FI78692B - Foerfarande foer framstaellning av farmaceutiskt anvaendbara triazolfoereningar. - Google Patents

Foerfarande foer framstaellning av farmaceutiskt anvaendbara triazolfoereningar. Download PDF

Info

Publication number
FI78692B
FI78692B FI840892A FI840892A FI78692B FI 78692 B FI78692 B FI 78692B FI 840892 A FI840892 A FI 840892A FI 840892 A FI840892 A FI 840892A FI 78692 B FI78692 B FI 78692B
Authority
FI
Finland
Prior art keywords
radical
phenyl
hydrogen
formula
trifluoromethyl
Prior art date
Application number
FI840892A
Other languages
English (en)
Finnish (fi)
Other versions
FI840892A (fi
FI840892A0 (fi
FI78692C (sv
Inventor
Francis Thomas Boyle
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of FI840892A0 publication Critical patent/FI840892A0/fi
Publication of FI840892A publication Critical patent/FI840892A/fi
Priority to FI862913A priority Critical patent/FI862913A0/fi
Publication of FI78692B publication Critical patent/FI78692B/fi
Application granted granted Critical
Publication of FI78692C publication Critical patent/FI78692C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)

Claims (9)

1. Förfarande för fraraställning av en farmaceutiskt användbar förening med formeln 5 Ö-CH2—CR1 (OH) -CR2R3 9 λ 10 väri R* är en fenylradikal som är mono- eller disubstitue-rad med halogen och/eller trifluormetyl, R^ och R3 är obe-roende av varandra väte eller en lägre alkylgrupp och R4 och R3 är oberoende av varandra väte, en amino-, lägre 15 alkyl- eller lägre alkenylgrupp, en fenyl-, fenylkarbonyl-, fenyl-lägre-alkyl, fenoxi-lägre-alkyl- eller fenyl-lägre-alkenylradikal vars fenylring eventuelit substituerats med en eller flera halogen, trifluormetyl, lägre alkylsulfonyl och/eller lägre alkoxi, eller en heterocyklyl- eller hete-20 rocyklyl-lägre-alkylradikal, i vilken heterocyklylen är en sexledad ring vilken som heteroatom eller heteroatomer inne-häller kväve och/eller syre och är eventuellt substituerad Λ O med trifluormetyl, förutsatt, att ätminstone en av R , R , R4 och R3 är annat än väte, och syraadditionssalter av 25 föreningar med formeln II, vilka innehäller basiskt kväve kännetecknat därav, att a) en epoxid med formeln /°\ CH,-CR1-CR2R3-N—N 30 >NR5 111 väri R^·, R2, R3, R4 och R3 är som ovan definierats, antingen som sädan eller bildad in situ, omsätts med en azol med for-35 meln 32 78692 ( > 5 med undantag av föreningar, i vilka R4 och R3 är vardera O O 1 väte, R och R är vardera metyl och R·1· är en med halogen mono- eller disbustituerad fenylradikal, och föreningar, i vilka R4 och R3 är vardera väte, den ena av radikalerna R2 och R är väte och den andra är metyl och R är en med fluor 10 disubstituerad fenylradikal, eller b) en epoxid med formeln N N-CH2-CR1n^^ V 15 ^^^CR2R3 väri R*, R2 och R3 är som ovan definierats, antingen som sä-dan eller bildad in situ omsätts med en azol med formeln HN—N r*A n Xr5 VI väri R4 och R3 är som ovan definierats, eller c) en halogenförening med formeln 25 z-ch2-cr1(oh)-cr2r3z VIIA eller
30 N—N-CH2-CR1 (OH)-CR2R3Z 0 o 3 2 i vilka R , R och R är som ovan definierats och Z är halo-35 gen, företrädesvis brom eller jod, omsätts med en azol med formeln VI, med undantag av föreningar, i vilka R4 och R5
FI840892A 1983-03-08 1984-03-06 Förfarande för framställning av farmaceutiskt användbara triazolföreni ngar FI78692C (sv)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI862913A FI862913A0 (fi) 1983-03-08 1986-07-11 Antifungala azolfoereningar.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8306351 1983-03-08
GB838306351A GB8306351D0 (en) 1983-03-08 1983-03-08 Azole fungicides

Publications (4)

Publication Number Publication Date
FI840892A0 FI840892A0 (fi) 1984-03-06
FI840892A FI840892A (fi) 1984-09-09
FI78692B true FI78692B (fi) 1989-05-31
FI78692C FI78692C (sv) 1989-09-11

Family

ID=10539169

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840892A FI78692C (sv) 1983-03-08 1984-03-06 Förfarande för framställning av farmaceutiskt användbara triazolföreni ngar

Country Status (19)

Country Link
US (1) US4625036A (sv)
EP (1) EP0122693B1 (sv)
JP (1) JPS59175475A (sv)
AT (1) ATE28194T1 (sv)
AU (1) AU563978B2 (sv)
DE (1) DE3464605D1 (sv)
DK (1) DK164499C (sv)
ES (2) ES8601973A1 (sv)
FI (1) FI78692C (sv)
GB (1) GB8306351D0 (sv)
GR (1) GR79780B (sv)
HU (1) HU191258B (sv)
IE (1) IE56905B1 (sv)
IL (1) IL71128A (sv)
NO (1) NO162719C (sv)
NZ (1) NZ207412A (sv)
PT (1) PT78206B (sv)
YU (2) YU43666B (sv)
ZA (1) ZA841307B (sv)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992454A (en) * 1983-03-16 1991-02-12 Pfizer Inc. Antifungal 1,3-bis (1H-1,2,4-triazol-1-yl)-2-aryl butan-2-ols and derivatives thereof
DK159205C (da) * 1983-03-16 1991-03-04 Pfizer Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion
GB8313235D0 (en) * 1983-05-13 1983-06-22 Pfizer Ltd Antifungal agents
DE3325313A1 (de) * 1983-07-13 1985-01-31 Bayer Ag, 5090 Leverkusen Fungizide mittel, deren herstellung und verwendung
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
DE3440117A1 (de) * 1984-11-02 1986-05-15 Bayer Ag, 5090 Leverkusen Substituierte azolylcyclopropyl-azolylmethyl-carbinol-derivate
GB8614712D0 (en) * 1986-06-17 1986-07-23 Ici Plc Heterocyclic compounds
US5272167A (en) * 1986-12-10 1993-12-21 Schering Corporation Pharmaceutically active compounds
DE3869167D1 (de) * 1987-03-27 1992-04-23 Kumiai Chemical Industry Co Phenyltriazol-derivate und insectizid.
DE3730871A1 (de) * 1987-09-15 1989-03-23 Bayer Ag Bisazolyl-hydroxyalkyl-derivate
DE3737984A1 (de) * 1987-11-09 1989-08-03 Bayer Ag 3-cyano-4-phenyl-pyrrole
DE3806089A1 (de) * 1988-02-26 1989-09-07 Basf Ag Azolylmethyloxirane und diese enthaltende fungizide
HUT53889A (en) * 1988-03-04 1990-12-28 Sankyo Co. Ltd.,Jp Fungicides comprising triazole derivatives as active ingredient and process for producing the active ingredient
US5212194A (en) * 1988-07-29 1993-05-18 Basf Aktiengesellschaft Phenoxyalkyl-substituted heteroaromatics and a method for controlling pests
GB8819308D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
DE3837463A1 (de) * 1988-11-04 1990-05-10 Bayer Ag Substituierte bisazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
ES2024332A6 (es) * 1990-10-08 1992-02-16 Uriach & Cia Sa J Procedimiento para la obtencion de nuevas sulfonamidas.
EP0548553A1 (en) * 1991-11-25 1993-06-30 Takeda Chemical Industries, Ltd. Optically active azole compounds, their production and use
TW218017B (sv) * 1992-04-28 1993-12-21 Takeda Pharm Industry Co Ltd
JPH069624A (ja) * 1992-06-24 1994-01-18 Ikeda Mohandou:Kk トリアゾール誘導体
DE4302703C2 (de) * 1993-02-01 1997-02-13 Schulman A Gmbh Flammfeste, halogenfreie Polyamidmasse und Verfahren zu ihrer Herstellung
ES2062941B1 (es) * 1993-03-15 1995-10-01 Uriach & Cia Sa J Nuevos derivados de azol activos por via oral.
JPH06340636A (ja) * 1993-05-31 1994-12-13 Ss Pharmaceut Co Ltd トリアゾール誘導体又はその塩、及びこれを含有する抗真菌剤
TW297813B (sv) * 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
TW318841B (sv) 1995-02-17 1997-11-01 Takeda Pharm Industry Co Ltd
US20110237633A1 (en) * 2008-12-11 2011-09-29 Bijoy Panicker Small molecule modulators of hepatocyte growth factor (scatter factor) activity
WO2012052412A1 (de) 2010-10-22 2012-04-26 Bayer Cropscience Ag Neue heterocylische verbindungen als schädlingsbekämpfungsmittel

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038404A (en) * 1972-09-26 1977-07-26 Bayer Aktiengesellschaft 1,2,4-triazole antimycotic compositions and use thereof
DE2324424A1 (de) * 1973-05-15 1974-12-05 Bayer Ag Antimikrobielle mittel
DE2623129C3 (de) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3-(imidazol-l-yl) -propan-2-ole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
GB2104065B (en) * 1981-06-04 1985-11-06 Ciba Geigy Ag Heterocyclyl-substituted mandelic acid compounds and mandelonitriles and their use for combating microorganisms
EP0069442B1 (en) * 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
US4510148A (en) * 1982-06-12 1985-04-09 Pfizer Inc. 2-Heterocyclic-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ols as antifungal agents
FI834141A (fi) * 1982-11-16 1984-05-17 Ciba Geigy Ag Foerfarande foer framstaellning av nya arylfenyleterderivat.
DE3307218A1 (de) * 1983-03-02 1984-09-06 Bayer Ag, 5090 Leverkusen Substituierte diazolylalkyl-carbinole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
DK159205C (da) * 1983-03-16 1991-03-04 Pfizer Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion
DE3313073A1 (de) * 1983-04-12 1984-10-18 Bayer Ag, 5090 Leverkusen 1-azolyl-3-pyrazolyl-2-propanol-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
GB8313235D0 (en) * 1983-05-13 1983-06-22 Pfizer Ltd Antifungal agents
DE3319845A1 (de) * 1983-06-01 1984-12-06 Basf Ag, 6700 Ludwigshafen Arylalkylimidazolium- und -triazoliumsalze, verfahren zu ihrer herstellung und ihre verwendung als mikrozide
US4483863A (en) * 1984-01-20 1984-11-20 Pfizer Inc. Triazole antifungal agents

Also Published As

Publication number Publication date
ES530414A0 (es) 1985-11-16
HUT34169A (en) 1985-02-28
PT78206B (en) 1986-08-05
ZA841307B (en) 1984-11-28
FI840892A (fi) 1984-09-09
IE56905B1 (en) 1992-01-29
ES8603470A1 (es) 1985-12-16
DK164499C (da) 1992-11-16
DK100684D0 (da) 1984-02-24
IL71128A (en) 1988-12-30
IE840393L (en) 1984-09-08
JPH0542434B2 (sv) 1993-06-28
NO840861L (no) 1984-09-10
YU43666B (en) 1989-10-31
NZ207412A (en) 1987-01-23
DE3464605D1 (de) 1987-08-13
JPS59175475A (ja) 1984-10-04
GR79780B (sv) 1984-10-31
ES8601973A1 (es) 1985-11-16
DK100684A (da) 1984-09-09
NO162719B (no) 1989-10-30
PT78206A (en) 1984-04-01
HU191258B (en) 1987-01-28
EP0122693A1 (en) 1984-10-24
YU41284A (en) 1986-12-31
FI840892A0 (fi) 1984-03-06
AU563978B2 (en) 1987-07-30
ES537182A0 (es) 1985-12-16
US4625036A (en) 1986-11-25
YU57086A (en) 1986-12-31
AU2507684A (en) 1984-09-13
ATE28194T1 (de) 1987-07-15
FI78692C (sv) 1989-09-11
YU43599B (en) 1989-08-31
GB8306351D0 (en) 1983-04-13
EP0122693B1 (en) 1987-07-08
NO162719C (no) 1990-02-07
DK164499B (da) 1992-07-06
IL71128A0 (en) 1984-06-29

Similar Documents

Publication Publication Date Title
FI78692B (fi) Foerfarande foer framstaellning av farmaceutiskt anvaendbara triazolfoereningar.
AU602638B2 (en) Triazole antifungal agents
US5567817A (en) Triazole antifungal agents
FI86177B (fi) Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara triazolfoereningar.
US4866086A (en) Use of olefinic compounds
DE69629300T2 (de) Triazol enthaltende antifungale mittel
FI82933B (fi) Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara 1-aryl-1-fluoralkyl-2-(1h-1,2,4-triazol-1 -yl) etanoler.
EP0510036B1 (en) 2-substituted 4,5-diphenyl-imidazoles
JPH01190672A (ja) トリアゾール抗真菌剤
JPS5998072A (ja) トリアゾ−ル系抗真菌剤
PL144920B1 (en) Method of obtaining novel triazole derivatives
EP0115400B1 (en) Triazole antifungal agents
CA1293514C (en) Isoxazolylethanol derivatives
DK162046B (da) Analogifremgangsmaade til fremstilling af 2-(halogensubstitueret phenyl)-2-chlor-1-(1h-1,2,4-triazol-1-yl)-omega,omega,omega-trifluoralkan-forbindelse eller farmaceutisk acceptable syreadditionssalte deraf
FI83777B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-aryl-1-(fluorhydroxialkyl eller perfluoralkanoyl)-2-(1h-1,2,4-triazol-1-yl) etanoler.
CA2052921A1 (en) Sulfonamides as antifungal agents
US5206364A (en) Triazole antifungal agents
US5360813A (en) Sulfonamides as antifungal agents
US5344839A (en) Sulfonamides as antifungal agents
DK157134B (da) Analogifremgangsmaade til fremstilling af 1-(5-chlorpyrid-2-yl)-1-(2,4-dihalogenphenyl)-2-(1,2,4-triazol-1-yl)-ethanol-forbindelser eller deres farmaceutisk acceptable syreadditionssalte

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: IMPERIAL CHEMICAL INDUSTRIES PLC