IT1142032B - Preparato che favorisce la coagulazione del sangue a base di proteine umani, nonche' procedimento per la preparazione - Google Patents

Preparato che favorisce la coagulazione del sangue a base di proteine umani, nonche' procedimento per la preparazione

Info

Publication number
IT1142032B
IT1142032B IT23070/81A IT2307081A IT1142032B IT 1142032 B IT1142032 B IT 1142032B IT 23070/81 A IT23070/81 A IT 23070/81A IT 2307081 A IT2307081 A IT 2307081A IT 1142032 B IT1142032 B IT 1142032B
Authority
IT
Italy
Prior art keywords
preparation
blood coagulation
human protein
based blood
procedure
Prior art date
Application number
IT23070/81A
Other languages
English (en)
Other versions
IT8123070A0 (it
Inventor
Johann Eibl
Otto Schwarz
Fritz Elsinger
Anton Philapitsch
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of IT8123070A0 publication Critical patent/IT8123070A0/it
Application granted granted Critical
Publication of IT1142032B publication Critical patent/IT1142032B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IT23070/81A 1980-07-22 1981-07-22 Preparato che favorisce la coagulazione del sangue a base di proteine umani, nonche' procedimento per la preparazione IT1142032B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0378180A ATA378180A (de) 1980-07-22 1980-07-22 Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen

Publications (2)

Publication Number Publication Date
IT8123070A0 IT8123070A0 (it) 1981-07-22
IT1142032B true IT1142032B (it) 1986-10-08

Family

ID=3555339

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23070/81A IT1142032B (it) 1980-07-22 1981-07-22 Preparato che favorisce la coagulazione del sangue a base di proteine umani, nonche' procedimento per la preparazione

Country Status (17)

Country Link
US (1) US4395396A (it)
AR (1) AR227194A1 (it)
AT (2) ATA378180A (it)
BE (1) BE889640A (it)
CH (1) CH646061A5 (it)
DE (1) DE3127318A1 (it)
DK (1) DK155500C (it)
ES (1) ES504000A0 (it)
FI (1) FI77048C (it)
FR (1) FR2487199A1 (it)
GB (1) GB2080312B (it)
HU (1) HU188298B (it)
IT (1) IT1142032B (it)
LU (1) LU83499A1 (it)
NL (1) NL190268C (it)
NO (1) NO157245C (it)
SE (1) SE460174B (it)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE36457T1 (de) * 1983-05-02 1988-09-15 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen krankheitserregern.
AT379510B (de) * 1983-05-20 1986-01-27 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation
GB8403473D0 (en) * 1984-02-09 1984-03-14 Special Trustees For St Thomas Purification of factor viii
AT389815B (de) * 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
US5149787A (en) * 1984-05-22 1992-09-22 The Blood Center Research Foundation Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
US4710381A (en) * 1984-05-22 1987-12-01 The Blood Center Of Southeastern Wisconsin Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
FR2622108B1 (fr) * 1987-10-23 1990-03-02 Lille Transfusion Sanguine Preparation de concentres de proconvertine (facteur vii), de facteur antihemophilique b (facteur ix) et d'autres proteines plasmatiques, et leur utilisation therapeutique
EP0317376B2 (fr) * 1987-10-23 1996-04-03 Centre Regional De Transfusion Sanguine De Lille Préparation de concentré de facteur IX humain de haute pureté et d'autres protéines plasmatiques
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
AT395597B (de) * 1991-01-25 1993-01-25 Immuno Ag Reagens zur bestimmung von faktor viii-aktivitaet
ES2150914T3 (es) 1991-03-01 2000-12-16 Rhone Poulenc Rorer Int Preparacion de factor ix.
AT398079B (de) * 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
FR2711371B1 (fr) * 1993-10-18 1995-12-29 Aetsrn Procédé de préparation d'un concentré d'inter-alpha-trypsine inhibiteur à usage thérapeutique et concentré obtenu.
DE4416166C2 (de) * 1994-05-06 1997-11-20 Immuno Ag Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen
DE19531637A1 (de) * 1995-08-28 1997-03-06 Immuno Ag Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung
DK0796623T3 (da) * 1996-03-20 2005-08-01 Baxter Ag Farmaceutisk præparat til behandling af blodkoagulationslidelser
AT405608B (de) * 1997-04-08 1999-10-25 Immuno Ag Verfahren zur inaktivierung von pathogenen, insbesondere von viren, in einem biologischen material
JP3976351B2 (ja) * 1997-04-08 2007-09-19 バクスター・アクチエンゲゼルシャフト 免疫寛容プロトロンビン複合体の調製
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
AT411997B (de) 1999-09-14 2004-08-26 Baxter Ag Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate
JP4199004B2 (ja) 2000-11-07 2008-12-17 クライオライフ、インコーポレイテッド 起泡性泡沫様生体材料および方法
RS52080B (sr) * 2002-07-23 2012-06-30 Bio & Bio Licensing Sa Farmaceutski aktivna supstanca preparata i lekova koji su u stanju da stvaraju trombin i/ili da sadrže trombin
RS20050051A (en) * 2002-07-23 2007-06-04 Bio-Products & Bio Engineering Ag., Pharmaceutical active ingredient preparation and medicaments that contain thrombin or have a thrombin-generating capacity
US7297336B2 (en) 2003-09-12 2007-11-20 Baxter International Inc. Factor IXa specific antibodies displaying factor VIIIa like activity
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
RU2648517C1 (ru) * 2017-06-23 2018-03-26 Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) Способ получения лиофилизированного препарата активированного протромбинового комплекса, обладающего фактор viii-шунтирующей активностью

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492108A1 (de) 1964-05-04 1969-10-02 Rohm & Haas Verfahren zur Entfernung von Viren aus Blut waehrend der Entnahme oder UEbertragung
DE2262520B2 (de) * 1972-12-20 1979-10-11 Cutter Laboratories Inc., Berkeley, Calif. (V.St.A.) Verfahren zur Herstellung eines lyophilisierten, lagerfähigen Konzentrats aus menschlichem Plasma
US4170590A (en) * 1974-12-14 1979-10-09 Biotest-Serum-Institut Gmbh Ion exchanger treatment of citrate-stabilized plasma
JPS52125609A (en) 1976-04-09 1977-10-21 Green Cross Corp:The Purification of agglutination factor viii
AT350726B (de) * 1976-08-30 1979-06-11 Immuno Ag Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma
US4081432A (en) 1977-07-25 1978-03-28 Monsanto Company Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers
WO1981002105A1 (en) * 1980-01-28 1981-08-06 Baxter Travenol Lab Therapeutic compositions & methods for manufacture and use
US4287180A (en) * 1980-01-28 1981-09-01 Baxter Travenol Laboratories, Inc. Method for treating blood clotting factor inhibitors
US4286056A (en) * 1980-01-28 1981-08-25 Baxter Travenol Laboratories, Inc. Method for making therapeutic enzyme compositions
US4364861A (en) * 1980-05-27 1982-12-21 Cutter Laboratories, Inc. Blood-coagulation-promoting products and methods of preparing them

Also Published As

Publication number Publication date
AR227194A1 (es) 1982-09-30
SE460174B (sv) 1989-09-18
AT368883B (de) 1982-11-25
FR2487199B1 (it) 1984-11-16
NO812500L (no) 1982-01-25
DK155500C (da) 1989-08-07
LU83499A1 (de) 1981-10-29
NO157245B (no) 1987-11-09
CH646061A5 (de) 1984-11-15
DK155500B (da) 1989-04-17
ES8203610A1 (es) 1982-04-16
GB2080312A (en) 1982-02-03
FI77048C (fi) 1989-01-10
GB2080312B (en) 1983-12-21
BE889640A (fr) 1981-11-03
US4395396A (en) 1983-07-26
ES504000A0 (es) 1982-04-16
NL190268B (nl) 1993-08-02
HU188298B (en) 1986-03-28
NO157245C (no) 1988-02-24
ATA378180A (de) 1982-04-15
DK318581A (da) 1982-01-23
IT8123070A0 (it) 1981-07-22
SE8103759L (sv) 1982-01-23
FI77048B (fi) 1988-09-30
DE3127318C2 (it) 1988-07-28
NL8103329A (nl) 1982-02-16
FI812295L (fi) 1982-01-23
NL190268C (nl) 1994-01-03
DE3127318A1 (de) 1982-04-15
FR2487199A1 (fr) 1982-01-29

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 288

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 288, 19920513; IMMUNO AKTIENGESELLSCHAFT

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970528