ES8504139A1 - Procedimiento para preparar derivados de bencimidazol. - Google Patents

Procedimiento para preparar derivados de bencimidazol.

Info

Publication number
ES8504139A1
ES8504139A1 ES521460A ES521460A ES8504139A1 ES 8504139 A1 ES8504139 A1 ES 8504139A1 ES 521460 A ES521460 A ES 521460A ES 521460 A ES521460 A ES 521460A ES 8504139 A1 ES8504139 A1 ES 8504139A1
Authority
ES
Spain
Prior art keywords
benzimidazole derivatives
hydrocarbon moiety
group
arthritis
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521460A
Other languages
English (en)
Other versions
ES521460A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of ES521460A0 publication Critical patent/ES521460A0/es
Publication of ES8504139A1 publication Critical patent/ES8504139A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE BENCIMIDAZOL, DE FORMULA GENERAL (I), EN LA QUE R REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO NITRO O UN HIDROCARBURO; Y R REPRESENTA UN GRUPO ALQUILO DE CADENA RECTA O RAMIFICADA QUE CONTIENE DE 1 A 8 ATOMOS DE CARBONO, O UN ATOMO DE HALOGENO.CONSISTE EN OXIDAR UN COMPUESTO DE FORMULA GENERAL (II) O UNA SAL DEL MISMO, CON UNA SOLUCION DE TRIOXIDO DE CROMO, ACIDO SULFURICO Y AGUA, PREFERIBLEMENTE EN PRESENCIA DE ACETONA.DE APLICACION EN TERAPEUTICA, EN PARTICULAR EN EL TRATAMIENTO DE DESORDENES ARTRITICOS, TALES COMO LA ARTRITIS REUMATOIDE.
ES521460A 1982-04-15 1983-04-14 Procedimiento para preparar derivados de bencimidazol. Expired ES8504139A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8210927 1982-04-15

Publications (2)

Publication Number Publication Date
ES521460A0 ES521460A0 (es) 1985-04-01
ES8504139A1 true ES8504139A1 (es) 1985-04-01

Family

ID=10529707

Family Applications (2)

Application Number Title Priority Date Filing Date
ES521460A Expired ES8504139A1 (es) 1982-04-15 1983-04-14 Procedimiento para preparar derivados de bencimidazol.
ES523937A Expired ES8500909A1 (es) 1982-04-15 1983-07-07 Procedimiento para preparar derivados de bencimidazol

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES523937A Expired ES8500909A1 (es) 1982-04-15 1983-07-07 Procedimiento para preparar derivados de bencimidazol

Country Status (18)

Country Link
JP (1) JPS58188865A (es)
KR (1) KR840004407A (es)
AT (1) ATA135183A (es)
AU (1) AU1350883A (es)
BE (1) BE896465A (es)
DE (1) DE3313599A1 (es)
DK (1) DK164283A (es)
ES (2) ES8504139A1 (es)
FI (1) FI831258L (es)
FR (1) FR2525218A1 (es)
GB (1) GB2119790A (es)
GR (1) GR78209B (es)
IL (1) IL68405A0 (es)
IT (1) IT1164173B (es)
LU (1) LU84747A1 (es)
NL (1) NL8301310A (es)
SE (1) SE8302084L (es)
ZA (1) ZA832638B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2617478B1 (fr) * 1987-07-01 1990-01-05 Esteve Labor Dr Nouveaux derives d'aryl-heteroaryl cetones, leur procede de preparation ainsi que leur application a titre de medicament
US6288100B1 (en) * 1995-06-06 2001-09-11 American Home Products Corporation Benzimidazole derivatives
FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH528514A (de) * 1969-05-22 1972-09-30 Bayer Ag Verfahren zur Herstellung von Acylimidazolen
FR2257269B1 (es) * 1973-10-03 1978-12-29 Delalande Sa

Also Published As

Publication number Publication date
FR2525218A1 (fr) 1983-10-21
ES523937A0 (es) 1984-11-01
GB2119790A (en) 1983-11-23
KR840004407A (ko) 1984-10-15
IT8320578A0 (it) 1983-04-14
ES521460A0 (es) 1985-04-01
DK164283D0 (da) 1983-04-14
IL68405A0 (en) 1983-07-31
ZA832638B (en) 1983-12-28
ES8500909A1 (es) 1984-11-01
DK164283A (da) 1983-10-16
BE896465A (fr) 1983-10-14
FI831258L (fi) 1983-10-16
SE8302084D0 (sv) 1983-04-14
ATA135183A (de) 1985-05-15
SE8302084L (sv) 1983-10-16
GR78209B (es) 1984-09-26
NL8301310A (nl) 1983-11-01
JPS58188865A (ja) 1983-11-04
IT1164173B (it) 1987-04-08
DE3313599A1 (de) 1983-10-20
LU84747A1 (fr) 1983-12-05
AU1350883A (en) 1983-10-20
GB8310146D0 (en) 1983-05-18
FI831258A0 (fi) 1983-04-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040916