FR2273535A1 - 1-(2-(beta-naphtyloxy)-ethyl)-3-methyl-pyrazolone-(5), procedes pour son obtention et application comme agent anti-thrombose - Google Patents

1-(2-(beta-naphtyloxy)-ethyl)-3-methyl-pyrazolone-(5), procedes pour son obtention et application comme agent anti-thrombose

Info

Publication number
FR2273535A1
FR2273535A1 FR7517765A FR7517765A FR2273535A1 FR 2273535 A1 FR2273535 A1 FR 2273535A1 FR 7517765 A FR7517765 A FR 7517765A FR 7517765 A FR7517765 A FR 7517765A FR 2273535 A1 FR2273535 A1 FR 2273535A1
Authority
FR
France
Prior art keywords
beta
naphtyloxy
pyrazolone
ethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7517765A
Other languages
English (en)
Other versions
FR2273535B1 (fr
Inventor
E Moller
I H F Meng
F Seuter
E Wehinger
H Horstmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of FR2273535A1 publication Critical patent/FR2273535A1/fr
Application granted granted Critical
Publication of FR2273535B1 publication Critical patent/FR2273535B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7517765A 1974-06-06 1975-06-06 1-(2-(beta-naphtyloxy)-ethyl)-3-methyl-pyrazolone-(5), procedes pour son obtention et application comme agent anti-thrombose Granted FR2273535A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2427272A DE2427272C3 (de) 1974-06-06 1974-06-06 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum

Publications (2)

Publication Number Publication Date
FR2273535A1 true FR2273535A1 (fr) 1976-01-02
FR2273535B1 FR2273535B1 (fr) 1978-12-01

Family

ID=5917444

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7517765A Granted FR2273535A1 (fr) 1974-06-06 1975-06-06 1-(2-(beta-naphtyloxy)-ethyl)-3-methyl-pyrazolone-(5), procedes pour son obtention et application comme agent anti-thrombose

Country Status (32)

Country Link
US (1) US4053621A (fr)
JP (1) JPS5840544B2 (fr)
AR (3) AR207176A1 (fr)
AT (1) AT342584B (fr)
BE (1) BE829850A (fr)
BG (3) BG23005A3 (fr)
CA (1) CA1051001A (fr)
CH (3) CH612673A5 (fr)
CS (1) CS193513B2 (fr)
DD (1) DD123886A5 (fr)
DE (1) DE2427272C3 (fr)
DK (1) DK134753C (fr)
EG (1) EG11950A (fr)
ES (2) ES454281A1 (fr)
FI (1) FI57586C (fr)
FR (1) FR2273535A1 (fr)
GB (1) GB1454733A (fr)
HK (1) HK26877A (fr)
HU (1) HU169651B (fr)
IE (1) IE41256B1 (fr)
IL (1) IL47411A (fr)
KE (1) KE2991A (fr)
LU (1) LU72645A1 (fr)
NL (1) NL181803C (fr)
NO (1) NO141757C (fr)
PH (2) PH12446A (fr)
PL (3) PL96609B1 (fr)
RO (3) RO73053A (fr)
SE (1) SE414766B (fr)
SU (3) SU544373A3 (fr)
YU (3) YU141575A (fr)
ZA (1) ZA753644B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502954A1 (fr) * 1981-04-07 1982-10-08 Bayer Ag Medicament a base de 3-methyl-1-(2-(2-naphtyloxy)-ethyl)-2-pyrazoline-5-one pour la reduction de la metastase

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0064862B1 (fr) * 1981-05-06 1986-08-13 Alcusal Incorporated Pty. Ltd. Complexes hétérocycliques de cuivre
US4540707A (en) * 1983-01-28 1985-09-10 Bayer Aktiengesellschaft Nafazatrom as a lipoxygenase inhibitor
DK143684A (da) * 1983-03-12 1984-09-13 Bayer Ag Anvendelse af pyrazolonderivater som lipoxygenasehaemmer ved terapi af isaer ischaemi og hjerterytmeforstyrrelser
DK169672B1 (da) * 1985-05-20 1995-01-09 Mitsubishi Chem Ind Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater
USRE35801E (en) * 1985-05-20 1998-05-19 Mitsubishi Chemical Corporation Prophylactic and therapeutic composition for circulatory disorders and method of treatment

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2376380A (en) * 1945-05-22 Preparation of amino pyrazolones
US2476986A (en) * 1949-07-26 Elmobe louis martin
GB599919A (en) 1944-12-11 1948-03-24 Kodak Ltd Improvements in the manufacture of aminopyrazolones and their use as colour couplers
US3147276A (en) * 1964-09-01 Pyrazolones
US2476987A (en) * 1949-07-26 S-acyloxy pyrazqles and method foe
GB636988A (en) * 1947-12-24 1950-05-10 Gevaert Photo Producten Naamlo Improvements in and relating to the production of colour photographic images
US2511231A (en) * 1949-03-26 1950-06-13 Eastman Kodak Co 1-cyanophenyl-3-acylamino-5-pyrazolone couplers for color photography
US2600788A (en) * 1949-06-07 1952-06-17 Eastman Kodak Co Halogen-substituted pyrazolone couplers for color photography
LU30278A1 (fr) * 1949-08-22
US2672417A (en) * 1949-12-31 1954-03-16 Gevaert Photo Prod Nv Production of color photographic images
GB779703A (en) 1953-07-06 1957-07-24 Hoechst Ag Pyrazolone compounds and a process for making them
US2848446A (en) * 1954-02-23 1958-08-19 Saul & Co Azo dyestuffs
US3014916A (en) * 1959-01-22 1961-12-26 May & Baker Ltd Pyrazole derivatives
GB935538A (en) * 1959-04-06 1963-08-28 Stop Motion Devices Corp Stop-motion head for use on knitting machines
GB961037A (en) 1960-08-23 1964-06-17 Smith & Nephew Pyrazolones and processes for their preparation
NL279140A (fr) * 1961-05-31
US3190888A (en) * 1963-08-22 1965-06-22 American Home Prod Aryloxyalkylpyrazole
DE1670529C3 (de) * 1966-07-13 1974-01-10 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Substituierte s-Triazine
GB1190914A (en) 1966-09-26 1970-05-06 Agfa Gevaert Nv 2-Pyrazolin-5-Ones and the use thereof as Colour Couplers
FR1558513A (fr) * 1968-01-04 1969-02-28
GB1247688A (en) 1968-02-26 1971-09-29 Agfa Gevaert Monomeric and polymeric 2-pyrazoline-5-one colour couplers
JPS4818858B1 (fr) * 1969-04-07 1973-06-08
FR2068413A1 (en) 1969-10-22 1971-08-27 Synthelabo 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives
US3615506A (en) * 1970-02-09 1971-10-26 Eastman Kodak Co Silver halide emulsions containing 3-cyclicamino-5-pyrazolone color couplers
US3694456A (en) * 1970-05-08 1972-09-26 Takeda Chemical Industries Ltd 1-disubstituted aminopyrazoles
FR2101060B1 (fr) * 1970-08-14 1974-02-01 Roussel Uclaf
JPS548689B1 (fr) * 1970-12-04 1979-04-18
JPS5417772B1 (fr) * 1970-12-04 1979-07-03
AR207445A1 (es) * 1973-04-17 1976-10-08 Bayer Ag Procedimiento de preparacion de nuevos derivados de pirazolonas-(5)-1-substituidas
DE2319281A1 (de) * 1973-04-17 1974-11-07 Bayer Ag Diuretisches und antihypertensives mittel
DE2319278C2 (de) 1973-04-17 1986-02-20 Bayer Ag, 5090 Leverkusen Pharmazeutisches Mittel

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502954A1 (fr) * 1981-04-07 1982-10-08 Bayer Ag Medicament a base de 3-methyl-1-(2-(2-naphtyloxy)-ethyl)-2-pyrazoline-5-one pour la reduction de la metastase
EP0062319A1 (fr) * 1981-04-07 1982-10-13 Bayer Ag 3-Methyl-1-(2-(3-naphthyloxy)-ethyl)-2-pyrazolin-5-one pour le traitement de la métastase et la croissance des cellules tumorales

Also Published As

Publication number Publication date
YU169181A (en) 1982-02-28
AR207177A1 (es) 1976-09-15
SE414766B (sv) 1980-08-18
BE829850A (fr) 1975-12-04
AR207044A1 (es) 1976-09-09
IL47411A0 (en) 1975-08-31
YU169281A (en) 1982-02-28
AT342584B (de) 1978-04-10
AU8179775A (en) 1976-12-09
ATA424875A (de) 1977-08-15
SU586839A3 (ru) 1977-12-30
CA1051001A (fr) 1979-03-20
KE2991A (en) 1979-09-28
FI751654A (fr) 1975-12-07
CH612673A5 (fr) 1979-08-15
BG24410A3 (en) 1978-02-10
EG11950A (en) 1978-12-31
FR2273535B1 (fr) 1978-12-01
DE2427272B2 (de) 1980-07-24
RO79056A (fr) 1982-06-25
RO73054A (fr) 1981-11-24
BG23899A3 (en) 1977-11-10
DK253475A (da) 1975-12-07
RO73053A (fr) 1981-09-24
NO751846L (fr) 1975-12-09
JPS5840544B2 (ja) 1983-09-06
US4053621A (en) 1977-10-11
HU169651B (fr) 1977-02-28
FI57586C (fi) 1980-09-10
DK134753C (da) 1977-06-06
DE2427272A1 (de) 1976-01-08
SU588917A3 (ru) 1978-01-15
AR207176A1 (es) 1976-09-15
NO141757C (no) 1980-05-07
NL181803C (nl) 1987-11-02
DD123886A5 (fr) 1977-01-19
ES454281A1 (es) 1977-11-16
DE2427272C3 (de) 1981-10-01
PH14053A (en) 1980-12-29
CS193513B2 (en) 1979-10-31
DK134753B (da) 1977-01-10
NO141757B (no) 1980-01-28
GB1454733A (en) 1976-11-03
LU72645A1 (fr) 1976-03-17
ZA753644B (en) 1976-04-28
NL7506765A (nl) 1975-12-09
IE41256B1 (en) 1979-11-21
SE7506435L (sv) 1975-12-08
CH612672A5 (fr) 1979-08-15
JPS5113766A (en) 1976-02-03
PH12446A (en) 1979-03-08
IE41256L (en) 1975-12-06
YU141575A (en) 1982-02-28
PL93913B1 (fr) 1977-07-30
ES454280A1 (es) 1977-12-01
FI57586B (fi) 1980-05-30
IL47411A (en) 1979-07-25
BG23005A3 (fr) 1977-05-20
HK26877A (en) 1977-06-10
PL96608B1 (pl) 1978-01-31
PL96609B1 (pl) 1978-01-31
NL181803B (nl) 1987-06-01
SU544373A3 (ru) 1977-01-25
CH611889A5 (fr) 1979-06-29

Similar Documents

Publication Publication Date Title
FR2273535A1 (fr) 1-(2-(beta-naphtyloxy)-ethyl)-3-methyl-pyrazolone-(5), procedes pour son obtention et application comme agent anti-thrombose
ES477784A1 (es) Procedimiento para la preparacion de nuevas 2-fenilimino-imidazolidinas sustituidas.
EP0106541A3 (fr) Pré-médicaments de pilocarpine
ES465537A1 (es) Un procedimiento para la preparacion de un alcohol-x-(3,4- dimetoxifenetilaminometil)-2-alcoxibencilico racemico u op- ticamente activo
GB1497729A (en) Benzenesulphonyl ureas and process for their manufacture
JPS5287173A (en) 4-(pyridyl-2-oxy)phynoxyalkanecarboxylic acid compounds
GB1468644A (en) Tetrahydropyridine carboxylic acid esters and salts thereof and their use as insecticidal and acaricidal agents
GB1489850A (en) N-propargyl-anilinomethylenemalodinitrile derivatives
JPS5770872A (en) Imidazole derivative and biosynthetic inhibitor against thromboxana a2 containg the same
GB1480429A (en) Ethers and thioethers and their use as pesticides
KR830009000A (ko) 2-벤조일아미노-치환벤질아민 유도체 및 그 제조방법
ES390039A1 (es) Un procedimiento para la preparacion de agentes antibacte- rianos.
JPS53111078A (en) Carbostyril derivative
GB1292662A (en) Bicycloheptaneheptanoic acids and esters thereof
JPS5350182A (en) Carbostyril derivatives
GB1439108A (en) Thiono-thiolphosphoric acid esters and their use as insecticides and acaricides
GB1500359A (en) 4-aminopyrimidine derivatives
JPS5683419A (en) Remedy for hypertension
SE8106254L (sv) Forfarande for framstellning av alkyletrar
ES380034A1 (es) Un procedimiento para la preparacion de dietinilcarbinoles sustituidos.
JPS52130820A (en) Production of tetrachloronaphthalic acid derivative
GB1510795A (en) 2-(2'-chloro-3'-substituted-4-oxo)azetidinyl-3-methyl-3-butenoates
JPS53108989A (en) Carbostyril derivative
GB1279561A (en) Thiazolylacetic acid derivatives, methods of making them, and compositions containing them

Legal Events

Date Code Title Description
ST Notification of lapse