ES455741A1 - Un procedimiento para la preparacion de nuevos derivados de 1,3-bencenodimetanol. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de 1,3-bencenodimetanol.Info
- Publication number
- ES455741A1 ES455741A1 ES455741A ES455741A ES455741A1 ES 455741 A1 ES455741 A1 ES 455741A1 ES 455741 A ES455741 A ES 455741A ES 455741 A ES455741 A ES 455741A ES 455741 A1 ES455741 A1 ES 455741A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- straight
- image
- branched chain
- chain alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 3,4-methylenedioxy group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para la preparación de nuevos derivados de 1,3-bencenodimetanol, útiles como estimulantes de los Beta{sub,2}-adrenorreceptores de fórmula: **(Fórmula)** donde R{sup,1} representa hidrógeno, un grupo alquilo de cadena lineal o ramificada o un grupo acilo de fórmula-COR{sup,5} donde R{sup,5} representa un átomo de hidrógeno o un grupo alquilo de cadena lineal o ramificada, R{sup,2}representa un grupo arilo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4929/76A GB1551260A (en) | 1976-02-09 | 1976-02-09 | Phenylethanolamine derivatives |
GB3518276 | 1976-08-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES455741A1 true ES455741A1 (es) | 1978-04-16 |
Family
ID=26239472
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES455741A Expired ES455741A1 (es) | 1976-02-09 | 1977-02-08 | Un procedimiento para la preparacion de nuevos derivados de 1,3-bencenodimetanol. |
ES467069A Expired ES467069A1 (es) | 1976-02-09 | 1978-02-16 | Un procedimiento para la preparacion de nuevos derivados de 1-3-bencenodimetanol |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES467069A Expired ES467069A1 (es) | 1976-02-09 | 1978-02-16 | Un procedimiento para la preparacion de nuevos derivados de 1-3-bencenodimetanol |
Country Status (10)
Country | Link |
---|---|
US (1) | US4154761A (es) |
JP (1) | JPS5297926A (es) |
AU (1) | AU509065B2 (es) |
CH (1) | CH630603A5 (es) |
DE (1) | DE2704895A1 (es) |
DK (1) | DK148444C (es) |
ES (2) | ES455741A1 (es) |
FR (1) | FR2362114A1 (es) |
NL (1) | NL7701304A (es) |
SE (1) | SE440348B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4163053A (en) * | 1977-12-27 | 1979-07-31 | Schering Corporation | Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides |
EP0006298B1 (en) * | 1978-06-15 | 1982-03-31 | Imperial Chemical Industries Plc | Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture |
US4304790A (en) * | 1979-06-12 | 1981-12-08 | Schering Corporation | 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof |
ZW6584A1 (en) * | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
NZ211822A (en) * | 1984-04-17 | 1988-11-29 | Glaxo Group Ltd | Phenethanolamine derivatives and pharmaceutical compositions |
DE3428526A1 (de) * | 1984-08-02 | 1986-02-13 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue aminoalkohole, verfahren zu deren herstellung sowie diese verbindung enthaltende arzneimittel |
US5011993A (en) * | 1986-09-05 | 1991-04-30 | Schering Corporation | Method for the preparation of α1 [[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol |
US4952729A (en) * | 1986-09-05 | 1990-08-28 | Schering-Plough Corp. | Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol |
WO1995033724A1 (en) * | 1994-06-09 | 1995-12-14 | Glaxo Group Limited | Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists |
GB9525121D0 (en) * | 1995-12-08 | 1996-02-07 | Glaxo Group Ltd | Chemical compounds |
GB9525177D0 (en) * | 1995-12-08 | 1996-02-07 | Glaxo Group Ltd | Chemical compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT334335B (de) * | 1973-03-01 | 1976-01-10 | Basf Ag | Verfahren zur herstellung von 1-phenyl-2-aminoathanolen-(1) |
AT219581B (de) * | 1959-06-26 | 1962-02-12 | Donau Pharmazie Gmbh | Verfahren zur Herstellung von neuen Anilinen |
DE1618005A1 (de) * | 1966-09-22 | 1971-09-09 | Thomae Gmbh Dr K | Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen |
GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
GB1301134A (en) * | 1970-07-18 | 1972-12-29 | Pfizer Ltd | SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES |
AT310146B (de) * | 1971-04-26 | 1973-09-25 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von neuen N,N'-Bis-(β-hydroxyaryläthyl)-diaminoalkanen und deren Säureadditionssalzen |
US3879442A (en) * | 1972-07-27 | 1975-04-22 | Warner Lambert Co | 5-hydroxy-{60 (substituted aminomethyl)-mu-xylene-{60 ,{60 -diols |
-
1977
- 1977-01-28 US US05/763,618 patent/US4154761A/en not_active Expired - Lifetime
- 1977-02-05 DE DE19772704895 patent/DE2704895A1/de not_active Ceased
- 1977-02-08 DK DK52977A patent/DK148444C/da not_active IP Right Cessation
- 1977-02-08 ES ES455741A patent/ES455741A1/es not_active Expired
- 1977-02-08 NL NL7701304A patent/NL7701304A/xx not_active Application Discontinuation
- 1977-02-08 SE SE7701379A patent/SE440348B/xx unknown
- 1977-02-09 CH CH174877A patent/CH630603A5/de not_active IP Right Cessation
- 1977-02-09 JP JP1346877A patent/JPS5297926A/ja active Pending
- 1977-02-09 FR FR7703611A patent/FR2362114A1/fr active Granted
- 1977-02-09 AU AU22133/77A patent/AU509065B2/en not_active Expired
-
1978
- 1978-02-16 ES ES467069A patent/ES467069A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU2213377A (en) | 1978-08-17 |
JPS5297926A (en) | 1977-08-17 |
DE2704895A1 (de) | 1977-08-11 |
DK148444B (da) | 1985-07-08 |
FR2362114A1 (fr) | 1978-03-17 |
CH630603A5 (de) | 1982-06-30 |
NL7701304A (nl) | 1977-08-11 |
FR2362114B1 (es) | 1979-03-09 |
AU509065B2 (en) | 1980-04-17 |
US4154761A (en) | 1979-05-15 |
DK52977A (da) | 1977-08-10 |
SE440348B (sv) | 1985-07-29 |
DK148444C (da) | 1985-12-09 |
SE7701379L (sv) | 1977-08-10 |
ES467069A1 (es) | 1979-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980202 |