GB1500962A - Furo(2,3-d)pyrimidine derivatives - Google Patents
Furo(2,3-d)pyrimidine derivativesInfo
- Publication number
- GB1500962A GB1500962A GB1066875A GB1066875A GB1500962A GB 1500962 A GB1500962 A GB 1500962A GB 1066875 A GB1066875 A GB 1066875A GB 1066875 A GB1066875 A GB 1066875A GB 1500962 A GB1500962 A GB 1500962A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- furo
- compounds
- march
- pyrimidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1500962 Furo[2,3-d]pyrimidines EISAI CO Ltd 14 March 1975 [14 March 1974] 10668/75 Heading C2C The invention comprises compounds of formula and their pharmacologically acceptable acid addition salts, wherein R<SP>1</SP> is alkyl, alkenyl or aralkyl and R<SP>2</SP> is alkyl or Ph (optionally substituted by CO 2 H, CO 2 R, RSO 2 or NO 2 , where R is alkyl). These compounds are prepared by reacting a 2-R<SP>1</SP>S-4-HO-6-NH 2 -substituted pyrimidine with R<SP>2</SP>COCH 2 X, where X is halogen. Therapeutic compositions having anti-inflammatory and analgesic activity comprise compounds of the above formula, which are stated to be especially suitable for oral administration.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2862874A JPS523957B2 (en) | 1974-03-14 | 1974-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1500962A true GB1500962A (en) | 1978-02-15 |
Family
ID=12253808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1066875A Expired GB1500962A (en) | 1974-03-14 | 1975-03-14 | Furo(2,3-d)pyrimidine derivatives |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS523957B2 (en) |
DE (1) | DE2511316A1 (en) |
FR (1) | FR2263776B1 (en) |
GB (1) | GB1500962A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4180577A (en) | 1974-03-14 | 1979-12-25 | Eisai Co., Ltd. | Furo[2, 3d]pyrimidine derivatives and anti-ulcer containing the same |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4153695A (en) * | 1978-03-09 | 1979-05-08 | Eli Lilly And Company | Substituted 2,3-dihydro imidazo[1,2-c]pyrimidines |
US4408047A (en) * | 1980-03-28 | 1983-10-04 | Merck & Co., Inc. | Imidazodiazines |
US4503050A (en) * | 1983-06-02 | 1985-03-05 | Riker Laboratories, Inc. | Substituted imidazo[1,2-c]pyrimidines |
GB8334210D0 (en) * | 1983-12-22 | 1984-02-01 | Roussel Lab Ltd | Imidazo(1 2-c)pyrimidines |
MC1673A1 (en) * | 1984-06-27 | 1986-06-03 | Wellcome Found | ARYLIC DERIVATIVES OF IMIDAZOLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF DRUGS |
DE3446778A1 (en) * | 1984-12-21 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | NEW IMIDAZO DERIVATIVES, THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
-
1974
- 1974-03-14 JP JP2862874A patent/JPS523957B2/ja not_active Expired
-
1975
- 1975-03-14 FR FR7507987A patent/FR2263776B1/fr not_active Expired
- 1975-03-14 GB GB1066875A patent/GB1500962A/en not_active Expired
- 1975-03-14 DE DE19752511316 patent/DE2511316A1/en not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4180577A (en) | 1974-03-14 | 1979-12-25 | Eisai Co., Ltd. | Furo[2, 3d]pyrimidine derivatives and anti-ulcer containing the same |
Also Published As
Publication number | Publication date |
---|---|
FR2263776A1 (en) | 1975-10-10 |
JPS523957B2 (en) | 1977-01-31 |
JPS50131991A (en) | 1975-10-18 |
DE2511316A1 (en) | 1975-09-18 |
FR2263776B1 (en) | 1978-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |