GB1510765A - Piperidine derivatives of indole - Google Patents

Piperidine derivatives of indole

Info

Publication number
GB1510765A
GB1510765A GB45918/76A GB4591876A GB1510765A GB 1510765 A GB1510765 A GB 1510765A GB 45918/76 A GB45918/76 A GB 45918/76A GB 4591876 A GB4591876 A GB 4591876A GB 1510765 A GB1510765 A GB 1510765A
Authority
GB
United Kingdom
Prior art keywords
compounds
indole
nov
alkyl
piperidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB45918/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1510765A publication Critical patent/GB1510765A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Abstract

1510765 Piperidinoalkylindoles BOEHRINGER MANNHEIM GmbH 4 Nov 1976 [7 Nov 1975] 45918/76 Heading C2C The invention comprises compounds of formula and their pharmacologically compatible salts, wherein R 1 , R 2 and R 3 are each H or C 1-6 alkyl, or R 3 may be halogen or C 1-6 alkoxy, and X is C 2 or C 3 alkylene. In examples, these compounds are prepared by either reacting a 3-bromoalkyl- or toxyloxyalkylindole with a 4-phenoxymethylpiperidine or introducing R 1 = alkyl. Therapeutic compositions having antihypertensive activity comprise compounds of the above formula, and may be administered orally or parenterally.
GB45918/76A 1975-11-07 1976-11-04 Piperidine derivatives of indole Expired GB1510765A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752550001 DE2550001A1 (en) 1975-11-07 1975-11-07 NEW INDOL DERIVATIVES AND PROCESS FOR THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
GB1510765A true GB1510765A (en) 1978-05-17

Family

ID=5961169

Family Applications (1)

Application Number Title Priority Date Filing Date
GB45918/76A Expired GB1510765A (en) 1975-11-07 1976-11-04 Piperidine derivatives of indole

Country Status (15)

Country Link
JP (1) JPS5259164A (en)
AT (1) AT352727B (en)
BE (1) BE847975A (en)
CA (1) CA1077941A (en)
DE (1) DE2550001A1 (en)
DK (1) DK141529C (en)
FI (1) FI763150A (en)
FR (1) FR2330396A1 (en)
GB (1) GB1510765A (en)
IE (1) IE43972B1 (en)
LU (1) LU76143A1 (en)
NL (1) NL7612288A (en)
SE (1) SE7612236L (en)
SU (1) SU628816A3 (en)
ZA (1) ZA766379B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0046179A1 (en) * 1980-07-07 1982-02-24 Hoechst-Roussel Pharmaceuticals Incorporated 3-(3-(4-(4-Fluorobenzoyl)piperidyl)propyl)-2-methyl indole and pharmaceutical composition containing it

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905876A1 (en) 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh NEW PIPERIDINOPROPYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0046179A1 (en) * 1980-07-07 1982-02-24 Hoechst-Roussel Pharmaceuticals Incorporated 3-(3-(4-(4-Fluorobenzoyl)piperidyl)propyl)-2-methyl indole and pharmaceutical composition containing it

Also Published As

Publication number Publication date
JPS5259164A (en) 1977-05-16
SU628816A3 (en) 1978-10-15
ZA766379B (en) 1977-10-26
DE2550001A1 (en) 1977-05-12
CA1077941A (en) 1980-05-20
AT352727B (en) 1979-10-10
IE43972L (en) 1977-05-07
BE847975A (en) 1977-05-04
FI763150A (en) 1977-05-08
SE7612236L (en) 1977-05-08
NL7612288A (en) 1977-05-10
DK141529C (en) 1980-09-01
DK495076A (en) 1977-05-08
FR2330396B1 (en) 1979-06-29
IE43972B1 (en) 1981-07-15
LU76143A1 (en) 1977-05-18
DK141529B (en) 1980-04-14
ATA823976A (en) 1979-03-15
FR2330396A1 (en) 1977-06-03

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee