FI751654A - - Google Patents
Info
- Publication number
- FI751654A FI751654A FI751654A FI751654A FI751654A FI 751654 A FI751654 A FI 751654A FI 751654 A FI751654 A FI 751654A FI 751654 A FI751654 A FI 751654A FI 751654 A FI751654 A FI 751654A
- Authority
- FI
- Finland
- Prior art keywords
- beta
- methylpyrazolin
- naphthoxyethyl
- salts
- naphthoxyethylhydrazine
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 2-beta-naphthoxyethyl halide Chemical class 0.000 abstract 1
- BORMNCXGATVZMD-UHFFFAOYSA-N 2-naphthalen-2-yloxyethylhydrazine Chemical compound C1=CC=CC2=CC(OCCNN)=CC=C21 BORMNCXGATVZMD-UHFFFAOYSA-N 0.000 abstract 1
- WGVHNCAJPFIFCR-UHFFFAOYSA-N 5-methyl-1,2-dihydropyrazol-3-one Chemical compound CC1=CC(O)=NN1 WGVHNCAJPFIFCR-UHFFFAOYSA-N 0.000 abstract 1
- INCLABAHEPQBCG-UHFFFAOYSA-N 5-methyl-2-(2-naphthalen-2-yloxyethyl)-1h-pyrazol-3-one Chemical compound N1C(C)=CC(=O)N1CCOC1=CC=C(C=CC=C2)C2=C1 INCLABAHEPQBCG-UHFFFAOYSA-N 0.000 abstract 1
- WOFAGNLBCJWEOE-UHFFFAOYSA-N Benzyl acetoacetate Chemical compound CC(=O)CC(=O)OCC1=CC=CC=C1 WOFAGNLBCJWEOE-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003385 sodium Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000002537 thrombolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2427272 | 1974-06-06 | ||
| DE2427272A DE2427272C3 (de) | 1974-06-06 | 1974-06-06 | 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI751654A true FI751654A (pl) | 1975-12-07 |
| FI57586B FI57586B (fi) | 1980-05-30 |
| FI57586C FI57586C (fi) | 1980-09-10 |
Family
ID=5917444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI751654A FI57586C (fi) | 1974-06-06 | 1975-06-04 | Foerfarande foer framstaellning av terapeutiskt anvaendbart 1-(2-(beta-naftyloxi)-etyl)-3-metyl-pyrazolon-(5) |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US4053621A (pl) |
| JP (1) | JPS5840544B2 (pl) |
| AR (3) | AR207044A1 (pl) |
| AT (1) | AT342584B (pl) |
| BE (1) | BE829850A (pl) |
| BG (3) | BG24410A3 (pl) |
| CA (1) | CA1051001A (pl) |
| CH (3) | CH612673A5 (pl) |
| CS (1) | CS193513B2 (pl) |
| DD (1) | DD123886A5 (pl) |
| DE (1) | DE2427272C3 (pl) |
| DK (1) | DK134753C (pl) |
| EG (1) | EG11950A (pl) |
| ES (2) | ES454281A1 (pl) |
| FI (1) | FI57586C (pl) |
| FR (1) | FR2273535A1 (pl) |
| GB (1) | GB1454733A (pl) |
| HK (1) | HK26877A (pl) |
| HU (1) | HU169651B (pl) |
| IE (1) | IE41256B1 (pl) |
| IL (1) | IL47411A (pl) |
| KE (1) | KE2991A (pl) |
| LU (1) | LU72645A1 (pl) |
| NL (1) | NL181803C (pl) |
| NO (1) | NO141757C (pl) |
| PH (2) | PH12446A (pl) |
| PL (3) | PL96609B1 (pl) |
| RO (3) | RO73053A (pl) |
| SE (1) | SE414766B (pl) |
| SU (3) | SU544373A3 (pl) |
| YU (3) | YU141575A (pl) |
| ZA (1) | ZA753644B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8201321A (nl) * | 1981-04-07 | 1982-11-01 | Bayer Ag | Werkwijze voor de behandeling van metastase en de groei van tumorcellen. |
| ATE21391T1 (de) * | 1981-05-06 | 1986-08-15 | Alcusal Inc Pty Ltd | Heterocyclische kupferkomplexe. |
| US4540707A (en) * | 1983-01-28 | 1985-09-10 | Bayer Aktiengesellschaft | Nafazatrom as a lipoxygenase inhibitor |
| DK143684A (da) * | 1983-03-12 | 1984-09-13 | Bayer Ag | Anvendelse af pyrazolonderivater som lipoxygenasehaemmer ved terapi af isaer ischaemi og hjerterytmeforstyrrelser |
| USRE35801E (en) * | 1985-05-20 | 1998-05-19 | Mitsubishi Chemical Corporation | Prophylactic and therapeutic composition for circulatory disorders and method of treatment |
| DK169672B1 (da) * | 1985-05-20 | 1995-01-09 | Mitsubishi Chem Ind | Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2476986A (en) * | 1949-07-26 | Elmobe louis martin | ||
| GB599919A (en) | 1944-12-11 | 1948-03-24 | Kodak Ltd | Improvements in the manufacture of aminopyrazolones and their use as colour couplers |
| US2376380A (en) * | 1945-05-22 | Preparation of amino pyrazolones | ||
| US3147276A (en) * | 1964-09-01 | Pyrazolones | ||
| US2476987A (en) * | 1949-07-26 | S-acyloxy pyrazqles and method foe | ||
| GB636988A (en) * | 1947-12-24 | 1950-05-10 | Gevaert Photo Producten Naamlo | Improvements in and relating to the production of colour photographic images |
| US2511231A (en) * | 1949-03-26 | 1950-06-13 | Eastman Kodak Co | 1-cyanophenyl-3-acylamino-5-pyrazolone couplers for color photography |
| US2600788A (en) * | 1949-06-07 | 1952-06-17 | Eastman Kodak Co | Halogen-substituted pyrazolone couplers for color photography |
| IT482304A (pl) * | 1949-08-22 | |||
| US2672417A (en) * | 1949-12-31 | 1954-03-16 | Gevaert Photo Prod Nv | Production of color photographic images |
| GB779703A (en) | 1953-07-06 | 1957-07-24 | Hoechst Ag | Pyrazolone compounds and a process for making them |
| US2848446A (en) * | 1954-02-23 | 1958-08-19 | Saul & Co | Azo dyestuffs |
| US3014916A (en) * | 1959-01-22 | 1961-12-26 | May & Baker Ltd | Pyrazole derivatives |
| GB935538A (en) * | 1959-04-06 | 1963-08-28 | Stop Motion Devices Corp | Stop-motion head for use on knitting machines |
| GB961037A (en) | 1960-08-23 | 1964-06-17 | Smith & Nephew | Pyrazolones and processes for their preparation |
| NL121416C (pl) * | 1961-05-31 | |||
| US3190888A (en) * | 1963-08-22 | 1965-06-22 | American Home Prod | Aryloxyalkylpyrazole |
| DE1670529C3 (de) * | 1966-07-13 | 1974-01-10 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Substituierte s-Triazine |
| GB1190914A (en) | 1966-09-26 | 1970-05-06 | Agfa Gevaert Nv | 2-Pyrazolin-5-Ones and the use thereof as Colour Couplers |
| FR1558513A (pl) * | 1968-01-04 | 1969-02-28 | ||
| GB1247688A (en) | 1968-02-26 | 1971-09-29 | Agfa Gevaert | Monomeric and polymeric 2-pyrazoline-5-one colour couplers |
| JPS4818858B1 (pl) * | 1969-04-07 | 1973-06-08 | ||
| FR2068413A1 (en) | 1969-10-22 | 1971-08-27 | Synthelabo | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives |
| US3615506A (en) * | 1970-02-09 | 1971-10-26 | Eastman Kodak Co | Silver halide emulsions containing 3-cyclicamino-5-pyrazolone color couplers |
| US3694456A (en) * | 1970-05-08 | 1972-09-26 | Takeda Chemical Industries Ltd | 1-disubstituted aminopyrazoles |
| FR2101060B1 (pl) * | 1970-08-14 | 1974-02-01 | Roussel Uclaf | |
| JPS548689B1 (pl) * | 1970-12-04 | 1979-04-18 | ||
| JPS5417772B1 (pl) * | 1970-12-04 | 1979-07-03 | ||
| AR207445A1 (es) * | 1973-04-17 | 1976-10-08 | Bayer Ag | Procedimiento de preparacion de nuevos derivados de pirazolonas-(5)-1-substituidas |
| DE2319281A1 (de) * | 1973-04-17 | 1974-11-07 | Bayer Ag | Diuretisches und antihypertensives mittel |
| DE2319278C2 (de) | 1973-04-17 | 1986-02-20 | Bayer Ag, 5090 Leverkusen | Pharmazeutisches Mittel |
-
1974
- 1974-06-06 DE DE2427272A patent/DE2427272C3/de not_active Expired
-
1975
- 1975-01-01 AR AR259115A patent/AR207044A1/es active
- 1975-01-01 AR AR261807A patent/AR207177A1/es active
- 1975-01-01 AR AR261806A patent/AR207176A1/es active
- 1975-04-05 RO RO7591324A patent/RO73053A/ro unknown
- 1975-05-06 GB GB1897075A patent/GB1454733A/en not_active Expired
- 1975-05-23 NO NO751846A patent/NO141757C/no unknown
- 1975-05-24 EG EG75308A patent/EG11950A/xx active
- 1975-05-26 BG BG030936A patent/BG24410A3/xx unknown
- 1975-05-26 BG BG030937A patent/BG23005A3/xx unknown
- 1975-05-28 SU SU2138693A patent/SU544373A3/ru active
- 1975-06-02 US US05/582,773 patent/US4053621A/en not_active Expired - Lifetime
- 1975-06-02 BG BG030159A patent/BG23899A3/xx unknown
- 1975-06-02 YU YU01415/75A patent/YU141575A/xx unknown
- 1975-06-03 IL IL7547411A patent/IL47411A/xx unknown
- 1975-06-03 PH PH17223A patent/PH12446A/en unknown
- 1975-06-04 CH CH137079A patent/CH612673A5/xx not_active IP Right Cessation
- 1975-06-04 FI FI751654A patent/FI57586C/fi not_active IP Right Cessation
- 1975-06-04 AT AT424875A patent/AT342584B/de not_active IP Right Cessation
- 1975-06-04 PL PL1975193711A patent/PL96609B1/pl unknown
- 1975-06-04 DD DD186449A patent/DD123886A5/xx unknown
- 1975-06-04 DK DK253475A patent/DK134753C/da not_active IP Right Cessation
- 1975-06-04 CH CH720675A patent/CH611889A5/xx not_active IP Right Cessation
- 1975-06-04 PL PL1975180895A patent/PL93913B1/pl unknown
- 1975-06-04 JP JP50066633A patent/JPS5840544B2/ja not_active Expired
- 1975-06-04 BE BE157016A patent/BE829850A/xx not_active IP Right Cessation
- 1975-06-04 CH CH136979A patent/CH612672A5/xx not_active IP Right Cessation
- 1975-06-04 LU LU72645A patent/LU72645A1/xx unknown
- 1975-06-04 PL PL1975193710A patent/PL96608B1/pl unknown
- 1975-06-05 ZA ZA00753644A patent/ZA753644B/xx unknown
- 1975-06-05 CS CS753956A patent/CS193513B2/cs unknown
- 1975-06-05 RO RO7582444A patent/RO79056A/ro unknown
- 1975-06-05 RO RO7591325A patent/RO73054A/ro unknown
- 1975-06-05 IE IE1269/75A patent/IE41256B1/xx unknown
- 1975-06-05 SE SE7506435A patent/SE414766B/xx not_active IP Right Cessation
- 1975-06-06 FR FR7517765A patent/FR2273535A1/fr active Granted
- 1975-06-06 NL NLAANVRAGE7506765,A patent/NL181803C/xx not_active IP Right Cessation
- 1975-06-06 CA CA228,726A patent/CA1051001A/en not_active Expired
- 1975-06-06 HU HUBA3276A patent/HU169651B/hu unknown
- 1975-12-16 ES ES454281A patent/ES454281A1/es not_active Expired
-
1976
- 1976-03-12 SU SU762331907A patent/SU588917A3/ru active
- 1976-03-12 SU SU762331906A patent/SU586839A3/ru active
- 1976-10-19 PH PH19016A patent/PH14053A/en unknown
- 1976-12-16 ES ES454280A patent/ES454280A1/es not_active Expired
-
1977
- 1977-06-02 HK HK268/77A patent/HK26877A/xx unknown
-
1979
- 1979-09-11 KE KE2991A patent/KE2991A/xx unknown
-
1981
- 1981-07-08 YU YU01691/81A patent/YU169181A/xx unknown
- 1981-07-08 YU YU01692/81A patent/YU169281A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: BAYER AKTIENGESELLSCHAFT |