RS52080B - Farmaceutski aktivna supstanca preparata i lekova koji su u stanju da stvaraju trombin i/ili da sadrže trombin - Google Patents

Farmaceutski aktivna supstanca preparata i lekova koji su u stanju da stvaraju trombin i/ili da sadrže trombin

Info

Publication number
RS52080B
RS52080B YU20050052A YUP5205A RS52080B RS 52080 B RS52080 B RS 52080B YU 20050052 A YU20050052 A YU 20050052A YU P5205 A YUP5205 A YU P5205A RS 52080 B RS52080 B RS 52080B
Authority
RS
Serbia
Prior art keywords
thrombin
generating
plasma
production
medicament
Prior art date
Application number
YU20050052A
Other languages
English (en)
Inventor
Johann Eibl
Original Assignee
Bio & Bio Licensing Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio & Bio Licensing Sa filed Critical Bio & Bio Licensing Sa
Publication of RS20050052A publication Critical patent/RS20050052A/sr
Publication of RS52080B publication Critical patent/RS52080B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Farmaceutski aktivna supstanca za dobijanje lekova koja ima sposobnostgenerisanja trombina ili sadrži trombin, naznačena time, što sadrži:(A) protrombin dobijen iz plazme ili genetskim inžinjeringom (faktor kaogulacije II)(B) faktore koagulacije V, VIII, IX, X dobijene iz plazme ili genetskim inžinjeringom koji mogu biti, u najmanju ruku, delimično prisutni u aktivisanom stanju, i faktor koagulacije Xla dobijen iz plazme ili genetskim inžinjeringom(C) fosfolipide aktivne u koagulaciji koji ne sadrže prione sposobne da izazovu infekciju, pri čemu su fosfolipidi u datom slučaju sadržani u lipozomima.Prijava sadrži još 13 patentnih zahteva.
YU20050052A 2002-07-23 2003-07-21 Farmaceutski aktivna supstanca preparata i lekova koji su u stanju da stvaraju trombin i/ili da sadrže trombin RS52080B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT11132002 2002-07-23
PCT/AT2003/000204 WO2004011023A1 (de) 2002-07-23 2003-07-21 Thrombingenerierfähige und thrombinhältige pharmazeutische wirkstoffzubereitungen und arzneimittel

Publications (2)

Publication Number Publication Date
RS20050052A RS20050052A (en) 2007-06-04
RS52080B true RS52080B (sr) 2012-06-30

Family

ID=30773865

Family Applications (1)

Application Number Title Priority Date Filing Date
YU20050052A RS52080B (sr) 2002-07-23 2003-07-21 Farmaceutski aktivna supstanca preparata i lekova koji su u stanju da stvaraju trombin i/ili da sadrže trombin

Country Status (9)

Country Link
US (2) US7371722B2 (sr)
EP (2) EP1528930B1 (sr)
AT (1) ATE428440T1 (sr)
AU (2) AU2003246448A1 (sr)
DE (1) DE50311422D1 (sr)
DK (1) DK1528930T3 (sr)
ES (1) ES2325956T3 (sr)
RS (1) RS52080B (sr)
WO (2) WO2004011023A1 (sr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
ES2926359T3 (es) 2003-12-01 2022-10-25 Novo Nordisk Healthcare Ag Filtración de virus de composiciones líquidas del Factor VII
US20090186077A1 (en) * 2006-02-15 2009-07-23 Ying Jackie Y Thermo-responsive materials
EP2305289A1 (en) * 2009-09-16 2011-04-06 Bio-Products & Bio-Engineering Aktiengesellschaft Medicinal products for the treatment of blood coagulation disorders
GB201009676D0 (en) * 2010-06-10 2010-07-21 Glaxosmithkline Biolog Sa Novel process
EP3834851A1 (en) 2010-12-30 2021-06-16 Laboratoire Français du Fractionnement et des Biotechnologies Glycols as pathogen inactive agents
IL230150A0 (en) * 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing zymogens
CN112011527B (zh) * 2020-08-25 2023-07-07 长春雷允上药业有限公司 一种凝血酶的制备方法
CN116194080A (zh) 2020-09-23 2023-05-30 奥姆里克斯生物药品有限公司 止血制剂及其用途
CN113018423A (zh) * 2021-03-12 2021-06-25 上海利康瑞生物工程有限公司 一种基于乙醇梯度洗脱的止血材料及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188318A (en) * 1975-06-16 1980-02-12 Edward Shanbrom Simplified method for preparation of high yield, high purity Factor VIII concentrate
AT350726B (de) * 1976-08-30 1979-06-11 Immuno Ag Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma
US4286056A (en) * 1980-01-28 1981-08-25 Baxter Travenol Laboratories, Inc. Method for making therapeutic enzyme compositions
WO1981002105A1 (en) * 1980-01-28 1981-08-06 Baxter Travenol Lab Therapeutic compositions & methods for manufacture and use
AT368883B (de) * 1980-07-22 1982-11-25 Immuno Ag Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen
JPS63243032A (ja) * 1987-03-27 1988-10-07 Green Cross Corp:The トロンビンの加熱処理方法
DE4416166C2 (de) * 1994-05-06 1997-11-20 Immuno Ag Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen
DE4430205A1 (de) 1994-08-26 1996-02-29 Behringwerke Ag Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung
JP3976351B2 (ja) * 1997-04-08 2007-09-19 バクスター・アクチエンゲゼルシャフト 免疫寛容プロトロンビン複合体の調製
US5981254A (en) * 1997-10-30 1999-11-09 Haemacure Corporation Process for producing thrombin from plasma
DE19824306A1 (de) * 1998-05-21 1999-11-25 Michael Sittinger Autologe Fibrinkleber
EP1523327A1 (de) * 2002-07-23 2005-04-20 Bio-Products & Bio-Engineering Aktiengesellschaft Thrombingenerierfahige und thrombinhaltige pharmazeutische wirkstoffzubereitungen und arzneimittel

Also Published As

Publication number Publication date
EP1528930A1 (de) 2005-05-11
AU2003246448A1 (en) 2004-02-16
DE50311422D1 (de) 2009-05-28
WO2004011024A8 (de) 2007-05-18
WO2004011023A1 (de) 2004-02-05
EP2082748A1 (de) 2009-07-29
US20090123453A1 (en) 2009-05-14
DK1528930T3 (da) 2009-08-03
US7371722B2 (en) 2008-05-13
AU2003246449A8 (en) 2004-02-16
AU2003246449A1 (en) 2004-02-16
RS20050052A (en) 2007-06-04
WO2004011024A1 (de) 2004-02-05
EP1528930B1 (de) 2009-04-15
ATE428440T1 (de) 2009-05-15
US20050192222A1 (en) 2005-09-01
ES2325956T3 (es) 2009-09-25

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