FI843111A0 - Foerfarande foer framstaellning av penemer. - Google Patents

Foerfarande foer framstaellning av penemer.

Info

Publication number
FI843111A0
FI843111A0 FI843111A FI843111A FI843111A0 FI 843111 A0 FI843111 A0 FI 843111A0 FI 843111 A FI843111 A FI 843111A FI 843111 A FI843111 A FI 843111A FI 843111 A0 FI843111 A0 FI 843111A0
Authority
FI
Finland
Prior art keywords
penemer
foerfarande foer
foer framstaellning
framstaellning
foerfarande
Prior art date
Application number
FI843111A
Other languages
English (en)
Other versions
FI83521B (fi
FI83521C (fi
FI843111A (fi
Inventor
Carlo Battistini
Maurizio Foglio
Giovanni Franceschi
Cosimo Scarafile
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI843111A0 publication Critical patent/FI843111A0/fi
Publication of FI843111A publication Critical patent/FI843111A/fi
Publication of FI83521B publication Critical patent/FI83521B/fi
Application granted granted Critical
Publication of FI83521C publication Critical patent/FI83521C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/06—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI843111A 1983-08-11 1984-08-08 Foerfarande foer framstaellning av penemer. FI83521C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838321677A GB8321677D0 (en) 1983-08-11 1983-08-11 Preparation of penems
GB8321677 1983-08-11

Publications (4)

Publication Number Publication Date
FI843111A0 true FI843111A0 (fi) 1984-08-08
FI843111A FI843111A (fi) 1985-02-12
FI83521B FI83521B (fi) 1991-04-15
FI83521C FI83521C (fi) 1991-07-25

Family

ID=10547172

Family Applications (1)

Application Number Title Priority Date Filing Date
FI843111A FI83521C (fi) 1983-08-11 1984-08-08 Foerfarande foer framstaellning av penemer.

Country Status (20)

Country Link
US (1) US4631150A (fi)
JP (1) JPS6058988A (fi)
KR (1) KR910002098B1 (fi)
AT (1) AT383808B (fi)
BE (1) BE900316A (fi)
CA (1) CA1279640C (fi)
CH (1) CH663024A5 (fi)
DE (1) DE3429102A1 (fi)
DK (1) DK167926B1 (fi)
ES (1) ES534892A0 (fi)
FI (1) FI83521C (fi)
FR (1) FR2550533B1 (fi)
GB (2) GB8321677D0 (fi)
GR (1) GR80102B (fi)
HU (1) HU192415B (fi)
IL (1) IL72612A (fi)
IT (1) IT1209578B (fi)
NL (1) NL8402478A (fi)
PT (1) PT79065B (fi)
SE (1) SE463514B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8416651D0 (en) * 1984-06-29 1984-08-01 Erba Farmitalia Penem derivatives
DE3688960D1 (de) * 1985-09-11 1993-10-07 Ciba Geigy Synthese von Beta-Lactamverbindungen.
US5215997A (en) * 1985-09-11 1993-06-01 Ciba-Geigy Corporation Synthesis of beta-lactam compounds
EP0232966B1 (en) * 1986-01-17 1997-10-08 Beecham Group Plc Process for the preparation of penem compounds and intermediates for this preparation
EP0233155A1 (de) * 1986-02-14 1987-08-19 Ciba-Geigy Ag Aminoacyloxymethyl-Verbindungen
US5215891A (en) * 1986-10-15 1993-06-01 Farmitalia Carlo Erba Process for preparing penems
EP0279781A3 (de) * 1987-02-17 1989-07-26 Ciba-Geigy Ag Verfahren zur Herstellung von 4-Acetoxy-3-hydroxyethyl-azetidinon
US5312914A (en) * 1987-02-17 1994-05-17 Ciba-Geigy Corp Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone
GB8713515D0 (en) * 1987-06-10 1987-07-15 Erba Farmitalia Methoxymethyl compounds
US5364768A (en) * 1987-07-07 1994-11-15 Farmitalia Carlo Erba S.R.L. Process for the preparation of penems
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
US4992543A (en) * 1988-10-19 1991-02-12 Pfizer Inc. Penem derivatives
US5191075A (en) * 1988-10-19 1993-03-02 Pfizer Inc Process for the preparation of penems
US5273973A (en) * 1988-10-24 1993-12-28 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl esters
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
CA2001203C (en) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Novel antimicrobial dithiocarbamoyl quinolones
US5198544A (en) * 1989-04-29 1993-03-30 Hoechst Aktiengesellschaft Process for the preparation of penem compounds
EP0399228A1 (de) * 1989-04-29 1990-11-28 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Penemverbindungen
KR100204987B1 (ko) 1990-04-18 1999-06-15 제이코버스 코넬리스 레이서 항미생물성 퀴놀로닐 락탐
US5399679A (en) * 1992-06-16 1995-03-21 Farmitalia Carlo Erba S.R.L. (1'R,3S,4R)4-acylthio azetidinones
EP0597401A3 (en) * 1992-11-11 1995-07-26 Takeda Chemical Industries Ltd Preparation of penemes.
IT1286558B1 (it) * 1996-02-27 1998-07-15 Menarini Farma Ind Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
CN100417654C (zh) * 2004-01-09 2008-09-10 中国医学科学院医药生物技术研究所 2-苯羧酸酯青霉烯类化合物及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500457A (en) * 1977-05-09 1985-02-19 Ciba-Geigy Corporation Process for preparing thia-aza compounds with a beta-lactam ring
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
EP0013067A1 (en) * 1978-12-22 1980-07-09 Beecham Group Plc Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes
FI75163C (fi) * 1979-02-24 1988-05-09 Erba Farmitalia Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar.
US4269771A (en) * 1979-04-06 1981-05-26 Farmitalia Carlo Erba Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents
CH651037A5 (de) * 1980-06-06 1985-08-30 Sankyo Co Penem-3-carbonsaeurederivate und verfahren zu deren herstellung.
GB2079744A (en) * 1980-07-04 1982-01-27 Erba Farmitalia 6-Alkyl-2-functionalized penems
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd （６ｒ）−置換−（５ｒ）−ペネム−３−カルボン酸誘導体およびその製造法
US4411906A (en) * 1981-11-25 1983-10-25 Schering Corporation (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(2-fluoroethylthio)-penem-3-carboxylates
AT379399B (de) * 1981-12-11 1985-12-27 Erba Farmitalia Verfahren zur herstellung von optisch aktiven penemen
US4443373A (en) * 1982-03-30 1984-04-17 Schering Corporation Process for the production of antibiotic penems
US4584133A (en) * 1983-11-07 1986-04-22 Schering Corporation Process for the production of penems

Also Published As

Publication number Publication date
JPS6058988A (ja) 1985-04-05
PT79065B (en) 1986-11-14
DK382084D0 (da) 1984-08-08
NL8402478A (nl) 1985-03-01
KR910002098B1 (ko) 1991-04-03
SE463514B (sv) 1990-12-03
IT1209578B (it) 1989-08-30
FR2550533A1 (fr) 1985-02-15
FI83521B (fi) 1991-04-15
GB2144743A (en) 1985-03-13
FI83521C (fi) 1991-07-25
SE8404004L (sv) 1985-02-12
FR2550533B1 (fr) 1987-01-30
IT8422234A0 (it) 1984-08-06
PT79065A (en) 1984-09-01
GB8420236D0 (en) 1984-09-12
CH663024A5 (de) 1987-11-13
US4631150A (en) 1986-12-23
DK167926B1 (da) 1994-01-03
IL72612A (en) 1988-06-30
ES8600306A1 (es) 1985-09-16
BE900316A (fr) 1985-02-08
FI843111A (fi) 1985-02-12
DE3429102A1 (de) 1985-02-28
HU192415B (en) 1987-06-29
KR850001757A (ko) 1985-04-01
GB2144743B (en) 1987-01-28
ATA255884A (de) 1987-01-15
JPH037675B2 (fi) 1991-02-04
SE8404004D0 (sv) 1984-08-07
ES534892A0 (es) 1985-09-16
CA1279640C (en) 1991-01-29
IL72612A0 (en) 1984-11-30
DK382084A (da) 1985-02-12
GR80102B (en) 1984-12-14
HUT34984A (en) 1985-05-28
AT383808B (de) 1987-08-25
GB8321677D0 (en) 1983-09-14

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A