DK102084D0 - N-(3-trifluormethylphenyl)-n'-propargylpiperazin, dets fremstilling og anvendelse - Google Patents

N-(3-trifluormethylphenyl)-n'-propargylpiperazin, dets fremstilling og anvendelse

Info

Publication number
DK102084D0
DK102084D0 DK1020/84A DK102084A DK102084D0 DK 102084 D0 DK102084 D0 DK 102084D0 DK 1020/84 A DK1020/84 A DK 1020/84A DK 102084 A DK102084 A DK 102084A DK 102084 D0 DK102084 D0 DK 102084D0
Authority
DK
Denmark
Prior art keywords
propargylpiperazine
trifluormethylphenyl
preparation
compound
salts
Prior art date
Application number
DK1020/84A
Other languages
English (en)
Other versions
DK158729B (da
DK158729C (da
DK102084A (da
Inventor
Rolf Banholzer
Herbert Merz
Klaus Stockhaus
Hans Michael Jennewein
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK102084D0 publication Critical patent/DK102084D0/da
Publication of DK102084A publication Critical patent/DK102084A/da
Publication of DK158729B publication Critical patent/DK158729B/da
Application granted granted Critical
Publication of DK158729C publication Critical patent/DK158729C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK102084A 1983-02-28 1984-02-24 N-(3-trifluormethylphenyl)-n'-propargylpiperazin, farmaceutiske praeparater, der indeholder det, dets anvendelse, samt en fremgangsmaade til fremstilling af et farmaceutisk praeparat DK158729C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3306964 1983-02-28
DE19833306964 DE3306964A1 (de) 1983-02-28 1983-02-28 Neues n-arylpiperazin und verfahren zu seiner herstellung

Publications (4)

Publication Number Publication Date
DK102084D0 true DK102084D0 (da) 1984-02-24
DK102084A DK102084A (da) 1984-08-29
DK158729B DK158729B (da) 1990-07-09
DK158729C DK158729C (da) 1990-11-19

Family

ID=6192038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK102084A DK158729C (da) 1983-02-28 1984-02-24 N-(3-trifluormethylphenyl)-n'-propargylpiperazin, farmaceutiske praeparater, der indeholder det, dets anvendelse, samt en fremgangsmaade til fremstilling af et farmaceutisk praeparat

Country Status (25)

Country Link
US (1) US4699910A (da)
EP (1) EP0117531B1 (da)
JP (1) JPS59210074A (da)
KR (1) KR910005413B1 (da)
AT (1) ATE22289T1 (da)
AU (1) AU562643B2 (da)
CA (1) CA1240327A (da)
CS (1) CS240997B2 (da)
DD (1) DD218096A5 (da)
DE (2) DE3306964A1 (da)
DK (1) DK158729C (da)
ES (7) ES530073A0 (da)
FI (1) FI77658C (da)
GB (1) GB2135997B (da)
GR (1) GR79822B (da)
HU (1) HU190546B (da)
IE (1) IE56938B1 (da)
IL (1) IL71068A (da)
NO (1) NO158803C (da)
NZ (1) NZ207289A (da)
PH (1) PH21982A (da)
PL (1) PL141275B1 (da)
PT (1) PT78155B (da)
SU (1) SU1223844A3 (da)
ZA (1) ZA841418B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03176457A (ja) * 1989-12-04 1991-07-31 Nippon Paint Co Ltd 新規プロパルギル化合物、その製法ならびに該化合物を含む被覆材
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
US5661163A (en) 1995-06-07 1997-08-26 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
EA027748B1 (ru) 2012-04-04 2017-08-31 Тева Фармасьютикалз Интернэшнл Гмбх Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2993899A (en) * 1958-03-31 1961-07-25 Miles Lab Acetylenically unsaturated piperazine derivatives
NL6607959A (da) * 1965-06-10 1966-12-12
DE1545561A1 (de) * 1965-08-23 1969-12-11 Acraf Verfahren zur Herstellung von pharmakologisch aktiven N,N-disubstituierten 1-Aryl-3-aminopropinen
FR2187311B1 (da) * 1972-06-02 1975-06-20 Bouchara Emile
GB1560271A (en) * 1977-01-14 1980-02-06 Joullie International Sa Therapeutically useful m-trifluoromethylphenylpiperazine derivatives
US4180574A (en) * 1978-12-26 1979-12-25 Abbott Laboratories Certain ovicidal piperazines
US4518712A (en) * 1980-06-30 1985-05-21 Taiho Pharmaceutical Company Limited Piperazine derivative and analgesic composition containing the same

Also Published As

Publication number Publication date
PT78155A (de) 1984-03-01
PL141275B1 (en) 1987-07-31
EP0117531A1 (de) 1984-09-05
DE3460733D1 (en) 1986-10-23
CS240997B2 (en) 1986-03-13
IL71068A0 (en) 1984-05-31
ES8601174A1 (es) 1985-10-16
ATE22289T1 (de) 1986-10-15
US4699910A (en) 1987-10-13
IE840460L (en) 1984-08-28
ES8601173A1 (es) 1985-10-16
ES8603445A1 (es) 1985-12-16
GR79822B (da) 1984-10-31
ES536414A0 (es) 1985-12-16
AU562643B2 (en) 1987-06-18
EP0117531B1 (de) 1986-09-17
KR840007875A (ko) 1984-12-11
ES8603444A1 (es) 1985-12-16
ES8603447A1 (es) 1985-12-16
DE3306964A1 (de) 1984-09-06
DK158729B (da) 1990-07-09
ES536412A0 (es) 1985-10-16
ES8504754A1 (es) 1985-04-16
ES8603446A1 (es) 1985-12-16
GB2135997A (en) 1984-09-12
DK158729C (da) 1990-11-19
DD218096A5 (de) 1985-01-30
AU2508584A (en) 1984-09-06
FI77658B (fi) 1988-12-30
IL71068A (en) 1988-05-31
FI77658C (fi) 1989-04-10
ES536416A0 (es) 1985-12-16
FI840743A (fi) 1984-08-29
NO840732L (no) 1984-08-29
CA1240327A (en) 1988-08-09
ES530073A0 (es) 1985-04-16
SU1223844A3 (ru) 1986-04-07
PL246418A1 (en) 1985-07-02
NO158803B (no) 1988-07-25
FI840743A0 (fi) 1984-02-23
IE56938B1 (en) 1992-02-12
ZA841418B (en) 1985-11-27
HU190546B (en) 1986-09-29
CS127484A2 (en) 1985-06-13
JPS59210074A (ja) 1984-11-28
DK102084A (da) 1984-08-29
GB8405113D0 (en) 1984-04-04
PT78155B (de) 1986-07-17
JPH056545B2 (da) 1993-01-26
ES536411A0 (es) 1985-10-16
NO158803C (no) 1988-11-09
NZ207289A (en) 1986-07-11
KR910005413B1 (ko) 1991-07-29
ES536415A0 (es) 1985-12-16
PH21982A (en) 1988-05-02
GB2135997B (en) 1986-02-19
ES536413A0 (es) 1985-12-16

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Legal Events

Date Code Title Description
PBP Patent lapsed