JPS57171973A - Manufacture of 4-amino-chloroquinolines - Google Patents

Manufacture of 4-amino-chloroquinolines

Info

Publication number
JPS57171973A
JPS57171973A JP57003535A JP353582A JPS57171973A JP S57171973 A JPS57171973 A JP S57171973A JP 57003535 A JP57003535 A JP 57003535A JP 353582 A JP353582 A JP 353582A JP S57171973 A JPS57171973 A JP S57171973A
Authority
JP
Japan
Prior art keywords
amino
formula
image
optionally substituted
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57003535A
Other languages
English (en)
Inventor
Bodouan Mishieru
Mishiyure Danieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROONNPUURAN SANTO
Rhone Poulenc Sante SA
Original Assignee
ROONNPUURAN SANTO
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROONNPUURAN SANTO, Rhone Poulenc Sante SA filed Critical ROONNPUURAN SANTO
Publication of JPS57171973A publication Critical patent/JPS57171973A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP57003535A 1981-01-16 1982-01-14 Manufacture of 4-amino-chloroquinolines Pending JPS57171973A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8100765A FR2498187A1 (fr) 1981-01-16 1981-01-16 Procede de preparation d'amino-4 chloro-7 quinoleines

Publications (1)

Publication Number Publication Date
JPS57171973A true JPS57171973A (en) 1982-10-22

Family

ID=9254223

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57003535A Pending JPS57171973A (en) 1981-01-16 1982-01-14 Manufacture of 4-amino-chloroquinolines

Country Status (13)

Country Link
US (1) US4421920A (ja)
EP (1) EP0056766B1 (ja)
JP (1) JPS57171973A (ja)
KR (1) KR870001921B1 (ja)
AT (1) ATE7492T1 (ja)
CA (1) CA1171861A (ja)
DE (1) DE3260150D1 (ja)
DK (1) DK148805C (ja)
FR (1) FR2498187A1 (ja)
HU (1) HU184985B (ja)
IE (1) IE51957B1 (ja)
IN (1) IN158327B (ja)
ZA (1) ZA82277B (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007124A1 (en) * 1991-09-30 1993-04-15 Eisai Co., Ltd. Nitrogenous heterocyclic compound
JPH07188174A (ja) * 1993-10-28 1995-07-25 F Hoffmann La Roche Ag アミノキノリン誘導体
JP2007517837A (ja) * 2004-01-14 2007-07-05 コンセホ・スペリオール・デ・インベスティガシオネス・シエンティフィカス ピリジニウムおよびキノリニウム誘導体

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2892298A (en) * 1957-08-05 1959-06-30 Earl J Chaney Pickup device
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
EP0222839A4 (en) * 1985-05-17 1988-11-09 Univ Australian ANTI-MALARIA COMPOUNDS.
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
CA1340821C (en) * 1988-10-06 1999-11-16 Nobuyuki Fukazawa Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
WO1996040138A1 (en) * 1995-06-07 1996-12-19 The Administrators Of The Tulane Educational Fund Chloroquine analogs and methods of preventing and treating plasmodial disease
IL125954A (en) 1996-03-05 2003-06-24 Zeneca Ltd Quinazoline derivatives, processes for their preparation, pharmaceutical compositions containing them and use thereof in the manufacture of medicaments having an antiangiogenic and/or vascular permeability reducing effect
US6809097B1 (en) * 1996-09-25 2004-10-26 Zeneca Limited Quinoline derivatives inhibiting the effect of growth factors such as VEGF
GB9910579D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910580D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
WO2001003649A2 (en) 1999-07-13 2001-01-18 Alpha Research Group, Llc Compositions and methods for the treatment of parkinson's disease
US20040229908A1 (en) * 1999-07-13 2004-11-18 Jodi Nelson Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias
BR0109828A (pt) * 2000-04-07 2002-12-17 Astrazeneca Ab Composto, processo para a prepapação do mesmo ou de um sal deste, composição farmacêutica, uso do composto ou de um sal deste farmaceuticamente aceitável, e, método para a produção de um efeito antiangiogênico e/ou redutor da permeabilidade vascular em um animal de sangue quente em necessidade de tal tratamento
US7067532B2 (en) * 2000-11-02 2006-06-27 Astrazeneca Substituted quinolines as antitumor agents
US7253184B2 (en) * 2000-11-02 2007-08-07 Astrazeneca Ab 4-Substituted quinolines as antitumor agents
US7084157B2 (en) * 2002-05-17 2006-08-01 Rajeev Raut Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation
US20040002451A1 (en) * 2002-06-20 2004-01-01 Bruce Kerwin Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
GB0215823D0 (en) * 2002-07-09 2002-08-14 Astrazeneca Ab Quinazoline derivatives
GB0225579D0 (en) * 2002-11-02 2002-12-11 Astrazeneca Ab Chemical compounds
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US7108992B2 (en) * 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
US7618975B2 (en) 2003-07-03 2009-11-17 Myriad Pharmaceuticals, Inc. 4-arylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
UA82577C2 (en) * 2003-12-23 2008-04-25 Пфайзер Инк. Quinoline derivatives
US8586613B2 (en) 2004-01-14 2013-11-19 Universidad De Granada Pyridinium and quinolinium derivatives
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
CA2592900A1 (en) 2005-01-03 2006-07-13 Myriad Genetics Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
WO2007059372A2 (en) * 2005-11-09 2007-05-24 St. Jude Children's Research Hospital Use of chloroquine to treat metabolic syndrome
CN105693606B (zh) * 2016-03-09 2017-12-05 西安科技大学 一种光学纯(r)/(s)‑羟氯喹的不对称合成方法
CN105693605B (zh) * 2016-03-09 2017-12-22 西安科技大学 一种光学纯(r)/(s)‑氯喹的不对称合成方法
WO2022112596A1 (en) 2020-11-30 2022-06-02 Cellectis Sa Use of aminoquinoline compounds for higher gene integration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653940A (en) * 1951-01-27 1953-09-29 William S Johnson Process for preparing 4-quinolyl secondary amines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007124A1 (en) * 1991-09-30 1993-04-15 Eisai Co., Ltd. Nitrogenous heterocyclic compound
JPH07188174A (ja) * 1993-10-28 1995-07-25 F Hoffmann La Roche Ag アミノキノリン誘導体
JP2007517837A (ja) * 2004-01-14 2007-07-05 コンセホ・スペリオール・デ・インベスティガシオネス・シエンティフィカス ピリジニウムおよびキノリニウム誘導体

Also Published As

Publication number Publication date
ZA82277B (en) 1982-11-24
DK148805B (da) 1985-10-07
US4421920A (en) 1983-12-20
DK148805C (da) 1986-04-01
FR2498187A1 (fr) 1982-07-23
EP0056766B1 (fr) 1984-05-16
KR870001921B1 (ko) 1987-10-22
CA1171861A (fr) 1984-07-31
KR830009038A (ko) 1983-12-17
IE820075L (en) 1982-07-16
ATE7492T1 (de) 1984-06-15
HU184985B (en) 1984-11-28
IN158327B (ja) 1986-10-18
DK16582A (da) 1982-07-17
DE3260150D1 (en) 1984-06-20
EP0056766A1 (fr) 1982-07-28
IE51957B1 (en) 1987-04-29
FR2498187B1 (ja) 1983-09-30

Similar Documents

Publication Publication Date Title
JPS57171973A (en) Manufacture of 4-amino-chloroquinolines
ES8402173A1 (es) Un metodo para la preparacion de una catalizador de quelato de titanio.
GR79637B (ja)
GB2185252B (en) Triazole derivatives
ZA858169B (en) New adamantanamine derivatives,processes for their preparation and drugs in which they are present
ES8703458A1 (es) Un procedimiento para preparar acido 7b-(metiltio fluorado)acetamide-7x-metaxi-3--1-(2-hidroxialquil)-ih-tetrazol-5-il- tiometil-1-destia-1-oxa-3-cefem-4-carboxilico.
IE822391L (en) 4-acylamino-1-azaadamantanes
ES480429A1 (es) Un procedimiento para la preparacion de derivados de 1,5-di-metilbiciclo(3.2.1.)octano.
ES8204716A1 (es) Un procedimiento de preparacion de derivados bencilidenicos
ATE87307T1 (de) Isoindolinderivate und verfahren zu ihrer herstellung.
EP0074497A3 (en) Process for the preparation of 3-alkyl-6-methyl-beta-resorcylic-acid esters
ES8500909A1 (es) Procedimiento para preparar derivados de bencimidazol
IL65666A (en) Derivatives of 4-aminomethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones and process for their preparation
IL65667A (en) 4-(4-phenyl-1-piperidinyl)methyl-5-benzoyl-1,3-dihydro-2h-imidazol-2-one derivatives and process for their preparation
DE3160549D1 (en) Process for the preparation of chlorophenols
ES8101560A1 (es) Procedimiento para la preparacion de bencimidazol-carbamatos
ES8305333A1 (es) "procedimiento para la preparacion de nuevas sulfiminas".