ES504000A0 - Procedimiento para la fabricacion de un nuevo preparado ac- tivador de la coagulacion de la sangre a base de proteinas humanas - Google Patents

Procedimiento para la fabricacion de un nuevo preparado ac- tivador de la coagulacion de la sangre a base de proteinas humanas

Info

Publication number
ES504000A0
ES504000A0 ES504000A ES504000A ES504000A0 ES 504000 A0 ES504000 A0 ES 504000A0 ES 504000 A ES504000 A ES 504000A ES 504000 A ES504000 A ES 504000A ES 504000 A0 ES504000 A0 ES 504000A0
Authority
ES
Spain
Prior art keywords
procedure
manufacture
blood coagulation
new blood
human proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES504000A
Other languages
English (en)
Other versions
ES8203610A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Immuno AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno AG filed Critical Immuno AG
Publication of ES8203610A1 publication Critical patent/ES8203610A1/es
Publication of ES504000A0 publication Critical patent/ES504000A0/es
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES504000A 1980-07-22 1981-07-15 Procedimiento para la fabricacion de un nuevo preparado ac- tivador de la coagulacion de la sangre a base de proteinas humanas Granted ES504000A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0378180A ATA378180A (de) 1980-07-22 1980-07-22 Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen

Publications (2)

Publication Number Publication Date
ES8203610A1 ES8203610A1 (es) 1982-04-16
ES504000A0 true ES504000A0 (es) 1982-04-16

Family

ID=3555339

Family Applications (1)

Application Number Title Priority Date Filing Date
ES504000A Granted ES504000A0 (es) 1980-07-22 1981-07-15 Procedimiento para la fabricacion de un nuevo preparado ac- tivador de la coagulacion de la sangre a base de proteinas humanas

Country Status (17)

Country Link
US (1) US4395396A (es)
AR (1) AR227194A1 (es)
AT (2) ATA378180A (es)
BE (1) BE889640A (es)
CH (1) CH646061A5 (es)
DE (1) DE3127318A1 (es)
DK (1) DK155500C (es)
ES (1) ES504000A0 (es)
FI (1) FI77048C (es)
FR (1) FR2487199A1 (es)
GB (1) GB2080312B (es)
HU (1) HU188298B (es)
IT (1) IT1142032B (es)
LU (1) LU83499A1 (es)
NL (1) NL190268C (es)
NO (1) NO157245C (es)
SE (1) SE460174B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3473407D1 (en) * 1983-05-02 1988-09-22 Immuno Ag Method of inactivating pathogens
AT379510B (de) * 1983-05-20 1986-01-27 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation
GB8403473D0 (en) * 1984-02-09 1984-03-14 Special Trustees For St Thomas Purification of factor viii
AT389815B (de) * 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
US4710381A (en) * 1984-05-22 1987-12-01 The Blood Center Of Southeastern Wisconsin Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
US5149787A (en) * 1984-05-22 1992-09-22 The Blood Center Research Foundation Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
DE3877529T2 (de) * 1987-10-23 1996-11-07 Centre Regional De Transfusion Herstellung von hoch-gereingtem menschlichen Faktor IX sowie anderem Plasmaproteinkonzentrat und dessen therapeutische Verwendung.
FR2622108B1 (fr) * 1987-10-23 1990-03-02 Lille Transfusion Sanguine Preparation de concentres de proconvertine (facteur vii), de facteur antihemophilique b (facteur ix) et d'autres proteines plasmatiques, et leur utilisation therapeutique
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
AT395597B (de) * 1991-01-25 1993-01-25 Immuno Ag Reagens zur bestimmung von faktor viii-aktivitaet
DE69231401T2 (de) * 1991-03-01 2001-02-08 Rhone Poulenc Rorer Int Herstellung von faktor-ix
AT398079B (de) * 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
FR2711371B1 (fr) * 1993-10-18 1995-12-29 Aetsrn Procédé de préparation d'un concentré d'inter-alpha-trypsine inhibiteur à usage thérapeutique et concentré obtenu.
DE4416166C2 (de) * 1994-05-06 1997-11-20 Immuno Ag Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen
DE19531637A1 (de) * 1995-08-28 1997-03-06 Immuno Ag Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung
DE59712322D1 (de) * 1996-03-20 2005-06-30 Baxter Ag Pharmazeutisches Präparat zur Behandlung von Blutgerinnungsstörungen
AT405608B (de) * 1997-04-08 1999-10-25 Immuno Ag Verfahren zur inaktivierung von pathogenen, insbesondere von viren, in einem biologischen material
PT973544E (pt) 1997-04-08 2001-12-28 Baxter Ag Preparacao de complexo de protrombina imunotolerante
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
AT411997B (de) 1999-09-14 2004-08-26 Baxter Ag Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate
CA2425935C (en) 2000-11-07 2011-03-29 Cryolife, Inc. Expandable foam-like biomaterials and methods
EP1523327A1 (de) * 2002-07-23 2005-04-20 Bio-Products & Bio-Engineering Aktiengesellschaft Thrombingenerierfahige und thrombinhaltige pharmazeutische wirkstoffzubereitungen und arzneimittel
AU2003246448A1 (en) * 2002-07-23 2004-02-16 Bio-Products And Bio-Engineering Aktiengesellschaft Pharmaceutically active substance preparations and drugs that are capable of generating thrombin and/or that contain thrombin
US7297336B2 (en) 2003-09-12 2007-11-20 Baxter International Inc. Factor IXa specific antibodies displaying factor VIIIa like activity
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
RU2648517C1 (ru) * 2017-06-23 2018-03-26 Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) Способ получения лиофилизированного препарата активированного протромбинового комплекса, обладающего фактор viii-шунтирующей активностью

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492108A1 (de) 1964-05-04 1969-10-02 Rohm & Haas Verfahren zur Entfernung von Viren aus Blut waehrend der Entnahme oder UEbertragung
DE2262520B2 (de) * 1972-12-20 1979-10-11 Cutter Laboratories Inc., Berkeley, Calif. (V.St.A.) Verfahren zur Herstellung eines lyophilisierten, lagerfähigen Konzentrats aus menschlichem Plasma
US4170590A (en) * 1974-12-14 1979-10-09 Biotest-Serum-Institut Gmbh Ion exchanger treatment of citrate-stabilized plasma
JPS52125609A (en) 1976-04-09 1977-10-21 Green Cross Corp:The Purification of agglutination factor viii
AT350726B (de) * 1976-08-30 1979-06-11 Immuno Ag Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma
US4081432A (en) 1977-07-25 1978-03-28 Monsanto Company Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers
US4287180A (en) * 1980-01-28 1981-09-01 Baxter Travenol Laboratories, Inc. Method for treating blood clotting factor inhibitors
EP0044343B1 (en) * 1980-01-28 1984-08-22 Baxter Travenol Laboratories, Inc. Prothrombin-containing therapeutic compositions and methods of producing enzymatically active blood clotting factors from prothrombin-containing blood fractions
US4286056A (en) * 1980-01-28 1981-08-25 Baxter Travenol Laboratories, Inc. Method for making therapeutic enzyme compositions
US4364861A (en) * 1980-05-27 1982-12-21 Cutter Laboratories, Inc. Blood-coagulation-promoting products and methods of preparing them

Also Published As

Publication number Publication date
FR2487199B1 (es) 1984-11-16
SE8103759L (sv) 1982-01-23
DK155500B (da) 1989-04-17
AT368883B (de) 1982-11-25
FR2487199A1 (fr) 1982-01-29
NO157245C (no) 1988-02-24
NO157245B (no) 1987-11-09
GB2080312A (en) 1982-02-03
NL190268B (nl) 1993-08-02
HU188298B (en) 1986-03-28
ES8203610A1 (es) 1982-04-16
NL190268C (nl) 1994-01-03
DK318581A (da) 1982-01-23
ATA378180A (de) 1982-04-15
SE460174B (sv) 1989-09-18
DE3127318A1 (de) 1982-04-15
FI77048C (fi) 1989-01-10
AR227194A1 (es) 1982-09-30
FI812295L (fi) 1982-01-23
CH646061A5 (de) 1984-11-15
NL8103329A (nl) 1982-02-16
NO812500L (no) 1982-01-25
IT8123070A0 (it) 1981-07-22
US4395396A (en) 1983-07-26
DE3127318C2 (es) 1988-07-28
IT1142032B (it) 1986-10-08
LU83499A1 (de) 1981-10-29
GB2080312B (en) 1983-12-21
DK155500C (da) 1989-08-07
FI77048B (fi) 1988-09-30
BE889640A (fr) 1981-11-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020220