FI840743A - N-(3-trifluormetylfenyl)-n'- propargylpiperazin, dess framstaellning och anvaendning. - Google Patents

N-(3-trifluormetylfenyl)-n'- propargylpiperazin, dess framstaellning och anvaendning. Download PDF

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Publication number
FI840743A
FI840743A FI840743A FI840743A FI840743A FI 840743 A FI840743 A FI 840743A FI 840743 A FI840743 A FI 840743A FI 840743 A FI840743 A FI 840743A FI 840743 A FI840743 A FI 840743A
Authority
FI
Finland
Prior art keywords
trifluormethylphenyl
framstaellning och
dess framstaellning
och anvaendning
propargyl piperazine
Prior art date
Application number
FI840743A
Other languages
English (en)
Other versions
FI77658C (fi
FI77658B (fi
FI840743A0 (fi
Inventor
Rolf Banholzer
Herbert Merz
Klaus Stockhaus
Hans Michael Jennewein
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI840743A0 publication Critical patent/FI840743A0/fi
Publication of FI840743A publication Critical patent/FI840743A/fi
Application granted granted Critical
Publication of FI77658B publication Critical patent/FI77658B/fi
Publication of FI77658C publication Critical patent/FI77658C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
FI840743A 1983-02-28 1984-02-23 Foerfarande foer framstaellning av analgetiskt verkande salt av n-(3-trifluormetylfenyl)-n'-propargylpiperazin. FI77658C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833306964 DE3306964A1 (de) 1983-02-28 1983-02-28 Neues n-arylpiperazin und verfahren zu seiner herstellung
DE3306964 1983-02-28

Publications (4)

Publication Number Publication Date
FI840743A0 FI840743A0 (fi) 1984-02-23
FI840743A true FI840743A (fi) 1984-08-29
FI77658B FI77658B (fi) 1988-12-30
FI77658C FI77658C (fi) 1989-04-10

Family

ID=6192038

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840743A FI77658C (fi) 1983-02-28 1984-02-23 Foerfarande foer framstaellning av analgetiskt verkande salt av n-(3-trifluormetylfenyl)-n'-propargylpiperazin.

Country Status (25)

Country Link
US (1) US4699910A (fi)
EP (1) EP0117531B1 (fi)
JP (1) JPS59210074A (fi)
KR (1) KR910005413B1 (fi)
AT (1) ATE22289T1 (fi)
AU (1) AU562643B2 (fi)
CA (1) CA1240327A (fi)
CS (1) CS240997B2 (fi)
DD (1) DD218096A5 (fi)
DE (2) DE3306964A1 (fi)
DK (1) DK158729C (fi)
ES (7) ES8504754A1 (fi)
FI (1) FI77658C (fi)
GB (1) GB2135997B (fi)
GR (1) GR79822B (fi)
HU (1) HU190546B (fi)
IE (1) IE56938B1 (fi)
IL (1) IL71068A (fi)
NO (1) NO158803C (fi)
NZ (1) NZ207289A (fi)
PH (1) PH21982A (fi)
PL (1) PL141275B1 (fi)
PT (1) PT78155B (fi)
SU (1) SU1223844A3 (fi)
ZA (1) ZA841418B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03176457A (ja) * 1989-12-04 1991-07-31 Nippon Paint Co Ltd 新規プロパルギル化合物、その製法ならびに該化合物を含む被覆材
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
US5661163A (en) 1995-06-07 1997-08-26 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
KR20150013476A (ko) 2012-04-04 2015-02-05 아이백스 인터내셔널 게엠베하 조합요법용 약학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2993899A (en) * 1958-03-31 1961-07-25 Miles Lab Acetylenically unsaturated piperazine derivatives
NL6607959A (fi) * 1965-06-10 1966-12-12
DE1545561A1 (de) * 1965-08-23 1969-12-11 Acraf Verfahren zur Herstellung von pharmakologisch aktiven N,N-disubstituierten 1-Aryl-3-aminopropinen
FR2187311B1 (fi) * 1972-06-02 1975-06-20 Bouchara Emile
GB1560271A (en) * 1977-01-14 1980-02-06 Joullie International Sa Therapeutically useful m-trifluoromethylphenylpiperazine derivatives
US4180574A (en) * 1978-12-26 1979-12-25 Abbott Laboratories Certain ovicidal piperazines
US4518712A (en) * 1980-06-30 1985-05-21 Taiho Pharmaceutical Company Limited Piperazine derivative and analgesic composition containing the same

Also Published As

Publication number Publication date
PT78155A (de) 1984-03-01
ES536414A0 (es) 1985-12-16
EP0117531A1 (de) 1984-09-05
GB2135997A (en) 1984-09-12
ES530073A0 (es) 1985-04-16
ES8504754A1 (es) 1985-04-16
HU190546B (en) 1986-09-29
PT78155B (de) 1986-07-17
ES8603447A1 (es) 1985-12-16
NO158803C (no) 1988-11-09
PH21982A (en) 1988-05-02
CS127484A2 (en) 1985-06-13
ES536412A0 (es) 1985-10-16
GB2135997B (en) 1986-02-19
JPH056545B2 (fi) 1993-01-26
DD218096A5 (de) 1985-01-30
FI77658C (fi) 1989-04-10
ES8603446A1 (es) 1985-12-16
IE840460L (en) 1984-08-28
ES536415A0 (es) 1985-12-16
DK158729C (da) 1990-11-19
GR79822B (fi) 1984-10-31
ATE22289T1 (de) 1986-10-15
FI77658B (fi) 1988-12-30
ES8603445A1 (es) 1985-12-16
IE56938B1 (en) 1992-02-12
CA1240327A (en) 1988-08-09
ES8603444A1 (es) 1985-12-16
NO158803B (no) 1988-07-25
ES536411A0 (es) 1985-10-16
AU2508584A (en) 1984-09-06
KR910005413B1 (ko) 1991-07-29
GB8405113D0 (en) 1984-04-04
EP0117531B1 (de) 1986-09-17
SU1223844A3 (ru) 1986-04-07
DE3306964A1 (de) 1984-09-06
DK102084D0 (da) 1984-02-24
US4699910A (en) 1987-10-13
IL71068A0 (en) 1984-05-31
ES8601173A1 (es) 1985-10-16
PL141275B1 (en) 1987-07-31
DE3460733D1 (en) 1986-10-23
NZ207289A (en) 1986-07-11
PL246418A1 (en) 1985-07-02
IL71068A (en) 1988-05-31
DK102084A (da) 1984-08-29
FI840743A0 (fi) 1984-02-23
CS240997B2 (en) 1986-03-13
NO840732L (no) 1984-08-29
ES536416A0 (es) 1985-12-16
ZA841418B (en) 1985-11-27
DK158729B (da) 1990-07-09
JPS59210074A (ja) 1984-11-28
ES8601174A1 (es) 1985-10-16
KR840007875A (ko) 1984-12-11
ES536413A0 (es) 1985-12-16
AU562643B2 (en) 1987-06-18

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Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BOEHRINGER INGELHEIM KG