GB2004885A - Indolopyrones - Google Patents
IndolopyronesInfo
- Publication number
- GB2004885A GB2004885A GB7838490A GB7838490A GB2004885A GB 2004885 A GB2004885 A GB 2004885A GB 7838490 A GB7838490 A GB 7838490A GB 7838490 A GB7838490 A GB 7838490A GB 2004885 A GB2004885 A GB 2004885A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- carbon atoms
- alkyl
- present
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The present invention provides compounds of the general formula:- <IMAGE> wherein R1 and R2, which may be the same or different, are hydrogen or halogen atoms, hydroxy or nitro groups, alkyl or alkoxy radicals containing up to 6 carbon atoms or trifluoromethyl radicals or R1 and R2 together represent a methylenedioxy radical, R3 is a hydrogen atom, an alkyl radical containing up to 6 carbon atoms or an aryl or substituted aryl radical and R4 is a carboxamido, cyano or tetrazolyl radical; and the pharmaceutically acceptable organic and inorganic salts thereof. The present invention also provides a process for preparing these compounds, as well as pharmaceutical compositions containing them.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83820077A | 1977-09-30 | 1977-09-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2004885A true GB2004885A (en) | 1979-04-11 |
GB2004885B GB2004885B (en) | 1982-03-24 |
Family
ID=25276532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7838490A Expired GB2004885B (en) | 1977-09-30 | 1978-09-28 | Indolopyrones process for the preparation thereof and pharmaceutical compositions containing them |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5470300A (en) |
AU (1) | AU522053B2 (en) |
CA (1) | CA1110249A (en) |
DE (1) | DE2837236A1 (en) |
DK (1) | DK432778A (en) |
FR (1) | FR2404640A1 (en) |
GB (1) | GB2004885B (en) |
IT (1) | IT1107244B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0092380A2 (en) * | 1982-04-19 | 1983-10-26 | Warner-Lambert Company | Antiallergic 4H-furo(3,2-b)indoles and their production |
US4596814A (en) * | 1983-01-10 | 1986-06-24 | Warner-Lambert Company | Tetrazolyl- and carboxamidotetrazolyl-substituted 4H-furo[3,2-b] indoles and anti-allergic use thereof |
CN114702504A (en) * | 2022-01-29 | 2022-07-05 | 平顶山学院 | Trifluoromethyl substituted indolopyranone compound, preparation method thereof and application thereof in antitumor drugs |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009063780A1 (en) * | 2007-11-12 | 2009-05-22 | Mitsui Chemicals, Inc. | Organic transistor |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4028383A (en) * | 1975-09-08 | 1977-06-07 | Warner-Lambert Company | Indolopyrones having antiallergic activity |
-
1978
- 1978-08-25 DE DE19782837236 patent/DE2837236A1/en not_active Ceased
- 1978-09-12 FR FR7826102A patent/FR2404640A1/en active Granted
- 1978-09-27 IT IT51273/78A patent/IT1107244B/en active
- 1978-09-28 GB GB7838490A patent/GB2004885B/en not_active Expired
- 1978-09-28 AU AU40288/78A patent/AU522053B2/en not_active Expired
- 1978-09-29 CA CA312,357A patent/CA1110249A/en not_active Expired
- 1978-09-29 DK DK432778A patent/DK432778A/en not_active Application Discontinuation
- 1978-09-29 JP JP11939878A patent/JPS5470300A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0092380A2 (en) * | 1982-04-19 | 1983-10-26 | Warner-Lambert Company | Antiallergic 4H-furo(3,2-b)indoles and their production |
EP0092380A3 (en) * | 1982-04-19 | 1984-05-30 | Warner-Lambert Company | Antiallergic 4h-furo(3,2-b)indoles and their production |
US4596814A (en) * | 1983-01-10 | 1986-06-24 | Warner-Lambert Company | Tetrazolyl- and carboxamidotetrazolyl-substituted 4H-furo[3,2-b] indoles and anti-allergic use thereof |
CN114702504A (en) * | 2022-01-29 | 2022-07-05 | 平顶山学院 | Trifluoromethyl substituted indolopyranone compound, preparation method thereof and application thereof in antitumor drugs |
CN114702504B (en) * | 2022-01-29 | 2023-04-07 | 平顶山学院 | Trifluoromethyl substituted indolopyranone compound, preparation method thereof and application thereof in antitumor drugs |
Also Published As
Publication number | Publication date |
---|---|
FR2404640A1 (en) | 1979-04-27 |
FR2404640B1 (en) | 1981-07-24 |
AU4028878A (en) | 1980-04-03 |
IT7851273A0 (en) | 1978-09-27 |
DK432778A (en) | 1979-03-31 |
IT1107244B (en) | 1985-11-25 |
GB2004885B (en) | 1982-03-24 |
CA1110249A (en) | 1981-10-06 |
JPS5470300A (en) | 1979-06-05 |
DE2837236A1 (en) | 1979-04-05 |
AU522053B2 (en) | 1982-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |