IL72612A - Preparation of penems - Google Patents
Preparation of penemsInfo
- Publication number
- IL72612A IL72612A IL72612A IL7261284A IL72612A IL 72612 A IL72612 A IL 72612A IL 72612 A IL72612 A IL 72612A IL 7261284 A IL7261284 A IL 7261284A IL 72612 A IL72612 A IL 72612A
- Authority
- IL
- Israel
- Prior art keywords
- penems
- preparation
- Prior art date
Links
- 150000002961 penems Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/06—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838321677A GB8321677D0 (en) | 1983-08-11 | 1983-08-11 | Preparation of penems |
Publications (2)
Publication Number | Publication Date |
---|---|
IL72612A0 IL72612A0 (en) | 1984-11-30 |
IL72612A true IL72612A (en) | 1988-06-30 |
Family
ID=10547172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL72612A IL72612A (en) | 1983-08-11 | 1984-08-07 | Preparation of penems |
Country Status (20)
Country | Link |
---|---|
US (1) | US4631150A (fi) |
JP (1) | JPS6058988A (fi) |
KR (1) | KR910002098B1 (fi) |
AT (1) | AT383808B (fi) |
BE (1) | BE900316A (fi) |
CA (1) | CA1279640C (fi) |
CH (1) | CH663024A5 (fi) |
DE (1) | DE3429102A1 (fi) |
DK (1) | DK167926B1 (fi) |
ES (1) | ES534892A0 (fi) |
FI (1) | FI83521C (fi) |
FR (1) | FR2550533B1 (fi) |
GB (2) | GB8321677D0 (fi) |
GR (1) | GR80102B (fi) |
HU (1) | HU192415B (fi) |
IL (1) | IL72612A (fi) |
IT (1) | IT1209578B (fi) |
NL (1) | NL8402478A (fi) |
PT (1) | PT79065B (fi) |
SE (1) | SE463514B (fi) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8416651D0 (en) * | 1984-06-29 | 1984-08-01 | Erba Farmitalia | Penem derivatives |
US5215997A (en) * | 1985-09-11 | 1993-06-01 | Ciba-Geigy Corporation | Synthesis of beta-lactam compounds |
DE3688960D1 (de) * | 1985-09-11 | 1993-10-07 | Ciba Geigy | Synthese von Beta-Lactamverbindungen. |
ATE159021T1 (de) * | 1986-01-17 | 1997-10-15 | Beecham Group Plc | Verfahren zur herstellung von penem derivaten und zwischenprodukte zu dieser herstellung |
EP0233155A1 (de) * | 1986-02-14 | 1987-08-19 | Ciba-Geigy Ag | Aminoacyloxymethyl-Verbindungen |
US5215891A (en) * | 1986-10-15 | 1993-06-01 | Farmitalia Carlo Erba | Process for preparing penems |
EP0279781A3 (de) * | 1987-02-17 | 1989-07-26 | Ciba-Geigy Ag | Verfahren zur Herstellung von 4-Acetoxy-3-hydroxyethyl-azetidinon |
US5312914A (en) * | 1987-02-17 | 1994-05-17 | Ciba-Geigy Corp | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone |
GB8713515D0 (en) * | 1987-06-10 | 1987-07-15 | Erba Farmitalia | Methoxymethyl compounds |
GB2206578B (en) * | 1987-07-07 | 1991-07-03 | Erba Carlo Spa | Process for the preparation of penems |
US5364768A (en) * | 1987-07-07 | 1994-11-15 | Farmitalia Carlo Erba S.R.L. | Process for the preparation of penems |
US5191075A (en) * | 1988-10-19 | 1993-03-02 | Pfizer Inc | Process for the preparation of penems |
US4992543A (en) * | 1988-10-19 | 1991-02-12 | Pfizer Inc. | Penem derivatives |
EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
EP0399228A1 (de) * | 1989-04-29 | 1990-11-28 | Hoechst Aktiengesellschaft | Verfahren zur Herstellung von Penemverbindungen |
US5198544A (en) * | 1989-04-29 | 1993-03-30 | Hoechst Aktiengesellschaft | Process for the preparation of penem compounds |
ATE193890T1 (de) | 1990-04-18 | 2000-06-15 | Procter & Gamble Pharma | Antimikrobielle chinolonyl-lactame |
US5399679A (en) * | 1992-06-16 | 1995-03-21 | Farmitalia Carlo Erba S.R.L. | (1'R,3S,4R)4-acylthio azetidinones |
EP0597401A3 (en) * | 1992-11-11 | 1995-07-26 | Takeda Chemical Industries Ltd | Preparation of penemes. |
IT1286558B1 (it) * | 1996-02-27 | 1998-07-15 | Menarini Farma Ind | Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici |
CN100417654C (zh) * | 2004-01-09 | 2008-09-10 | 中国医学科学院医药生物技术研究所 | 2-苯羧酸酯青霉烯类化合物及其制备方法和应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4500457A (en) * | 1977-05-09 | 1985-02-19 | Ciba-Geigy Corporation | Process for preparing thia-aza compounds with a beta-lactam ring |
US4168314A (en) * | 1977-11-17 | 1979-09-18 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid |
EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
EP0013067A1 (en) * | 1978-12-22 | 1980-07-09 | Beecham Group Plc | Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes |
IT1193922B (it) * | 1979-02-24 | 1988-08-31 | Erba Farmitalia | Agenti antibatterici ed inibitori di beta -lattamasi e loro preparazione |
US4269771A (en) * | 1979-04-06 | 1981-05-26 | Farmitalia Carlo Erba | Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents |
FR2483924A1 (fr) * | 1980-06-06 | 1981-12-11 | Sankyo Co | Derives d'acide peneme-3-carboxylique, leurs procedes de preparation et leur application en therapeutique |
GB2079744A (en) * | 1980-07-04 | 1982-01-27 | Erba Farmitalia | 6-Alkyl-2-functionalized penems |
US4347183A (en) * | 1981-02-02 | 1982-08-31 | Schering Corporation | Process for the synthesis of penems and carbapenems |
JPS588084A (ja) * | 1981-07-08 | 1983-01-18 | Takeda Chem Ind Ltd | (6r)−置換−(5r)−ペネム−3−カルボン酸誘導体およびその製造法 |
US4411906A (en) * | 1981-11-25 | 1983-10-25 | Schering Corporation | (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(2-fluoroethylthio)-penem-3-carboxylates |
SU1389680A3 (ru) * | 1981-12-11 | 1988-04-15 | Фармиталия Карло Эрба С.П.А. (Фирма) | Способ получени оптически активных пенемов или их солей с щелочными металлами |
US4443373A (en) * | 1982-03-30 | 1984-04-17 | Schering Corporation | Process for the production of antibiotic penems |
US4584133A (en) * | 1983-11-07 | 1986-04-22 | Schering Corporation | Process for the production of penems |
-
1983
- 1983-08-11 GB GB838321677A patent/GB8321677D0/en active Pending
-
1984
- 1984-08-03 ES ES534892A patent/ES534892A0/es active Granted
- 1984-08-06 IT IT8422234A patent/IT1209578B/it active
- 1984-08-06 US US06/637,878 patent/US4631150A/en not_active Expired - Lifetime
- 1984-08-07 SE SE8404004A patent/SE463514B/sv not_active IP Right Cessation
- 1984-08-07 DE DE19843429102 patent/DE3429102A1/de not_active Ceased
- 1984-08-07 AT AT0255884A patent/AT383808B/de not_active IP Right Cessation
- 1984-08-07 IL IL72612A patent/IL72612A/xx not_active IP Right Cessation
- 1984-08-07 FR FR8412466A patent/FR2550533B1/fr not_active Expired
- 1984-08-08 DK DK382084A patent/DK167926B1/da not_active IP Right Cessation
- 1984-08-08 BE BE0/213460A patent/BE900316A/fr not_active IP Right Cessation
- 1984-08-08 JP JP59165031A patent/JPS6058988A/ja active Granted
- 1984-08-08 FI FI843111A patent/FI83521C/fi not_active IP Right Cessation
- 1984-08-09 GB GB08420236A patent/GB2144743B/en not_active Expired
- 1984-08-10 KR KR1019840004797A patent/KR910002098B1/ko not_active IP Right Cessation
- 1984-08-10 HU HU843056A patent/HU192415B/hu not_active IP Right Cessation
- 1984-08-10 GR GR80102A patent/GR80102B/el unknown
- 1984-08-10 CH CH3855/84A patent/CH663024A5/de not_active IP Right Cessation
- 1984-08-10 CA CA000460795A patent/CA1279640C/en not_active Expired - Fee Related
- 1984-08-10 PT PT79065A patent/PT79065B/pt not_active IP Right Cessation
- 1984-08-10 NL NL8402478A patent/NL8402478A/xx not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void | ||
MM9K | Patent not in force due to non-payment of renewal fees |