FI870842A - Foerfarande foer framstaellning av nya derivat av 1,2,5,6-tetrahydropyridin-3-karboxialdehydoxim. - Google Patents

Foerfarande foer framstaellning av nya derivat av 1,2,5,6-tetrahydropyridin-3-karboxialdehydoxim. Download PDF

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Publication number
FI870842A
FI870842A FI870842A FI870842A FI870842A FI 870842 A FI870842 A FI 870842A FI 870842 A FI870842 A FI 870842A FI 870842 A FI870842 A FI 870842A FI 870842 A FI870842 A FI 870842A
Authority
FI
Finland
Prior art keywords
radical
carbon atoms
karboxialdehydoxim
derivat
nya
Prior art date
Application number
FI870842A
Other languages
English (en)
Other versions
FI87199B (fi
FI870842A0 (fi
FI87199C (fi
Inventor
Giulio Galliani
Fernando Barzaghi
Alina Butti
Carla Bonetti
Emilio Toja
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT19565/86A external-priority patent/IT1191667B/it
Priority claimed from IT21157/86A external-priority patent/IT1196510B/it
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI870842A0 publication Critical patent/FI870842A0/fi
Publication of FI870842A publication Critical patent/FI870842A/fi
Publication of FI87199B publication Critical patent/FI87199B/fi
Application granted granted Critical
Publication of FI87199C publication Critical patent/FI87199C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI870842A 1986-02-27 1987-02-26 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,2,5,6-tetrahydropyridin-3-karboxialdoximderivat FI87199C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT19565/86A IT1191667B (it) 1986-02-27 1986-02-27 Derivati della 1,2,5,6-tetraidropiridin-3-carbossaldeide ossima,loro procedimento di preparazione e loro applicazione come farmaci
IT1956586 1986-02-27
IT2115786 1986-07-17
IT21157/86A IT1196510B (it) 1986-07-17 1986-07-17 Derivati della 1,2-5,6-tetraidropiridin-3-carbossaldeide ossima,loro procedimento di preparazione e loro applicazione come farmaci

Publications (4)

Publication Number Publication Date
FI870842A0 FI870842A0 (fi) 1987-02-26
FI870842A true FI870842A (fi) 1987-08-28
FI87199B FI87199B (fi) 1992-08-31
FI87199C FI87199C (fi) 1992-12-10

Family

ID=26327212

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870842A FI87199C (fi) 1986-02-27 1987-02-26 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,2,5,6-tetrahydropyridin-3-karboxialdoximderivat

Country Status (20)

Country Link
US (3) US5219872A (fi)
EP (1) EP0239445B1 (fi)
JP (1) JPH07599B2 (fi)
KR (1) KR950005197B1 (fi)
AT (1) ATE76066T1 (fi)
AU (1) AU588972B2 (fi)
BG (1) BG61120B2 (fi)
CA (1) CA1327803C (fi)
DE (1) DE3778951D1 (fi)
DK (1) DK167803B1 (fi)
ES (1) ES2032456T3 (fi)
FI (1) FI87199C (fi)
GR (1) GR3004845T3 (fi)
HK (1) HK29797A (fi)
HU (1) HU198018B (fi)
IE (1) IE59095B1 (fi)
IL (1) IL81610A (fi)
NO (1) NO172180C (fi)
NZ (1) NZ219416A (fi)
PT (1) PT84366B (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
IT1233446B (it) * 1987-12-30 1992-04-01 Roussel Maestretti Spa Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci
EP0338723B1 (en) * 1988-04-15 1993-08-04 Beecham Group Plc Novel compounds
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
DE69034146T2 (de) * 1989-04-13 2005-07-14 Beecham Group P.L.C., Brentford Chemische Verbindungen
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
WO1992003435A1 (en) * 1990-08-24 1992-03-05 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
US5356914A (en) * 1990-10-12 1994-10-18 Beecham Group P.L.C. 1,2,5,6-tetrahydropyridine oxime derivatives
AU3142793A (en) * 1991-12-18 1993-07-19 Warner-Lambert Company Transdermal delivery of (E)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-O- methyloxine HCL and related compounds in the treatment of cognitive disorders and for analgesia
AU5297693A (en) * 1992-10-06 1994-04-26 Warner-Lambert Company Stabilized compositions containing 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxyaldehyde-o-meth yl-oxime
ZA937382B (en) * 1992-10-06 1994-04-29 Warner Lambert Co Novel composition for peroral therapy of cognitionimpairment and a process therefor
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5731314A (en) * 1995-01-06 1998-03-24 Bencherif; Merouane Pharamceutical compositions for prevention and treatment of tourette's syndrome
US5583140A (en) * 1995-05-17 1996-12-10 Bencherif; Merouane Pharmaceutical compositions for the treatment of central nervous system disorders
DE19707655A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Kombinationspräparat zur Anwendung bei Demenz
US6455648B1 (en) 1999-12-29 2002-09-24 Chevron Phillips Chemical Company Lp Olefin production
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
US9877500B2 (en) * 2007-03-14 2018-01-30 Concentrate Manufacturing Company Of Ireland Natural beverage products
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CH704993A1 (fr) 2011-05-20 2012-11-30 Bacab S A Câble électrique.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Also Published As

Publication number Publication date
IL81610A0 (en) 1987-09-16
FI87199B (fi) 1992-08-31
FI870842A0 (fi) 1987-02-26
DK98787D0 (da) 1987-02-26
PT84366B (pt) 1989-10-04
DK98787A (da) 1987-08-28
FI87199C (fi) 1992-12-10
JPH07599B2 (ja) 1995-01-11
GR3004845T3 (fi) 1993-04-28
PT84366A (en) 1987-03-01
US5532375A (en) 1996-07-02
NO870771D0 (no) 1987-02-25
KR870007890A (ko) 1987-09-22
IL81610A (en) 1990-12-23
HUT44497A (en) 1988-03-28
EP0239445A2 (fr) 1987-09-30
HK29797A (en) 1997-03-21
NO870771L (no) 1987-08-28
KR950005197B1 (ko) 1995-05-19
EP0239445B1 (fr) 1992-05-13
AU588972B2 (en) 1989-09-28
DE3778951D1 (de) 1992-06-17
US5391754A (en) 1995-02-21
IE59095B1 (en) 1994-01-12
ATE76066T1 (de) 1992-05-15
US5219872A (en) 1993-06-15
NO172180C (no) 1993-06-16
EP0239445A3 (en) 1989-01-18
ES2032456T3 (es) 1993-02-16
CA1327803C (en) 1994-03-15
DK167803B1 (da) 1993-12-20
NZ219416A (en) 1989-04-26
IE870497L (en) 1987-08-27
JPS62252767A (ja) 1987-11-04
NO172180B (no) 1993-03-08
BG61120B2 (bg) 1996-11-29
AU6927987A (en) 1987-09-03
HU198018B (en) 1989-07-28

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Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: HOECHST MARION ROUSSEL

MM Patent lapsed

Owner name: AVENTIS PHARMA S.A.