GB1510765A - Piperidine derivatives of indole - Google Patents
Piperidine derivatives of indoleInfo
- Publication number
- GB1510765A GB1510765A GB45918/76A GB4591876A GB1510765A GB 1510765 A GB1510765 A GB 1510765A GB 45918/76 A GB45918/76 A GB 45918/76A GB 4591876 A GB4591876 A GB 4591876A GB 1510765 A GB1510765 A GB 1510765A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- indole
- nov
- alkyl
- piperidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
1510765 Piperidinoalkylindoles BOEHRINGER MANNHEIM GmbH 4 Nov 1976 [7 Nov 1975] 45918/76 Heading C2C The invention comprises compounds of formula and their pharmacologically compatible salts, wherein R 1 , R 2 and R 3 are each H or C 1-6 alkyl, or R 3 may be halogen or C 1-6 alkoxy, and X is C 2 or C 3 alkylene. In examples, these compounds are prepared by either reacting a 3-bromoalkyl- or toxyloxyalkylindole with a 4-phenoxymethylpiperidine or introducing R 1 = alkyl. Therapeutic compositions having antihypertensive activity comprise compounds of the above formula, and may be administered orally or parenterally.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752550001 DE2550001A1 (en) | 1975-11-07 | 1975-11-07 | NEW INDOL DERIVATIVES AND PROCESS FOR THEIR PRODUCTION |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1510765A true GB1510765A (en) | 1978-05-17 |
Family
ID=5961169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB45918/76A Expired GB1510765A (en) | 1975-11-07 | 1976-11-04 | Piperidine derivatives of indole |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5259164A (en) |
AT (1) | AT352727B (en) |
BE (1) | BE847975A (en) |
CA (1) | CA1077941A (en) |
DE (1) | DE2550001A1 (en) |
DK (1) | DK141529C (en) |
FI (1) | FI763150A (en) |
FR (1) | FR2330396A1 (en) |
GB (1) | GB1510765A (en) |
IE (1) | IE43972B1 (en) |
LU (1) | LU76143A1 (en) |
NL (1) | NL7612288A (en) |
SE (1) | SE7612236L (en) |
SU (1) | SU628816A3 (en) |
ZA (1) | ZA766379B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0046179A1 (en) * | 1980-07-07 | 1982-02-24 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(3-(4-(4-Fluorobenzoyl)piperidyl)propyl)-2-methyl indole and pharmaceutical composition containing it |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2905876A1 (en) | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | NEW PIPERIDINOPROPYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
-
1975
- 1975-11-07 DE DE19752550001 patent/DE2550001A1/en not_active Withdrawn
-
1976
- 1976-10-25 ZA ZA766379A patent/ZA766379B/en unknown
- 1976-10-28 CA CA264,610A patent/CA1077941A/en not_active Expired
- 1976-10-29 IE IE2396/76A patent/IE43972B1/en unknown
- 1976-11-02 SU SU762415646A patent/SU628816A3/en active
- 1976-11-02 DK DK495076A patent/DK141529C/en active
- 1976-11-03 FI FI763150A patent/FI763150A/fi not_active Application Discontinuation
- 1976-11-03 SE SE7612236A patent/SE7612236L/en not_active Application Discontinuation
- 1976-11-04 GB GB45918/76A patent/GB1510765A/en not_active Expired
- 1976-11-04 BE BE172070A patent/BE847975A/en unknown
- 1976-11-05 LU LU76143A patent/LU76143A1/xx unknown
- 1976-11-05 JP JP51133141A patent/JPS5259164A/en active Pending
- 1976-11-05 AT AT823976A patent/AT352727B/en not_active IP Right Cessation
- 1976-11-05 FR FR7633391A patent/FR2330396A1/en active Granted
- 1976-11-05 NL NL7612288A patent/NL7612288A/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0046179A1 (en) * | 1980-07-07 | 1982-02-24 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(3-(4-(4-Fluorobenzoyl)piperidyl)propyl)-2-methyl indole and pharmaceutical composition containing it |
Also Published As
Publication number | Publication date |
---|---|
JPS5259164A (en) | 1977-05-16 |
SU628816A3 (en) | 1978-10-15 |
ZA766379B (en) | 1977-10-26 |
DE2550001A1 (en) | 1977-05-12 |
CA1077941A (en) | 1980-05-20 |
AT352727B (en) | 1979-10-10 |
IE43972L (en) | 1977-05-07 |
BE847975A (en) | 1977-05-04 |
FI763150A (en) | 1977-05-08 |
SE7612236L (en) | 1977-05-08 |
NL7612288A (en) | 1977-05-10 |
DK141529C (en) | 1980-09-01 |
DK495076A (en) | 1977-05-08 |
FR2330396B1 (en) | 1979-06-29 |
IE43972B1 (en) | 1981-07-15 |
LU76143A1 (en) | 1977-05-18 |
DK141529B (en) | 1980-04-14 |
ATA823976A (en) | 1979-03-15 |
FR2330396A1 (en) | 1977-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |