FI850140L - Kemiska foereningar. - Google Patents
Kemiska foereningar.Info
- Publication number
- FI850140L FI850140L FI850140A FI850140A FI850140L FI 850140 L FI850140 L FI 850140L FI 850140 A FI850140 A FI 850140A FI 850140 A FI850140 A FI 850140A FI 850140 L FI850140 L FI 850140L
- Authority
- FI
- Finland
- Prior art keywords
- compounds
- formula
- foereningar
- chemical
- chemical foereningar
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848400863A GB8400863D0 (en) | 1984-01-13 | 1984-01-13 | Chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI850140A0 FI850140A0 (fi) | 1985-01-11 |
| FI850140L true FI850140L (fi) | 1985-07-14 |
Family
ID=10554924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI850140A FI850140L (fi) | 1984-01-13 | 1985-01-11 | Kemiska foereningar. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4654342A (de) |
| EP (1) | EP0150937B1 (de) |
| JP (3) | JPS60158181A (de) |
| KR (1) | KR920006781B1 (de) |
| CN (1) | CN85101722A (de) |
| AT (1) | ATE37179T1 (de) |
| AU (1) | AU572252B2 (de) |
| CA (2) | CA1251209A (de) |
| CS (1) | CS248731B2 (de) |
| DD (1) | DD231350A5 (de) |
| DE (1) | DE3564941D1 (de) |
| DK (1) | DK162519C (de) |
| ES (3) | ES8607949A1 (de) |
| FI (1) | FI850140L (de) |
| GB (1) | GB8400863D0 (de) |
| GR (1) | GR850068B (de) |
| HU (1) | HU193591B (de) |
| IE (1) | IE57969B1 (de) |
| IL (1) | IL74031A (de) |
| JO (1) | JO1351B1 (de) |
| MY (1) | MY100124A (de) |
| NO (1) | NO850129L (de) |
| NZ (1) | NZ210816A (de) |
| PH (1) | PH22136A (de) |
| PL (1) | PL147123B1 (de) |
| PT (1) | PT79819B (de) |
| RO (1) | RO92607A (de) |
| SU (1) | SU1396963A3 (de) |
| WO (1) | WO1985003076A1 (de) |
| ZA (1) | ZA85251B (de) |
| ZW (1) | ZW385A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1251448A (en) * | 1985-03-27 | 1989-03-21 | William J. Coates | Pyridazinone derivatives |
| AU581324B2 (en) * | 1985-07-05 | 1989-02-16 | Smith Kline & French Laboratories Limited | Substituted 6-phenyl-4,5-dihydro pyradazin-3-ones |
| GB8603780D0 (en) * | 1986-02-15 | 1986-03-19 | Smith Kline French Lab | Chemical compounds |
| GB8722776D0 (en) * | 1987-09-28 | 1987-11-04 | Smith Kline French Lab | Chemical compounds |
| US5011837A (en) * | 1988-08-09 | 1991-04-30 | E. R. Squibb & Sons, Inc. | Aryl cyanoguanidines: potassium channel activators and method of making same |
| NZ229828A (en) * | 1988-08-09 | 1992-03-26 | Squibb & Sons Inc | Aryl cyanoguanidine derivatives and pharmaceutical compositions |
| ES2271247T3 (es) * | 2001-02-27 | 2007-04-16 | Migenix Corp. | Aril-n-cianoguanidinas y metodo relacionados con ellas. |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| DE102004011512B4 (de) | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
| EP1579862A1 (de) * | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von PDE III Ihibitoren zur Reduktion der Herzgrösse in an Herzversagen leidenden Säugern |
| US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
| EP2218442A1 (de) | 2005-11-09 | 2010-08-18 | CombinatoRx, Inc. | Verfahren, Zusammensetzungen und Kits zur Behandlung von ophthalmologischen Erkrankungen |
| CA2629367C (en) * | 2005-11-14 | 2016-05-03 | Boehringer Ingelheim Vetmedica Gmbh | Use of pde iii inhibitors and/or calcium sensitizers for the treatment of asymptomatic (occult) heart failure |
| EP1920785A1 (de) * | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Pimobendan-Cyclodextrin Komplex enthaltendes flüssiges Präparat |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| ES2436716T3 (es) | 2008-11-25 | 2014-01-03 | Boehringer Ingelheim Vetmedica Gmbh | Pimobendan para uso en el tratamiento de la cardiomiopatía hipertrófica en gatos |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9580471B2 (en) | 2011-03-01 | 2017-02-28 | Synergy Pharmaceuticals, Inc. | Process of preparing guanylate cyclase C agonists |
| WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| EP3167876B1 (de) | 2012-03-15 | 2021-09-08 | Boehringer Ingelheim Vetmedica GmbH | Pharmazeutische tablettenformulierung für den veterinärmedizinischen sektor, verfahren zur herstellung und verwendung davon |
| US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| EP2970384A1 (de) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonisten der guanylatcyclase und deren verwendungen |
| JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法 |
| CN113181110A (zh) | 2013-07-19 | 2021-07-30 | 勃林格殷格翰动物保健有限公司 | 含有防腐的醚化的环糊精衍生物的液体水性药物组合物 |
| JP6694385B2 (ja) | 2013-08-09 | 2020-05-13 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| BR112016011111B1 (pt) | 2013-12-04 | 2022-11-16 | Boehringer Ingelheim Vetmedica Gmbh | Composições farmacêuticas aprimoradas de pimobendan |
| CN104987310A (zh) * | 2015-06-03 | 2015-10-21 | 青岛农业大学 | 左西孟旦的合成工艺 |
| US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
| CN110117257B (zh) * | 2018-02-05 | 2022-12-06 | 安徽省新星药物开发有限责任公司 | 一种含胍基的p2y12受体拮抗剂、制备方法及其用途 |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822260A (en) * | 1970-10-09 | 1974-07-02 | American Cyanamid Co | 6-(cyanophenyl)-4,5-dihydro-3(2h)-pyridazinones |
| BE791539A (fr) * | 1971-11-19 | 1973-05-17 | Basf Ag | Dihydropyridazones, leur preparation et leurs utilisations therapeutiques |
| DE3063196D1 (en) * | 1979-12-05 | 1983-06-16 | Morishita Pharma | Derivatives of 2-substituted-6-phenyl-3(2h)pyridazinone, their production and pharmaceutical compositions containing them |
| ATE13294T1 (de) * | 1981-03-04 | 1985-06-15 | Ciba Geigy Ag | Pyridazinone, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen und deren verwendung. |
| JPS58113180A (ja) * | 1981-12-28 | 1983-07-05 | Mitsui Toatsu Chem Inc | ピリダジノン誘導体 |
| JPS58140076A (ja) * | 1982-02-09 | 1983-08-19 | Mitsubishi Chem Ind Ltd | ピリダジノン誘導体又はその塩類 |
| DE3204375C2 (de) * | 1982-02-09 | 1983-12-01 | J. Rettenmaier & Söhne GmbH + Co, 7091 Holzmühle | Verfahren zur Herabsetzung der Saugfähigkeit von Holz |
| DE3302021A1 (de) * | 1983-01-22 | 1984-07-26 | Basf Ag, 6700 Ludwigshafen | 6-aryl-4,5-dihydro-3(2h)-pyridazinone, ihre herstellung und verwendung |
| AU581324B2 (en) * | 1985-07-05 | 1989-02-16 | Smith Kline & French Laboratories Limited | Substituted 6-phenyl-4,5-dihydro pyradazin-3-ones |
-
1984
- 1984-01-13 GB GB848400863A patent/GB8400863D0/en active Pending
-
1985
- 1985-01-02 JO JO19851351A patent/JO1351B1/en active
- 1985-01-07 ZW ZW3/85A patent/ZW385A1/xx unknown
- 1985-01-07 CA CA000471594A patent/CA1251209A/en not_active Expired
- 1985-01-08 DK DK009185A patent/DK162519C/da not_active IP Right Cessation
- 1985-01-09 PH PH31697A patent/PH22136A/en unknown
- 1985-01-10 ES ES539446A patent/ES8607949A1/es not_active Expired
- 1985-01-10 DD DD85272500A patent/DD231350A5/de not_active IP Right Cessation
- 1985-01-10 GR GR850068A patent/GR850068B/el unknown
- 1985-01-10 CS CS85202A patent/CS248731B2/cs unknown
- 1985-01-10 IL IL74031A patent/IL74031A/xx unknown
- 1985-01-10 PT PT79819A patent/PT79819B/pt not_active IP Right Cessation
- 1985-01-11 AU AU37611/85A patent/AU572252B2/en not_active Ceased
- 1985-01-11 NZ NZ210816A patent/NZ210816A/en unknown
- 1985-01-11 PL PL1985251516A patent/PL147123B1/pl unknown
- 1985-01-11 JP JP60003912A patent/JPS60158181A/ja active Pending
- 1985-01-11 HU HU85109A patent/HU193591B/hu not_active IP Right Cessation
- 1985-01-11 ZA ZA85251A patent/ZA85251B/xx unknown
- 1985-01-11 EP EP85300196A patent/EP0150937B1/de not_active Expired
- 1985-01-11 DE DE8585300196T patent/DE3564941D1/de not_active Expired
- 1985-01-11 IE IE69/85A patent/IE57969B1/en not_active IP Right Cessation
- 1985-01-11 FI FI850140A patent/FI850140L/fi not_active Application Discontinuation
- 1985-01-11 AT AT85300196T patent/ATE37179T1/de active
- 1985-01-11 NO NO850129A patent/NO850129L/no unknown
- 1985-01-11 WO PCT/GB1985/000014 patent/WO1985003076A1/en unknown
- 1985-01-12 KR KR1019850000179A patent/KR920006781B1/ko not_active IP Right Cessation
- 1985-01-14 US US06/690,911 patent/US4654342A/en not_active Expired - Fee Related
- 1985-04-01 CN CN198585101722A patent/CN85101722A/zh active Pending
- 1985-09-12 RO RO85120090A patent/RO92607A/ro unknown
- 1985-09-12 SU SU853958649A patent/SU1396963A3/ru active
- 1985-12-05 ES ES549629A patent/ES8703846A1/es not_active Expired
-
1986
- 1986-05-14 ES ES554965A patent/ES8706645A1/es not_active Expired
-
1987
- 1987-06-02 MY MYPI87000758A patent/MY100124A/en unknown
-
1988
- 1988-05-09 JP JP63113411A patent/JPS63313776A/ja active Pending
- 1988-05-09 JP JP63113410A patent/JPS63313775A/ja active Pending
- 1988-10-21 CA CA000581012A patent/CA1260471A/en not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI850140L (fi) | Kemiska foereningar. | |
| ZA811585B (en) | Anti-inflammatory compositions | |
| DE3772850D1 (de) | Thiadiazinon-derivate. | |
| DK316986A (da) | Kemiske forbindelser, som er phosphodiesterase type iii inhibitorer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: SMITH KLINE & FRENCH LABORATORIES |