 0.000 abstract 1
- 150000004756 silanes Chemical class 0.000 abstract 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 abstract 1
- KXCAEQNNTZANTK-UHFFFAOYSA-N stannane Chemical compound [SnH4] KXCAEQNNTZANTK-UHFFFAOYSA-N 0.000 abstract 1
- 229910000080 stannane Inorganic materials 0.000 abstract 1
Abstract
NEW MATERIAL:An allylcarboxylic acid derivative shown by the formula I (X is Si or Sn; R1, R2, and R3 are alkyl, aryl, or aralkyl; R4 is hydroxy, alkoxy, or allyloxy, etc.).
EXAMPLE: 2-Ethoxycarbonylallyltrimethyl stannane.
USE: Useful as a reagent for introducing 2-alkoxycarbonylallyl group around an electrophilically center. Useful as an intermediate for synthesizing α-methylene-γ- butyrolactone which is important in synthesizing a natural sesquiterpene or its analog compound having cytotoxin.
PROCESS: In ethanol, dimethyl malonate is reacted with sodium ethoxide to give a reaction product, which is reacted with a halomethylsilane derivative shown by the formula II (Z is halogen) to give a compound shown by the formula III. The compound shown by the formula III is reacted with NaH, and dibromomethane, to give a silane derivative shown by the formula IV, which is treated with KOH in water-ethanol, to give the titled compound shown by the formula V.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1417080A JPS56110693A (en) | 1980-02-07 | 1980-02-07 | Allylcarboxylic acid derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1417080A JPS56110693A (en) | 1980-02-07 | 1980-02-07 | Allylcarboxylic acid derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56110693A true JPS56110693A (en) | 1981-09-01 |
| JPS6337795B2 JPS6337795B2 (en) | 1988-07-27 |
Family
ID=11853659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1417080A Granted JPS56110693A (en) | 1980-02-07 | 1980-02-07 | Allylcarboxylic acid derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56110693A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7192684B2 (en) * | 2002-09-30 | 2007-03-20 | Shin-Etsu Chemical Co., Ltd. | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process |
-
1980
- 1980-02-07 JP JP1417080A patent/JPS56110693A/en active Granted
Non-Patent Citations (1)
| Title |
|---|
| J.ORGANOMET CHEM * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7192684B2 (en) * | 2002-09-30 | 2007-03-20 | Shin-Etsu Chemical Co., Ltd. | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6337795B2 (en) | 1988-07-27 |
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