FI77048B - Foerfarande foer framstaellning av en blodkoagulationsbefraemjande preparation pao basis av humanproteiner. - Google Patents
Foerfarande foer framstaellning av en blodkoagulationsbefraemjande preparation pao basis av humanproteiner.Info
- Publication number
- FI77048B FI77048B FI812295A FI812295A FI77048B FI 77048 B FI77048 B FI 77048B FI 812295 A FI812295 A FI 812295A FI 812295 A FI812295 A FI 812295A FI 77048 B FI77048 B FI 77048B
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- humanproteiner
- blodkoagulationsbefraemjande
- foerfarande foer
- foer framstaellning
- Prior art date
Links
- 108010018823 anti-inhibitor coagulant complex Proteins 0.000 abstract 2
- 229940105776 factor viii inhibitor bypassing activity Drugs 0.000 abstract 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 abstract 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 abstract 1
- 102000003839 Human Proteins Human genes 0.000 abstract 1
- 108090000144 Human Proteins Proteins 0.000 abstract 1
- 239000003114 blood coagulation factor Substances 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0378180A ATA378180A (de) | 1980-07-22 | 1980-07-22 | Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen |
AT378180 | 1980-07-22 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI812295L FI812295L (fi) | 1982-01-23 |
FI77048B true FI77048B (fi) | 1988-09-30 |
FI77048C FI77048C (fi) | 1989-01-10 |
Family
ID=3555339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI812295A FI77048C (fi) | 1980-07-22 | 1981-07-22 | Foerfarande foer framstaellning av en blodkoagulationsbefraemjande preparation pao basis av humanproteiner. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4395396A (fi) |
AR (1) | AR227194A1 (fi) |
AT (2) | ATA378180A (fi) |
BE (1) | BE889640A (fi) |
CH (1) | CH646061A5 (fi) |
DE (1) | DE3127318A1 (fi) |
DK (1) | DK155500C (fi) |
ES (1) | ES504000A0 (fi) |
FI (1) | FI77048C (fi) |
FR (1) | FR2487199A1 (fi) |
GB (1) | GB2080312B (fi) |
HU (1) | HU188298B (fi) |
IT (1) | IT1142032B (fi) |
LU (1) | LU83499A1 (fi) |
NL (1) | NL190268C (fi) |
NO (1) | NO157245C (fi) |
SE (1) | SE460174B (fi) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE36457T1 (de) * | 1983-05-02 | 1988-09-15 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen krankheitserregern. |
AT379510B (de) * | 1983-05-20 | 1986-01-27 | Immuno Ag | Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation |
GB8403473D0 (en) * | 1984-02-09 | 1984-03-14 | Special Trustees For St Thomas | Purification of factor viii |
AT389815B (de) * | 1984-03-09 | 1990-02-12 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten |
US5149787A (en) * | 1984-05-22 | 1992-09-22 | The Blood Center Research Foundation | Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing |
US4710381A (en) * | 1984-05-22 | 1987-12-01 | The Blood Center Of Southeastern Wisconsin | Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing |
GB8505882D0 (en) * | 1985-03-07 | 1985-04-11 | Central Blood Lab Authority | Purification of blood coagulation factor viii |
ES2045167T5 (es) * | 1987-10-23 | 1996-07-01 | Centre Regional De Transfusion | Preparacion de concentrado de factor ix humano de elevada pureza y de otras proteinas plasmaticas. |
FR2622108B1 (fr) * | 1987-10-23 | 1990-03-02 | Lille Transfusion Sanguine | Preparation de concentres de proconvertine (facteur vii), de facteur antihemophilique b (facteur ix) et d'autres proteines plasmatiques, et leur utilisation therapeutique |
DE3843126C3 (de) * | 1988-12-22 | 1994-10-06 | Octapharma Ag | Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates |
US5110907A (en) * | 1989-08-01 | 1992-05-05 | Alpha Therapeutic Corporation | Factor viii complex purification using heparin affinity chromatography |
AT395597B (de) * | 1991-01-25 | 1993-01-25 | Immuno Ag | Reagens zur bestimmung von faktor viii-aktivitaet |
DK0573605T3 (da) | 1991-03-01 | 2001-01-02 | Rhone Poulenc Rorer Int | Fremstilling af faktor IX |
AT398079B (de) * | 1991-11-04 | 1994-09-26 | Immuno Ag | Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung |
IT1262899B (it) * | 1992-03-27 | 1996-07-22 | Sclavo Spa | Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano |
FR2711371B1 (fr) * | 1993-10-18 | 1995-12-29 | Aetsrn | Procédé de préparation d'un concentré d'inter-alpha-trypsine inhibiteur à usage thérapeutique et concentré obtenu. |
DE4416166C2 (de) * | 1994-05-06 | 1997-11-20 | Immuno Ag | Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen |
DE19531637A1 (de) * | 1995-08-28 | 1997-03-06 | Immuno Ag | Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung |
SI0796623T1 (en) * | 1996-03-20 | 2005-10-31 | Baxter Aktiengesellschaft | Pharmaceutical preparation for the treatment of blood coagulation disorders |
ES2160410T3 (es) | 1997-04-08 | 2001-11-01 | Baxter Ag | Preparados de complejos de protrombina inmunotolerantes. |
AT405608B (de) * | 1997-04-08 | 1999-10-25 | Immuno Ag | Verfahren zur inaktivierung von pathogenen, insbesondere von viren, in einem biologischen material |
AT405485B (de) * | 1997-05-28 | 1999-08-25 | Immuno Ag | Eine das vwf-propeptid enthaltende pharmazeutische präparation |
AT407484B (de) * | 1997-11-12 | 2001-03-26 | Bio Prod & Bio Eng Ag | Arzneimittel zur förderung der wundheilung |
AT411997B (de) | 1999-09-14 | 2004-08-26 | Baxter Ag | Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate |
JP4199004B2 (ja) | 2000-11-07 | 2008-12-17 | クライオライフ、インコーポレイテッド | 起泡性泡沫様生体材料および方法 |
ES2325956T3 (es) * | 2002-07-23 | 2009-09-25 | BIO & BIO LICENSING SA | Farmacos y preparaciones de principios activos farmaceuticas que contienen trombina y que pueden generar trombina. |
RS20050051A (en) * | 2002-07-23 | 2007-06-04 | Bio-Products & Bio Engineering Ag., | Pharmaceutical active ingredient preparation and medicaments that contain thrombin or have a thrombin-generating capacity |
US7297336B2 (en) | 2003-09-12 | 2007-11-20 | Baxter International Inc. | Factor IXa specific antibodies displaying factor VIIIa like activity |
US20140206844A1 (en) | 2013-01-18 | 2014-07-24 | Prothera Biologics | Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material |
RU2648517C1 (ru) * | 2017-06-23 | 2018-03-26 | Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) | Способ получения лиофилизированного препарата активированного протромбинового комплекса, обладающего фактор viii-шунтирующей активностью |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1492108A1 (de) | 1964-05-04 | 1969-10-02 | Rohm & Haas | Verfahren zur Entfernung von Viren aus Blut waehrend der Entnahme oder UEbertragung |
DE2262520C3 (de) * | 1972-12-20 | 1987-02-12 | Miles Laboratories, Inc., Elkhart, Ind. | Verfahren zur Herstellung eines lyophilisierten, lagerfähigen Konzentrats aus menschlichem Plasma |
US4170590A (en) * | 1974-12-14 | 1979-10-09 | Biotest-Serum-Institut Gmbh | Ion exchanger treatment of citrate-stabilized plasma |
JPS52125609A (en) | 1976-04-09 | 1977-10-21 | Green Cross Corp:The | Purification of agglutination factor viii |
AT350726B (de) * | 1976-08-30 | 1979-06-11 | Immuno Ag | Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma |
US4081432A (en) | 1977-07-25 | 1978-03-28 | Monsanto Company | Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers |
US4286056A (en) * | 1980-01-28 | 1981-08-25 | Baxter Travenol Laboratories, Inc. | Method for making therapeutic enzyme compositions |
EP0044343B1 (en) * | 1980-01-28 | 1984-08-22 | Baxter Travenol Laboratories, Inc. | Prothrombin-containing therapeutic compositions and methods of producing enzymatically active blood clotting factors from prothrombin-containing blood fractions |
US4287180A (en) * | 1980-01-28 | 1981-09-01 | Baxter Travenol Laboratories, Inc. | Method for treating blood clotting factor inhibitors |
US4364861A (en) * | 1980-05-27 | 1982-12-21 | Cutter Laboratories, Inc. | Blood-coagulation-promoting products and methods of preparing them |
-
0
- AT AT0378180A patent/AT368883B/de active
-
1980
- 1980-07-22 AT AT0378180A patent/ATA378180A/de not_active IP Right Cessation
-
1981
- 1981-06-16 SE SE8103759A patent/SE460174B/sv not_active IP Right Cessation
- 1981-07-10 DE DE19813127318 patent/DE3127318A1/de active Granted
- 1981-07-13 NL NLAANVRAGE8103329,A patent/NL190268C/xx not_active IP Right Cessation
- 1981-07-14 US US06/283,143 patent/US4395396A/en not_active Expired - Lifetime
- 1981-07-15 ES ES504000A patent/ES504000A0/es active Granted
- 1981-07-15 BE BE0/205416A patent/BE889640A/fr not_active IP Right Cessation
- 1981-07-16 DK DK318581A patent/DK155500C/da not_active IP Right Cessation
- 1981-07-17 AR AR286129A patent/AR227194A1/es active
- 1981-07-20 LU LU83499A patent/LU83499A1/de unknown
- 1981-07-20 FR FR8114073A patent/FR2487199A1/fr active Granted
- 1981-07-21 GB GB8122392A patent/GB2080312B/en not_active Expired
- 1981-07-21 NO NO812500A patent/NO157245C/no unknown
- 1981-07-21 CH CH476881A patent/CH646061A5/de not_active IP Right Cessation
- 1981-07-22 FI FI812295A patent/FI77048C/fi not_active IP Right Cessation
- 1981-07-22 HU HU812140A patent/HU188298B/hu unknown
- 1981-07-22 IT IT23070/81A patent/IT1142032B/it active Protection Beyond IP Right Term
Also Published As
Publication number | Publication date |
---|---|
DK155500C (da) | 1989-08-07 |
AR227194A1 (es) | 1982-09-30 |
LU83499A1 (de) | 1981-10-29 |
IT8123070A0 (it) | 1981-07-22 |
DE3127318C2 (fi) | 1988-07-28 |
GB2080312A (en) | 1982-02-03 |
AT368883B (de) | 1982-11-25 |
ES8203610A1 (es) | 1982-04-16 |
DE3127318A1 (de) | 1982-04-15 |
US4395396A (en) | 1983-07-26 |
FI77048C (fi) | 1989-01-10 |
FI812295L (fi) | 1982-01-23 |
NO157245C (no) | 1988-02-24 |
ES504000A0 (es) | 1982-04-16 |
CH646061A5 (de) | 1984-11-15 |
NL190268B (nl) | 1993-08-02 |
SE8103759L (sv) | 1982-01-23 |
SE460174B (sv) | 1989-09-18 |
FR2487199B1 (fi) | 1984-11-16 |
ATA378180A (de) | 1982-04-15 |
NO157245B (no) | 1987-11-09 |
FR2487199A1 (fr) | 1982-01-29 |
HU188298B (en) | 1986-03-28 |
DK155500B (da) | 1989-04-17 |
NL190268C (nl) | 1994-01-03 |
NL8103329A (nl) | 1982-02-16 |
DK318581A (da) | 1982-01-23 |
BE889640A (fr) | 1981-11-03 |
NO812500L (no) | 1982-01-25 |
GB2080312B (en) | 1983-12-21 |
IT1142032B (it) | 1986-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MA | Patent expired |
Owner name: "IMMUNO" AKTIENGESELLSCHAFT FUER |