ES536411A0 - Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina - Google Patents
Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazinaInfo
- Publication number
- ES536411A0 ES536411A0 ES536411A ES536411A ES536411A0 ES 536411 A0 ES536411 A0 ES 536411A0 ES 536411 A ES536411 A ES 536411A ES 536411 A ES536411 A ES 536411A ES 536411 A0 ES536411 A0 ES 536411A0
- Authority
- ES
- Spain
- Prior art keywords
- propargil
- trifluoromethylphenyl
- piperazine
- preparing
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833306964 DE3306964A1 (de) | 1983-02-28 | 1983-02-28 | Neues n-arylpiperazin und verfahren zu seiner herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8601173A1 ES8601173A1 (es) | 1985-10-16 |
| ES536411A0 true ES536411A0 (es) | 1985-10-16 |
Family
ID=6192038
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES530073A Expired ES8504754A1 (es) | 1983-02-28 | 1984-02-27 | Procedimiento para preparar la n-(3-trifluorometil fenil)-n-propargil-piperazina. |
| ES536412A Expired ES8601174A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536414A Expired ES8603445A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536413A Expired ES8603444A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536411A Granted ES536411A0 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536415A Expired ES8603446A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536416A Granted ES536416A0 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES530073A Expired ES8504754A1 (es) | 1983-02-28 | 1984-02-27 | Procedimiento para preparar la n-(3-trifluorometil fenil)-n-propargil-piperazina. |
| ES536412A Expired ES8601174A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536414A Expired ES8603445A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536413A Expired ES8603444A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES536415A Expired ES8603446A1 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
| ES536416A Granted ES536416A0 (es) | 1983-02-28 | 1984-10-01 | Procedimiento para preparar la n-(3-trifluorometilfenil)-n'-propargil-piperazina |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4699910A (es) |
| EP (1) | EP0117531B1 (es) |
| JP (1) | JPS59210074A (es) |
| KR (1) | KR910005413B1 (es) |
| AT (1) | ATE22289T1 (es) |
| AU (1) | AU562643B2 (es) |
| CA (1) | CA1240327A (es) |
| CS (1) | CS240997B2 (es) |
| DD (1) | DD218096A5 (es) |
| DE (2) | DE3306964A1 (es) |
| DK (1) | DK158729C (es) |
| ES (7) | ES8504754A1 (es) |
| FI (1) | FI77658C (es) |
| GB (1) | GB2135997B (es) |
| GR (1) | GR79822B (es) |
| HU (1) | HU190546B (es) |
| IE (1) | IE56938B1 (es) |
| IL (1) | IL71068A (es) |
| NO (1) | NO158803C (es) |
| NZ (1) | NZ207289A (es) |
| PH (1) | PH21982A (es) |
| PL (1) | PL141275B1 (es) |
| PT (1) | PT78155B (es) |
| SU (1) | SU1223844A3 (es) |
| ZA (1) | ZA841418B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03176457A (ja) * | 1989-12-04 | 1991-07-31 | Nippon Paint Co Ltd | 新規プロパルギル化合物、その製法ならびに該化合物を含む被覆材 |
| JPH05255089A (ja) * | 1991-12-18 | 1993-10-05 | Sanwa Kagaku Kenkyusho Co Ltd | 抗ウイルス剤 |
| US5661163A (en) * | 1995-06-07 | 1997-08-26 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| AU2013243461A1 (en) | 2012-04-04 | 2014-11-06 | Teva Pharmaceuticals International Gmbh | Pharmaceutical compositions for combination therapy |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2993899A (en) * | 1958-03-31 | 1961-07-25 | Miles Lab | Acetylenically unsaturated piperazine derivatives |
| NL6607959A (es) * | 1965-06-10 | 1966-12-12 | ||
| DE1545561A1 (de) * | 1965-08-23 | 1969-12-11 | Acraf | Verfahren zur Herstellung von pharmakologisch aktiven N,N-disubstituierten 1-Aryl-3-aminopropinen |
| FR2187311B1 (es) * | 1972-06-02 | 1975-06-20 | Bouchara Emile | |
| GB1560271A (en) * | 1977-01-14 | 1980-02-06 | Joullie International Sa | Therapeutically useful m-trifluoromethylphenylpiperazine derivatives |
| US4180574A (en) * | 1978-12-26 | 1979-12-25 | Abbott Laboratories | Certain ovicidal piperazines |
| US4518712A (en) * | 1980-06-30 | 1985-05-21 | Taiho Pharmaceutical Company Limited | Piperazine derivative and analgesic composition containing the same |
-
1983
- 1983-02-28 DE DE19833306964 patent/DE3306964A1/de not_active Withdrawn
-
1984
- 1984-02-23 EP EP84101894A patent/EP0117531B1/de not_active Expired
- 1984-02-23 FI FI840743A patent/FI77658C/fi not_active IP Right Cessation
- 1984-02-23 AT AT84101894T patent/ATE22289T1/de active
- 1984-02-23 CS CS841274A patent/CS240997B2/cs unknown
- 1984-02-23 GR GR73907A patent/GR79822B/el unknown
- 1984-02-23 DE DE8484101894T patent/DE3460733D1/de not_active Expired
- 1984-02-24 DK DK102084A patent/DK158729C/da not_active IP Right Cessation
- 1984-02-24 DD DD84260319A patent/DD218096A5/de not_active IP Right Cessation
- 1984-02-27 IE IE460/84A patent/IE56938B1/en not_active IP Right Cessation
- 1984-02-27 HU HU84771A patent/HU190546B/hu not_active IP Right Cessation
- 1984-02-27 PH PH30304A patent/PH21982A/en unknown
- 1984-02-27 NO NO840732A patent/NO158803C/no unknown
- 1984-02-27 PL PL1984246418A patent/PL141275B1/pl unknown
- 1984-02-27 ZA ZA841418A patent/ZA841418B/xx unknown
- 1984-02-27 CA CA000448370A patent/CA1240327A/en not_active Expired
- 1984-02-27 ES ES530073A patent/ES8504754A1/es not_active Expired
- 1984-02-27 NZ NZ207289A patent/NZ207289A/en unknown
- 1984-02-27 SU SU843706206A patent/SU1223844A3/ru active
- 1984-02-27 PT PT78155A patent/PT78155B/pt not_active IP Right Cessation
- 1984-02-27 JP JP59035872A patent/JPS59210074A/ja active Granted
- 1984-02-27 AU AU25085/84A patent/AU562643B2/en not_active Ceased
- 1984-02-27 IL IL71068A patent/IL71068A/xx unknown
- 1984-02-28 KR KR1019840000990A patent/KR910005413B1/ko not_active IP Right Cessation
- 1984-02-28 GB GB08405113A patent/GB2135997B/en not_active Expired
- 1984-10-01 ES ES536412A patent/ES8601174A1/es not_active Expired
- 1984-10-01 ES ES536414A patent/ES8603445A1/es not_active Expired
- 1984-10-01 ES ES536413A patent/ES8603444A1/es not_active Expired
- 1984-10-01 ES ES536411A patent/ES536411A0/es active Granted
- 1984-10-01 ES ES536415A patent/ES8603446A1/es not_active Expired
- 1984-10-01 ES ES536416A patent/ES536416A0/es active Granted
-
1985
- 1985-11-22 US US06/800,525 patent/US4699910A/en not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |